- Tytuł:
- Synthetic Organic Chemistry of α-Imino Ketones: A Graphical Review
- Autorzy:
-
Pareek, Abhishek
Yaragorla, Srinivasarao - Wydawca:
- Stuttgart: Thieme
- Cytata wydawnicza:
- SynOpen 2024; 08(04): 265-272. DOI: 10.1055/s-0040-1720150
- Opis:
- α-Imino ketones are traditionally synthesized through condensing simple and readily available α-keto aldehydes or 1,2-diketones with primary or secondary amines. They are structurally similar to many naturally occurring biological substances due to the presence of the imino group (–N=C–). Chemically, C-acylimines exhibit ambiphilic reactivity, making their synthetic chemistry particularly attractive and viable for the creation of various aza-cyclic and heterocyclic compounds, including their asymmetric counterparts. Consequently, numerous synthetic strategies have been developed starting from these building blocks. Herein, we provide a graphical review of state-of-the-art synthetic efforts over the past 20 years, focusing on the use of α-imino ketones (both cyclic and acyclic) for the synthesis of small molecules and complex systems.
- Dostawca treści:
- Repozytorium Centrum Otwartej Nauki
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