Temat: bone tissue engineering

Skocz do pozycji: 1.

Tytuł:: Innovative macroporous chitosan/agarose matrix-based biomaterial for bone tissue engineering applications
Autorzy:: Kazimierczak, P.
Pałka, K.
Ginalska, G.
Przekora, A.
Tematy:: biomaterials
bone tissue engineering
scaffolds; Pokaż więcej
Data publikacji:: 2018
Powiązania:: https://bibliotekanauki.pl/articles/285776.pdf Link otwiera się w nowym oknie
Źródło:: Engineering of Biomaterials; 2018, 21, 148; 13
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Pojawia się w:: Engineering of Biomaterials
Dostawca treści:: Biblioteka Nauki

Artykuł

na półce

Skocz do pozycji: 2.

Tytuł:: Bioapatite made from chicken femur bone
Autorzy:: Supova, M.
Simha-Martynkova, G.
Sucharda, Z.
Suchy, T.
Tematy:: biomaterials
hydroxyapatite
bone tissue engineering; Pokaż więcej
Data publikacji:: 2011
Powiązania:: https://bibliotekanauki.pl/articles/283953.pdf Link otwiera się w nowym oknie
Źródło:: Engineering of Biomaterials; 2011, 14, no. 109-111 spec. iss.; 11-13
1429-7248
Pojawia się w:: Engineering of Biomaterials
Dostawca treści:: Biblioteka Nauki

Artykuł

na półce

Skocz do pozycji: 3.

Tytuł:: Evaluation of cellulose/hydroxyapatite scaffolds for bone tissue engineering: studies in vitro and in vivo
Autorzy:: Liesiene, J.
Baniukaitiene, O.
Daugela, P.
Pranskunas, M.
Juodzbalys, G.
Babenko, N.
Tematy:: bone tissue engineering
hydroxyapatite
cellulose; Pokaż więcej
Data publikacji:: 2016
Powiązania:: https://bibliotekanauki.pl/articles/284014.pdf Link otwiera się w nowym oknie
Źródło:: Engineering of Biomaterials; 2016, 19, 138; 73
1429-7248
Pojawia się w:: Engineering of Biomaterials
Dostawca treści:: Biblioteka Nauki

Artykuł

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Skocz do pozycji: 4.

Tytuł:: Mechanical properties of carbon/hydroxyapatite nonwovens for bone tissue engineering
Autorzy:: Rajzer, I.
Piekarczyk, W.
Grzybowska-Pietras, J.
Janicki, J.
Tematy:: nonwovens
bone tissue
bone tissue engineering
hydroxyapatite; Pokaż więcej
Data publikacji:: 2010
Powiązania:: https://bibliotekanauki.pl/articles/285172.pdf Link otwiera się w nowym oknie
Źródło:: Engineering of Biomaterials; 2010, 13, 93; 6-9
1429-7248
Pojawia się w:: Engineering of Biomaterials
Dostawca treści:: Biblioteka Nauki

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na półce

Skocz do pozycji: 5.

