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Tytuł:
Automatic Extraction of the Pelvicalyceal System for Preoperative Planning of Minimally Invasive Procedures
Autorzy:
Heryan, K.
Skalski, A.
Jakubowski, J.
Drewniak, T.
Gajda, J.
Tematy:
pelvicalyceal system segmentation
kidney segmentation
kidney compartments
Computed Tomography (CT)
kidney cancer
Pokaż więcej
Data publikacji:
2017
Powiązania:
https://bibliotekanauki.pl/articles/220364.pdf  Link otwiera się w nowym oknie
Źródło:
Metrology and Measurement Systems; 2017, 24, 1; 3-18
0860-8229
Pojawia się w:
Metrology and Measurement Systems
Opis:
Minimally invasive procedures for the kidney tumour removal require a 3D visualization of topological relations between kidney, cancer, the pelvicalyceal system and the renal vascular tree. In this paper, a novel methodology of the pelvicalyceal system segmentation is presented. It consists of four following steps: ROI designation, automatic threshold calculation for binarization (approximation of the histogram image data with three exponential functions), automatic extraction of the pelvicalyceal system parts and segmentation by the Locally Adaptive Region Growing algorithm. The proposed method was applied successfully on the Computed Tomography database consisting of 48 kidneys both healthy and cancer affected. The quantitative evaluation (comparison to manual segmentation) and visual assessment proved its effectiveness. The Dice Coefficient of Similarity is equal to 0.871 ± 0.060 and the average Hausdorff distance 0.46 ± 0.36 mm. Additionally, to provide a reliable assessment of the proposed method, it was compared with three other methods. The proposed method is robust regardless of the image acquisition mode, spatial resolution and range of image values. The same framework may be applied to further medical applications beyond preoperative planning for partial nephrectomy enabling to visually assess and to measure the pelvicalyceal system by medical doctors.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Surgical Procedures Not Connected with Transplantation in Patients After Kidney or Kidney and Pancreas Transplant with Stable Function of Graft
Autorzy:
Kałuża, Bernadetta
Ziobrowski, Ireneusz
Durlik, Marek
Tematy:
kidney transplantation
kidney and pancreas transplantation
complication
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Data publikacji:
2012-04-01
Powiązania:
https://bibliotekanauki.pl/articles/1396724.pdf  Link otwiera się w nowym oknie
Źródło:
Polish Journal of Surgery; 2012, 84, 4; 196-201
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Opis:
The aim of the study was to evaluate complication during and after surgical procedure without connection with transplantation among patients after kidney, kidney and pancreas transplantation with stable function of graft.Material and methods. 54 patients underwent 62 surgical procedures without connection with transplantation procedure. Main characteristic: standard immunosuppressive treatment, main age 51.1±13.95 years, men 77.4%, hospitalization time 5.27±3.31 day, group 1 - 55 procedures among patients after kidney transplantation, group 2 - 7 procedure among patients after kidney and pancreas transplantation.Results. Procedures from general surgery comprised 60% [cholecystectomy 19 (51%), left hemicolectomy 1 (3%), esophagus removal 1 (3%), hernia repair 8 (22%), nefrectomy 3 (8%), pancreas transplantation in patients with functional renal graft 1 (3%), laparotomy 4 (11%), vascular surgery 27% (correction of arteriovenosus fistula 13 (76%), by-pass surgery 1 (6%), embolectomy 1 (6%), implantation of aortal - iliac stentgraft 1 (6%), surgery of iliac artery 1 (6%)]. There has been no difference between parameters measured before and after procedure: creatinine (p=0.93), GFR (p=0.07), urea (p=0.25), glycaemia (p=0.322), glycated hemoglobin (p=0.3), C-peptide (p=0.3). In both groups were no differences in levels of creatinine (p=0.78) and urea (p=0.23), measured in the next years after surgical procedure. Mortality 0%, lost of graft 0%, in - hospital morbidity 10 (16.2%) (hematoma 1.6%, endocavitary electrode 1.6%, wound healing defect 16.2%). Morbidity in group 1 - 12.7%, group 2 - 48.8%, p=0.04.Conclusions. Surgical procedures performed in a specialist center do not impaire prognosis of patients with stable function of graft, after kidney, kidney and pancreas transplantation.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Atorvastatin improves tubular status in non-diabetic patients with chronic kidney disease - placebo controlled, randomized, cross-over study
Autorzy:
Renke, Marcin
Tylicki, Leszek
Rutkowski, Przemysław
Neuwelt, Alexander
Larczyński, Wojciech
Ziętkiewicz, Marcin
Aleksandrowicz, Ewa
Łysiak-Szydłowska, Wiesława
Rutkowski, Bolesław
Tematy:
proteinuria
kidney
tubular injury
chronic kidney disease
Atorvastatin
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Data publikacji:
2010
Powiązania:
https://bibliotekanauki.pl/articles/1040322.pdf  Link otwiera się w nowym oknie
Źródło:
Acta Biochimica Polonica; 2010, 57, 4; 547-552
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Opis:
