Temat: interaction - Prolib Integro

Skocz do pozycji: 1.

Tytuł:: Fluorescence correlation spectroscopy for multiple-site equilibrium binding: a case of doxorubicin–DNA interaction
Autorzy:: Poniewierski, Andrzej
Sozański, Krzysztof
Zhou, Ying
Brzozowska-Elliott, Anna
Hołyst, Robert
Zhang, Xuzhu
Wydawca:: Royal Society of Chemistry
Cytata wydawnicza:: Phys.Chem.Chem.Phys., 2019, 21, 1572-1577
Opis:: Quantitative description of the interaction between doxorubicin (DOX), a broadly used anticancer drug,and DNA is the key to understand the action mechanism and side effects of its clinical use. However,the reported equilibrium constants of DOX–DNA interaction obtained using a range of different analytical methods vary even by several orders of magnitude. Herein, we propose a novel application of a single-molecule technique – fluorescence correlation spectroscopy (FCS) – to probe the interaction between DOX and two types of DNA (pUC19 and calf thymus DNA), taking advantage of intrinsic self-fluorescence of DOX. We provide an analytical formula for autocorrelation analysis to determine the equilibriumconstant of DOX–DNA complex-formation, where binding of multiple DOX molecules to a DNA chain is included in the reaction–diffusion model. Our FCS-based method not only quantitatively revealed the values of equilibrium constant, but also implied that the stability of DOX–DNA complex is related to the types of base pair rather than the length or structure of the DNA. This work opens a promising pathway toward quantitative determination of molecular interactions in complex systems such as living cells or organisms at single-molecule level.
Dostawca treści:: Repozytorium Centrum Otwartej Nauki

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Skocz do pozycji: 2.

Tytuł:: Characterization of charge transfer excited states in [2Fe–2S] iron–sulfur clusters using conventional configuration interaction techniques
Autorzy:: Kubas, Adam
Wydawca:: Springer
Cytata wydawnicza:: Kubas, A. Characterization of charge transfer excited states in [2Fe–2S] iron–sulfur clusters using conventional configuration interaction techniques. Theor Chem Acc 139, 120 (2020). https://doi.org/10.1007/s00214-020-02635-7
Opis:: The experimental UV–Vis spectra of the biologically relevant [2Fe–2S] iron–sulfur clusters feature typically three bands in the 300–800 nm range. Based on ground-state orbitals and using the one electron transition picture, these bands are said to be of charge transfer character. The key complication in the electronic structure calculations of these compounds are the antiferromagnetic coupling of the iron centers and high covalency of Fe–S bonds. Thus, the examples of the direct computations of electronically excited states of these systems are rare. Whereas low lying electronic excited states were subject of recent studies, higher energy states computed with many-body theories were never reported. In this work we present, for the first time, calculations of the electronic spectra of [Fe2S2](SMe) 2− 4 biomimetic compound. We demonstrate that spin-averaged restricted open-shell Hartree–Fock orbitals are superior to high-spin orbitals and are convenient reference for subsequent configuration interaction calculations. Moreover, the use of conventional configuration interaction methods enabled us to study the nature of the excited states in details with the difference density maps. By systematic extension of the donor orbital space we show that key excitations in the 300–800 nm range are of Fe 3d ← (μ-S) character.
National Science Centre, Poland (NCN)
Dostawca treści:: Repozytorium Centrum Otwartej Nauki

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Skocz do pozycji: 3.

Tytuł:: Rènao: What does it mean to have a good time the Chinese way? An ethnopragmatic exploration of a Chinese cultural keyword
Autorzy:: Kornacki, Paweł
Wydawca:: Instytut Lingwistyki Stosowanej UW
Opis:: "East-Asian and Central-European Encounters in Discourse Analysis and Translation", Edited by: Anna Duszak, Arkadiusz Jabłoński and Agnieszka Leńko-Szymańska, pp. 57-82.
The paper examines the main uses and the symbolic significance of the Chinese cultural keyword rènao. Often rendered in English with its literal gloss of ‘hot and noisy’, it has been viewed by both Chinese and Western scholars as primary in making sense of Chinese social behaviour, across a variety of contexts. The present study analyses two Chinese cultural texts – a report from a local temple festival and a debate over two different styles of feasting, which frequently rely on this salient cultural notion. While the formula crowds, events, noise in the psychological literature dealing with this Chinese social value is often confirmed by the described cultural data, it is argued that close attention to the meaning and form of the descriptive language used by the cultural actors yields valuable insights into indigenous viewpoints. In particular, the notion of rènao turns out to be closely intertwined with other prominent Chinese cultural concerns, such as the idea of rénqíngwèi (‘flavour of human feelings’), Chinese cultural identity, Chinese language, and a particularly complex culinary culture as described in the anthropological literature.
Dostawca treści:: Repozytorium Centrum Otwartej Nauki

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Skocz do pozycji: 4.

