- Tytuł:
- Isozymes delta of phosphoinositide-specific phospholipase C and their role in signal transduction in the cell.
- Autorzy:
-
Ochocka, Anna-Maria
Pawelczyk, Tadeusz - Tematy:
-
structure
δ isozymes
second messengers
PIP2
regulation
phospholipase C - Pokaż więcej
- Wydawca:
- Polskie Towarzystwo Biochemiczne
- Powiązania:
- https://bibliotekanauki.pl/articles/1043391.pdf Link otwiera się w nowym oknie
- Opis:
- Phospholipase C (PLC, EC 3.1.4.11) is an enzyme crucial for the phosphoinositol pathway and whose activity is involved in eukaryotic signal transduction as it generates two second messengers: diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). There are four major types of phospholipase C named: β, γ, δ and the recently discovered ε, but this review will focus only on the recent advances for the γ isozymes of PLC. So far, four d isozymes (named γ1-4) have been discovered and examined. They differ with regard to cellular distribution, activities, biochemical features and involvement in human ailments.
- Dostawca treści:
- Biblioteka Nauki
Artykuł