- Tytuł:
- Is PM1 similar to PM2.5? : a new insight into the association of PM1 and PM2.5 with childrens lung function
- Autorzy:
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Xiao-Wen, Zeng
Li-Wen, Hu
Knibbs, Luke D
Bloom, Michael S.
Guang-Hui, Dong
Guo, Yu-Ming
Mika, Komppula
Dharmage, Shyamali C.
Qi-Hua, Guan
Jalaludin, Bin
Heinrich, Joachim
Hong-Yao, Yu
Pasi, Jalava
Shao, Lin
Bo-Yi, Yang
Mo, Yang
Maija-Riitta, Hirvonen
Zi-Mian, Liang
Lan, Steve Hung
Marjut, Roponen
Markevych, Iana
Morawska, Lidia - Opis:
- Experimental data suggests that PM1 is more toxic than PM2.5 although the epidemiologic evidence suggests that the health associations are similar. However, few objective exposure data are available to compare the associations of PM1 and PM2.5 with children lung function. Our objectives are a) to evaluate associations between long-term exposure to PM1, PM2.5 and children’s lung function, and b) to compare the associations between PM1 and PM2.5. From 2012 to 2013, we enrolled 6,740 children (7-14 years), randomly recruited from primary and middle schools located in seven cities in northeast China. We measured lung function including forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1), peak expiratory flow (PEF), and maximal mid-expiratory flow (MMEF) utilizing two portable electronic spirometers. We dichotomized continuous lung function measures according the expected values for gender and age. The spatial resolution at which PM1 and PM2.5 estimated were estimated using a machine learning method and the temporal average concentrations were averaged from 2009 to 2012. A multilevel regression model was used to estimate the associations of PM1, PM2.5 exposure and lung function measures, adjusted for confounding factors. Associations with lower lung function were consistently larger for PM1 than for PM2.5. Adjusted odds ratios (OR) per interquartile range greater PM1 ranged from 1.53 for MMEF (95% confidence interval [CI]: 1.20-1.96) to 2.14 for FEV1 (95% CI: 1.66-2.76) and ORs for PM2.5 ranged from 1.36 for MMEF (95%CI: 1.12–1.66) to 1.82 for FEV1 (95%CI: 1.49-2.22), respectively. PM1 and PM2.5 had.
- Dostawca treści:
- Repozytorium Uniwersytetu Jagiellońskiego
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