Tytuł:: Nanoparticles, nanofibres and their combinations in bone tissue engineering – a review
Autorzy:: Bacakova, L.
Tematy:: bone tissue engineering
nanoparticles
nanofibres; Pokaż więcej
Data publikacji:: 2011
Powiązania:: https://bibliotekanauki.pl/articles/284712.pdf Link otwiera się w nowym oknie
Źródło:: Engineering of Biomaterials; 2011, 14, no. 109-111 spec. iss.; 4-5
1429-7248
Pojawia się w:: Engineering of Biomaterials
Opis:: Nanostructured materials are considered as promising scaffolds for advanced tissue engineering. The reason is that the nanostructure of a material resembles the nanoarchitecture of the natural extracellular matrix (ECM), e.g., its organization into nanofibres, nanocrystals, nanosized folds of ECM molecules, etc. On nanostructured surfaces , the cell adhesion - mediating ECM molecules adsorb in an appropriate geometrical orientation which gives cell adhesion receptors access to specific sites in ECM molecules, such as amino acid sequences like Arg-Gly-Asp (RGD) , which serve as ligands for these receptors [1 - 3]. In addition, these materials enhance the adsorption of vitronectin, which is recognized preferentially by osteoblasts over other cell types [1 - 3]. Nanostructured materials have therefore been considered as suitable particularly for bone tissue engineering. Our studies have focused on carbon and hydroxy apatite nanoparticles as components of substrates for colonization with human bone - derived cells in vitro. Carbon nanoparticles, namely nanocrystalline diamond (NCD) and fullerenes C 60, have been used in the form of films deposited on carbon, glass, silicon and metallic substrates [3-4]. These films were o f continuous (NCD) or micropatterned (C 60 ) morphology , and have been intended for surface modifications of bone and dental implants [5], or for creating surfaces enabling regionally -selective cell adhesion and directed cell growth [6]. NCD films were also doped with boron, which resulted in improved adhesion, growth and osteogenic differentiation (measured by the production of collagen I, osteocalcin and alkaline phosphatase content) of human osteoblast-like M G 63 cells [7]. These beneficial effects can be explained by the increased electrical conductivity of boron-doped nanocrystalline diamond films, and can be further enhanced by active electric stimulation of cells. Some nanoparticles were also incorporated into polymeric matrices, e.g. foils of a terpolymer of polytetra fluoroethylene, poly vinyldi fluoride and poly- propylene ( carbon nanohorns, carbon nanotubes ) or nano fibres prepared by an electrospinning technique from polylactide, PLA (hydroxyapatite nanoparticles ) or poly( lactide-co-glycolide), PLGA (nanodiamond). All these composite substrates promoted the adhesion, growth and osteogenic differentiation of human osteoblast-like MG 63 cells in an extent similar to or even better than standard cell cultivation substrates , such as polystyrene dishes or microscopic glass coverslips. The adhesion and growth of MG 63 cells was particularly improved on the terpolymer of polytetrafluoroethylene, polyvinyldifluoride and polypropylene enriched with 4 wt. % of single-wall carbon nanohorns or multi-wall carbon nanotubes [3, 4]. The osteogenic differentiation of MG 63 cells (measured by concentration of osteocalcin) was enhanced on nanofibrous polylactide scaffolds loaded with 15 wt % of hydroxyapatite. On PLGA nanofibrous scaffolds loaded with approx. 23 wt. % of diamond particles, the number of initially adhering MG 63 cells on day 1 after seeding and the following growth dynamics of the cell swere similar to the values on pure PLGA scaffolds [8]. However, the cells on PLGA meshes reinforced with nanodiamond formed larger and more numerous talin-containing focal adhesion plaques. In addition, these plaques in cells on PLGA-nanodiamond scaffolds were localized not only at the cell periphery but also in the central part of the cells (FIG (1). Thus, it can be concluded that nanoparticle-modified materials are more promising than their non-modified counterparts f or colonization with bone cells, f or construction o f bone implants and f or bone t issue engineering.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 6.

Tytuł:: The promise of composite polymers for bone tissue engineering
Autorzy:: Amedee, J.
Tematy:: polymers
bone tissue engineering
composite; Pokaż więcej
Data publikacji:: 2016
Powiązania:: https://bibliotekanauki.pl/articles/284997.pdf Link otwiera się w nowym oknie
Źródło:: Engineering of Biomaterials; 2016, 19, 138; 7
1429-7248
Pojawia się w:: Engineering of Biomaterials
Opis:: The repair of bone defects is of particular interest for orthopaedic, oral, maxillofacial, and dental surgery. Bone loss is conventionally reconstructed by bone grafting. Depending on size and location of the defect, this method has limits and risks. In addition, in the context of reconstruction of the craniofacial skeleton after radiation therapy, we need to improve therapeutic options for patients suffering from such disastrous sequelae of radiation therapy. While the use of BMPs has been approved for bone regeneration applications, their use is contraindicated in a carcinological context, due to concerns that these anabolic growth factors may contribute to tumor cell proliferation. Moreover, the main limitations are to regenerate a functional vasculature [1] and to restore bone innervation that also played a major role for bone tissue regeneration [2,3]. In such context, biomaterials such as calcium phosphate matrices, free of reparative cells, cannot offer sufficient potential for supporting especially vascularization of newly formed bone. Polymers and mainly composite based-polysaccharides, because of their versatility, their possible supplementation with a mineral phase (i.e hydroxyapatite particles), have immense potential for mimicking bone tissue, by trapping osteogenic and angiogenic factors and then promoting both osteogenesis and angiogenesis [4,5]. The other challenge in the field of bone tissue engineering is to favour anchorage of sensory neurons within 3D matrices that could produce neurotrophic factors [6], activate the coupling of osteogenesis and angiogenesis. Here, we will describe a cell-free approach for bone tissue engineering [7] using injectable composite polymers, their in vitro and in vivo validation in preclinical models from small to large animals. We will also show how composite polymer chemistry can also favour cell interactions between mesenchymal stem cells, endothelial cells and stimulate bone tissue regeneration.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 7.