Tytuł:: Competence Development Within the Polish Police Organisation
Autorzy:: Letkiewicz, Arkadiusz
Wydawca:: Akademia Policji w Szczytnie
Cytata wydawnicza:: Letkiewicz A., Competence Development Within the Polish Police Organisation, "Internal Security" 2024, nr 2(16), s. 7-17.
Opis:: In this article, the author presents the results of scientific research related to the conducted diagnosis of the social system of the Polish Police with regard to the need to develop the competence of its employees. A diagnostic method based on Rensis Likert's concept of ‘organisational health’ was used to conduct the research. The starting point of this method is a detailed analysis of the organisation in terms of: decision-making processes, the nature of supervisor-subordinate interaction, communication processes within the organisation, ways of motivating people to work, ways and nature of organisational control, and ways of establishing organisational goals.
In diesem Artikel stellt der Autor die Ergebnisse wissenschaftlicher Untersuchungen dar, die im Zusammenhang mit der Diagnose des Sozialsystems der polnischen Polizei im Hinblick auf die Notwendigkeit der Entwicklung der Kompetenzen ihrer Mitarbeiter durchgeführt wurden. Zur Durchführung der Untersuchung wurde eine Diagnosemethode verwendet, die auf dem Konzept der "organisatorischen Gesundheit" von Rensis Likert basiert. Der Ausgangspunkt dieser Methode ist eine detaillierte Analyse der Organisation im Hinblick auf die Entscheidungsprozesse, die Art der Interaktion zwischen Vorgesetzten und Untergebenen, die Kommunikationsprozesse innerhalb der Organisation, die Wege der Arbeitsmotivation, die Wege und Art der Organisationskontrolle und die Wege der Formulierung von Organisationszielen.
В данной статье автор представляет результаты научного исследования, проведенного в связи с изучением социальной системы польской полиции с точки зрения необходимости развития компетенций ее сотрудников. Для проведения исследования был использован диагностический метод, основанный на концепции «организационного здоровья» Ренсиса Лайкерта. Базовым моментом данного метода является тщательный анализ организации с точки зрения: процессов принятия решений, характера взаимодействия между начальником и подчиненным, процессов общения внутри организации, способов мотивации сотрудников, способов и характера организационного контроля и способов формулирования организационных целей.
W artykule autor prezentuje wyniki badań naukowych związanych z przeprowadzoną diagnozą systemu społecznego polskiej Policji pod kątem potrzeby rozwoju kompetencji jej pracowników. Do przeprowadzenia badań wykorzystano metodę diagnostyczną opartą na koncepcji "zdrowia organizacyjnego" Rensisa Likerta. Punktem wyjścia tej metody jest szczegółowa analiza organizacji pod kątem: procesów decyzyjnych, charakteru interakcji przełożony-podwładny, procesów komunikacji wewnątrz organizacji, sposobów motywowania ludzi do pracy, sposobów i charakteru kontroli organizacyjnej oraz sposobów formułowania celów organizacyjnych.
Dostawca treści:: Repozytorium Centrum Otwartej Nauki

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Skocz do pozycji: 5.

Tytuł:: Application of GGE biplot graphs in multi-environment trials on selection of forest trees
Autorzy:: Ukalski, Krzysztof
Klisz, Marcin
Wydawca:: The Forest Sciences and Committee on Forestry Sciences and Wood Technology of the Polish Academy of Sciences; Instytut Badawczy Lesnictwa (Forest Research Institute), Sekocin Stary, Poland
Opis:: In the studies on selection and population genetics of forest trees that include the analysis of genotype × environment interaction (GE), the use of biplot graphs is relatively rare. This article describes the models and analytic methods useful in the biplot graphs, which enable the analyses of mega-environments, selection of the testing environment, as well as the evaluation of genotype stability. The main method presented in the paper is the GGE biplot method (G – genotype effect, GE –genotype × environment interaction effect). At the same time, other methods have also been referred to, such as, SVD (singular value decomposition), PCA (principal component analysis), linear-bilinear SREG model (sites regression), linear-bilinear GREG model (genotypes regression) and AMMI (additive main effects multiplicative interaction). The potential of biplot method is presented based on the data on growth height of 20 European beech genotypes (Fagus sylvatica L.), generated from real data concerning selection trials and carried out in 5 different environments. The combined ANOVA was performed using fixed-effects, as well as mixed-effects models, and significant interaction GE was shown. The GGE biplot graphs were constructed using PCA. The first principal component (GGE1) explained 54%, and the second (GGE2) explained more than 23% of the total variation. The similarity between environments was evaluated by means of the AEC method, which allowed us to determine one mega-environment that comprised of 4 environments. None of the tested environments represented the ideal one for trial on genotype selection. The GGE biplot graphs enabled: (a) the detection of a stable genotype in terms of tree height (high and low), (b) the genotype evaluation by ranking with respect to the height and genotype stability, (c) determination of an ideal genotype, (d) the comparison of genotypes in 2 chosen environments.
Przemysław Szmit
Dostawca treści:: Repozytorium Centrum Otwartej Nauki