Background. There is evidence that dyslipidemia is associated with chronic kidney disease (CKD) and it has been implicated in the progression of renal damage. Optimal management of dyslipidemia should therefore lead to renal benefits. A number of experimental models demonstrate a beneficial effect of statins in ameliorating renal damage. However, the exact mechanism by which statins protect against renal damage remains unclear. Methods. In a placebo-controlled, randomized, cross-over study we evaluated the influence of atorvastatin (ATO) 40 mg/day added to the renin-angiotensin-aldosterone systeme (RAAS) blockade on proteinuria and surrogate biomarkers of tubular damage or injury in 14 non-diabetic patients with proteinuria (0.4-1.8 g per 24 h) with normal or declined kidney function (eGFR 55-153 ml/min). In the eight-week run-in period, therapy using angiotensin converting enzyme inhibitors (ACEI) and/or angiotensin II subtype 1 receptor antagonists (ARB) was adjusted to achieve a blood pressure below 130/80 mm Hg. Next, patients were randomly assigned to one of two treatment sequences: ATO/washout/placebo or placebo/washout/ATO. Clinical evaluation and laboratory tests were performed at the randomization point and after each period of the study. The primary end point of this study was a change in proteinuria measured as 24-h urine protein excretion (DPE). Secondary end points included urine N-acetyl-β-d-glucosaminidase (NAG) and α1-microglobulin (α1m) excretion. Results. The ATO therapy significantly reduced urine excretion of α1m (p=0.033) and NAG (p=0.038) as compared to placebo. There were no differences in proteinuria, blood pressure, eGFR and serum creatinine between the ATO and placebo groups. Conclusion. Atorvastatin treatment is safe and improves biomarkers of tubular damage or injury in non-diabetic patients with CKD.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of renal function in primary care
Autorzy:
Musiałowska, B.
Rudzińska, M.
Koc-Żórawska, E.
Żórawski, M.
Tematy:
chronic kidney disease
acute kidney injury
Primary Care
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Data publikacji:
2018
Powiązania:
https://bibliotekanauki.pl/articles/1918735.pdf  Link otwiera się w nowym oknie
Źródło:
Progress in Health Sciences; 2018, 8(2); 202-205
2083-1617
Pojawia się w:
Progress in Health Sciences
Opis:
Evaluation of renal function is one of the primary tools used in treatment and monitoring kidney injury such as acute kidney injury (AKI) or chronic kidney disease (CKD) in Primary Care patients. Accompanying chronic diseases also have an impact on the assessment of renal function, treatment monitoring and adjustment of drug doses.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sonographic assessment of the prevalence and evolution of fluid collections as a complication of kidney transplantation
Ultrasonograficzna ocena występowania i ewolucji zbiorników płynowych jako powikłania procedury transplantacji nerki
Autorzy:
Kuczyńska, Maryla
Piasek, Ewa
Światłowski, Łukasz
Kuklik, Ewa
Sobstyl, Jan
Drelich-Zbroja, Anna
Słomka, Tomasz
Pyra, Krzysztof
Furmaga, Olga
Szczerbo-Trojanowska, Małgorzata
Tematy:
kidney transplantation
Pokaż więcej
Data publikacji:
2018
Powiązania:
https://bibliotekanauki.pl/articles/1033110.pdf  Link otwiera się w nowym oknie
Źródło:
Journal of Ultrasonography; 2018, 18, 73; 126-132
2451-070X
Pojawia się w:
Journal of Ultrasonography
Opis:
Aim of the study: The aim of this study is to assess the prevalence and evolution of perirenal fluid collections in a group of 488 patients who have undergone kidney transplantation. Material and methods: Sonographic documentation of 488 deceased-donor kidney recipients was evaluated for the prevalence of perirenal fluid collections and their evolution in time, depending on selected demographic features of the patients, time of detection, initial dimensions and precise position of the collection relative to the kidney and the location of the transplanted organ in the right or left iliac fossa. The collected data were used for statistical analysis to determine the strength of the potential relationships. Results: In 146 out of 488 subjects perirenal fluid collections were found. In 1/3 of the patients more than one fluid collection was diagnosed. Over 40% of fluid collections were detected within 10 days from the date of the first scan and 24.11% were detected within 10–20 days from the date of the first scan. The majority of fluid collections were located near the lower pole of the kidney. Perihilar collections were the least common. Collections encapsulating the kidney and subcutaneous collections were the largest in size on average. A statistically significant difference between the size of collections located on the surface and the size of those located near the upper pole of the transplanted kidney was demonstrated. However, no correlation was proven to exist between the persistence of the fluid collection and its position relative to the transplanted kidney and its initial size. Conclusions: The correct evaluation of a fluid collection’s dynamics of development and nature requires periodic follow-up of the recipient, preferably in a single clinical center. Ultrasonography is an inexpensive, non-invasive and repeatable method for the determination of the presence of fluid collections. However, the decision whether treatment is necessary requires the sonographic image to be compared with the laboratory signs of inflammation and biochemical analysis of the contents of fluid collections.