Tytuł:: Co-polymeric biomaterials for bone tissue engineering
Autorzy:: Chatzinikolaidou, M.
Kaliva, M.
Papadimitriou, L.
Georgopoulou, A.
Mygdali, .
Vamvakaki, M.
Tematy:: bone tissue engineering
biomaterials
biodegradation; Pokaż więcej
Data publikacji:: 2017
Powiązania:: https://bibliotekanauki.pl/articles/285357.pdf Link otwiera się w nowym oknie
Źródło:: Engineering of Biomaterials; 2017, 20, no. 143 spec. iss.; 6
1429-7248
Pojawia się w:: Engineering of Biomaterials
Dostawca treści:: Biblioteka Nauki

Artykuł

na półce

Skocz do pozycji: 8.

Tytuł:: Structural variability of lyophilized collagen-based scaffolds: micro-CT 3D analysis
Autorzy:: Bartos, M.
Suchy, T.
Spanko, M.
Foltan, R.
Tematy:: bone tissue engineering
scaffolds
regeneration; Pokaż więcej
Data publikacji:: 2018
Powiązania:: https://bibliotekanauki.pl/articles/286100.pdf Link otwiera się w nowym oknie
Źródło:: Engineering of Biomaterials; 2018, 21, 148; 24
1429-7248
Pojawia się w:: Engineering of Biomaterials
Dostawca treści:: Biblioteka Nauki

Artykuł

na półce

Skocz do pozycji: 9.

Tytuł:: Electrospun biomimetic resorbable scaffold
Autorzy:: Rajzer, I.
Piekarczyk, W.
Kwiatkowski, R.
Biniaś, W.
Janicki, J.
Tematy:: bone tissue engineering
scaffolds
resorbable materials; Pokaż więcej
Data publikacji:: 2010
Powiązania:: https://bibliotekanauki.pl/articles/285153.pdf Link otwiera się w nowym oknie
Źródło:: Engineering of Biomaterials; 2010, 13, no. 99-101; 13-15
1429-7248
Pojawia się w:: Engineering of Biomaterials
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 10.

Tytuł:: The influence of mineralization conditions on the effectiveness of enzymatic mineralization of hydrogels
Autorzy:: Pietryga, K.
Reczyńska, K.
Pamuła, E.
Tematy:: enzymatic mineralization
hydrogels
bone tissue engineering; Pokaż więcej
Data publikacji:: 2015
Powiązania:: https://bibliotekanauki.pl/articles/285814.pdf Link otwiera się w nowym oknie
Źródło:: Engineering of Biomaterials; 2015, 18, 131; 2-7
1429-7248
Pojawia się w:: Engineering of Biomaterials
Opis:: Polysaccharide hydrogels are widely used in food industry and medicine. Gellan gum (GG) recently gained a lot of attention as a promising material for tissue regeneration proposes due to its excellent biocompatibility and similarity to natural extracellular matrix. However, in unmineralized form it is not suitable for bone tissue engineering because of weak mechanical properties. Enzymatic mineralization (e.g. using alkaline phosphatase – ALP) is one of the methods of calcifying of hydrogels and it resembles natural processes occurring during bone healing. The aim of this research was to investigate mineralization of hydrogels and to improve properties of gellan gum scaffolds by adjusting processing conditions. Since ALP does not form with GG covalent bonds, during incubation in mineralization medium (solution of calcium glycerophosphate - CaGP) it is diffusing from the samples. Therefore, mineralization effectiveness depends on the interplay between incoming CaGP and outgoing ALP molecules. We hypothesize that better CaGP availability, especially in the first hours of incubation, can result in more effective and homogenous precipitation of calcium phosphates (CaP) in GG samples. To this end, samples with different GG and ALP concentration were subjected to two different mineralization regimes (more and less frequent CaGP exchanges). We proved that better CaGP availability (more frequent CaGP exchange) resulted in better mechanical properties (Young’s modulus) and more effective mineral formation (higher dry mass percentage) of the samples compared to the same samples mineralized with lower accessibility of CaGP. This may be related to the fact, that in presence of fresh organic substrates, more CaP are formed in the outer parts of the samples at the beginning of the process, that limit ALP diffusion and allow more uniform mineralization.
Dostawca treści:: Biblioteka Nauki

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