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Skocz do pozycji: 6.

Tytuł:: The Problem of Symbolic Interaction and of Constructing Self
Problem symbolicznej interakcji a konstruowanie jaźni
Autorzy:: Konecki, Krzysztof Tomasz
Wydawca:: Lodz University, Faculty of Economics and Sociology, Institute of Sociology
Cytata wydawnicza:: Konecki, Krzysztof T. (2005) “The Problem of Symbolic Interaction and of Constructing Self.” Qualitative Sociology Review, Vol. I Issue 1. Retrieved Month, Year (http://www.qualitativesociologyreview.org /ENG/archive_eng.php)
Opis:: Krzysztof Konecki
In the article we make an analysis of a thesis that verbal symbolic interaction is a necessary condition of constructing self. The main concepts used in the paper are: symbolic interaction, self and corporality. The aforementioned thesis and the concept of symbolic interaction originate from G.H Mead, who set the trend of thinking about interaction in human society in sociology and social psychology. This influence is noticeable up to this day. Symbolic interaction as a tool of understanding others actions and informing partners about our intensions is clearly visible in “languagecentred” and anthropocentrically oriented analyses of interactions as well as in the concentration on linguistic conditions of creating a self. Self is understood as an interpreted concept of a person but mainly in a process of social perception of a human by others occurring in interactions based on verbal language. In the article we want to develop a thesis about “nonlinguistic” possibilities of constructing interactions and self. The aforementioned thesis has been many times elaborated so far together with critical analyses of G. H. Mead (Irvin, 2004, Sanders, 1993, 1999, 2003; Myers, 1999, 2003). We want to integrate these elaborations, including our empirical experiences from a research on “The Social World of Pet’s Owners’ (research done in 2001-2005) on theoretical level and concentrate more on corporality and emotions issues and their relations to symbolic interaction and self. G.H. Mead’s views on this topic are analysed with regard to their methodological consistency and adequacy. In the article there is another thesis proposed, that interactions between animals also have meanings and, sometimes, symbolic nature, or sometimes, non symbolic one, and not necessarily related to use of a verbal language. The creation of self is connected with issues of corporality that includes: 1. nonverbal communication, 2. a relation of bodies in physical space, 3. the so called “kinesthetic empathy”, 4. emotions connected with body, mind and self processes. These elements of corporality may be the basis for taking the role of other. Researches and analyses of many sociologists (beginning from Ch. H. Cooley) show that self is often pre-verbal and that exclusion of an individual from her/his surroundings takes place also with the aid of the body and emotions tightly connected with functioning of self. The analysis of interactions between humans and animals provides us with much methodological and theoretical inspiration. Those researches and analyses obviously face a problem of “anthropomorphization of human behaviour”, which is of frequent occurrence both among researchers and ordinary people. New sociological sub-discipline called the sociology of human - non-human animals relationships adds a lot of new threads to the abovementioned deliberations on conditions of constructing self.
Dostawca treści:: Repozytorium Centrum Otwartej Nauki

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Skocz do pozycji: 7.

Tytuł:: User Experience Research and development of knowledge in the field of Human-Computer Interaction
Autorzy:: Niedziółka, Tomasz
Wydawca:: Wydawnictwo Naukowe Uniwersytetu Szczecińskiego
Cytata wydawnicza:: Niedziółka, T. (2018). User Experience Research and development of knowledge in the field of Human-Computer Interaction. Studia i Prace WNEIZ US, 54/2, pp. 71–81.
Opis:: The aim of the article is to present the impact of User Experience Research on the development of knowledge in the area of Human-Computer Interaction (HCI). The article uses the Narrative Literature Review Method. The article uses literature and scientific articles on the subjects analyzed in its issues. Based on the analysis, it was found that User Experience Research influences the development of knowledge in the area of Human-Computer Interaction by: providing results of the research related to the issues that are of a significant interest to the HCI; the applicative character of the UX research results, allowing to improve the interaction between a human and a computer; providing new research methods to the HCI discipline.
Dostawca treści:: Repozytorium Centrum Otwartej Nauki

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Skocz do pozycji: 8.

