- Tytuł:
- Protective effects of quercetin on cadmium fluoride induced oxidative stress at different intervals of time in mouse liver
- Autorzy:
-
Zargar, Seema
Siddiqi, Nikhat
Al Daihan, Sooad
Wani, Tanveer - Tematy:
-
cadmium fluoride
quercetin
oxidative stress
flavonoids
histology
adverse effect - Pokaż więcej
- Data publikacji:
- 2015
- Powiązania:
- https://bibliotekanauki.pl/articles/1039092.pdf Link otwiera się w nowym oknie
- Źródło:
-
Acta Biochimica Polonica; 2015, 62, 2; 207-213
0001-527X - Pojawia się w:
- Acta Biochimica Polonica
- Opis:
- Quercetin, a member of the flavonoid family is a major antioxidant acquired in humans by food consumption, while Cadmium fluoride (CdF2) is one of the naturally occurring chemicals having adverse effects. The protective effect of quercetin on time dependent oxidative damage induced in mice liver by CdF2 was studied in the following groups of mice consisting of six mice each: (i) control group; (ii) mice treated with single i.p injection of 2 mg/kg bw CdF2 for 24 h; (iii) mice treated with single i.p injection of 2 mg/kg bw CdF2 for 48 h; (iv) mice treated with single i.p injection of quercetin (100 mg/kg bw); (v) mice treated with i.p injection of 100 mg/kg bw of quercetin followed by i.p injection of CdF2 (2 mg/kg bw) for 24 h; and (vi) mice treated with i.p injection of 100mg/kg bw of quercetin followed by CdF2 (2 mg/kg bw) for 48 h. Administration of quercetin two hours before CdF2 significantly reduced the biochemical alterations in reduced glutathione, ascorbic acid, lipid peroxidation, super oxide dismutase, catalase and total protein (p
- Dostawca treści:
- Biblioteka Nauki
Artykuł