Tytuł:: Teacher-student Collaboration: Challenges and Opportunities
Autorzy:: Smyrnova-Trybulska, Eugenia
Makhachashvili, Rusudan
Pavlova, Hanna
Morze, Nataliia
Wydawca:: Studio NOA for University of Silesia in Katowice
Cytata wydawnicza:: Nataliia Morze, Hanna Pavlova, Rusudan Makhahchashvili, Eugenia Smyrnova-Trybulska, TEACHER-STUDENT COLLABORATION: CHALLENGES AND OPPORTUNITIES, [in] DISTANCE EDUCATION RESEARCH FIELDS AND METHODS, ed. Eugenia Smyrnova-Trybulska, Studio-Noa for University of Silesia, Katowice-Cieszyn 2016, 479 p., ISBN 978-83-60071-86-1, p. 195-208.
Opis:: Collaborative learning is meant to benefit agents of education due to the fact that it could sharpen skills in collaboration (remote collaboration) as a process of cooperation to accomplish objectives by combining mutual efforts in the dialogue and interaction to eventually get results for all the participants of the process. The paper analyzes the essence of collaborative learning, theoretical perspectives on collaboration in educational process and CL benefits. The study examines collaborative learning classroom. The discussion focuses on challenges and opportunities in collaborative learning.
Dostawca treści:: Repozytorium Centrum Otwartej Nauki

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Skocz do pozycji: 9.

Tytuł:: The Positives of Cross-cultural Interactions in Multinational Companies
Autorzy:: Chmielecki, Michał
Przytuła, Sylwia
Rozkwitalska, Malgorzata
Cytata wydawnicza:: Rozkwitalska, M., Chmielecki, M., Przytuła, S., The Positives of Cross-cultural Interactions in Multinational Companies, "Actual Problems of Economics", 2014, 7(57), pp. 382-392
Opis:: The authors attempt to explore the positives of cross-cultural interactions in multinational companies (MNCs). The prior research has generally accentuated the problems in the relationship among foreigners and less effort has been made so far to examine the benefits of multiculturalism. Therefore, there is a need to fill in the gap identified above by providing the evidence that professional contacts with representatives from a different national cultural background may be very useful for both MNCs and individuals who are employed by them. The results of the authors' study suggest that the following major positives can be obtained due to cultural diversity, namely: 1) personal growth; 2) flexibility in working styles; 3) enhanced learning; 4) more perspectives, self-reflection; 5) individual benefits; 6) more effective communication; and finally 7) confrontation with stereotypes.
Narodowe Centrum Nauki
Małgorzata Rozkwitalska
Dostawca treści:: Repozytorium Centrum Otwartej Nauki

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Skocz do pozycji: 10.

Tytuł:: Informal Taxonomies of Charges of Correctional Facilities and Shelters for Juveniles Created by Personnel in the Context of Social Rehabilitation Interactions. Sociological Analysis of the Phenomenon
Autorzy:: Chomczyński, Piotr
Wydawca:: FUNDACJA PEDAGOGIUM
Opis:: The main aim of this paper is to draw attention to the phenomenon of creating informal taxonomies by the personnel of correctional institutions (ZP) and shelters for juveniles (SdN) towards charges in relation to social rehabilitation work. It discusses both the mechanisms of creating such classifications as well as the consequences associated with them. The article defends the thesis that this type of stigmatization is on the one hand a natural phenomenon, because it is based on the mechanism of analogy, to a large extent unconscious, typical for educational institutions, but on the other hand dependent in its form on the adopted style of institution management. It also discusses the problem of multiple consequences of taxonomies. The results presented in this paper are based on seven years qualitative research carried out in social rehabilitation centers of all types throughout Poland. The research applied the principle of triangulation in the scope of methods, the researcher and data. To analyze empirical data an interpretative paradigm was used, which enables to see the interactive nature of the formation of negative emotions and emotional work.
Piotr Chomczyński
Dostawca treści:: Repozytorium Centrum Otwartej Nauki

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