Cel pracy: Celem niniejszego opracowania jest ocena występowania i ewolucji okołonerkowych zbiorników płynowych w grupie 488 pacjentów poddanych operacji transplantacji nerki. Materiał i metody: Dokumentacja ultrasonograficzna 488 biorców nerek od dawców zmarłych została poddana ocenie pod kątem częstości występowania okołonerkowych zbiorników płynowych i ich ewolucji w czasie, w zależności od wybranych cech demograficznych pacjenta, czasu wykrycia, początkowych rozmiarów i dokładnej lokalizacji zbiornika względem nerki oraz umiejscowienia przeszczepionego narządu – w prawym lub lewym dole biodrowym. Zgromadzone dane wykorzystano do analizy statystycznej w celu określenia siły ewentualnych zależności. Wyniki: U 146 na 488 badanych stwierdzono obecność okołonerkowych zbiorników płynowych, przy czym u niemal 1/3 pacjentów zdiagnozowano więcej niż jeden zbiornik. Przeszło 40% zbiorników wykryto przed upływem 10 dni od daty pierwszego badania,a 24,11% –w okresie 10–20 dni od daty pierwszego badania. Najwięcej kolekcji płynowych było zlokalizowanychw okolicy bieguna dolnego nerki. Najrzadziej występowały zbiorniki okołownękowe. Największy średni rozmiar osiągały zbiorniki opłaszczające nerkęi leżące podskórnie. Wykazano istotną statystycznie różnicę pomiędzy wymiarami zbiorników zlokalizowanych powierzchniowo orazw okolicy bieguna górnego przeszczepionej nerki. Nie dowiedziono jednak istnienia korelacji pomiędzy trwałością zbiornikaa jego lokalizacją względem przeszczepionej nerki lub początkowym wymiarem. Wnioski: Prawidłowa ocena dynamiki rozwojui charakteru zbiornika płynowego wymaga okresowej kontroli biorcy,najlepiejw jednym ośrodku klinicznym. Ultrasonografia jest tanią, nieinwazyjnąi powtarzalną metodą oceny występowania kolekcji płynowych. Decyzjao potrzebie leczenia wymaga jednak odniesienia obrazu sonograficznego do parametrów zapalnych oraz wyników analiz biochemicznych zawartości zbiorników.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of pentoxifylline on proteinuria, markers of tubular injury and oxidative stress in non-diabetic patients with chronic kidney disease - placebo controlled, randomized, cross-over study
Autorzy:
Renke, Marcin
Tylicki, Leszek
Rutkowski, Przemysław
Knap, Narcyz
Ziętkiewicz, Marcin
Neuwelt, Alexander
Aleksandrowicz, Ewa
Łysiak-Szydłowska, Wiesława
Woźniak, Michał
Rutkowski, Bolesław
Tematy:
pentoxifylline
oxidative stress
kidney
chronic kidney disease
proteinuria
tubular injury
Pokaż więcej
Data publikacji:
2010
Powiązania:
https://bibliotekanauki.pl/articles/1040438.pdf  Link otwiera się w nowym oknie
Źródło:
Acta Biochimica Polonica; 2010, 57, 1; 119-123
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Opis:
Background: Inhibition of the renin-angiotensin-aldosterone system (RAAS) with angiotensin converting enzyme inhibitors (ACEI) and/or angiotensin II subtype 1 receptor antagonists (ARB) is a common strategy used in the management of patients with chronic kidney disease (CKD). However, there is no universal therapy that can stop progression of CKD. Pentoxifylline (PTE) is a non-specific phosphodiesterase inhibitor with anti-inflammatory properties. It has been reported to have promising effects in CKD treatment. Methods: In a placebo-controlled, randomized, cross-over study we evaluated the influence of PTE (1200 mg/day) added to RAAS blockade on proteinuria, surrogate markers of tubular injury and oxidative stress-dependent products in 22 non-diabetic patients with proteinuria (0.4-4.3 g per 24h) with normal or declined kidney function [eGFR 37-178 mL/min]. In an eight-week run-in period, therapy using ACEI and/or ARB was adjusted to achieve a blood pressure below 130/80 mm Hg. Next, patients were randomly assigned to one of two treatment sequences: PTE/washout/placebo or placebo/washout/PTE. Clinical evaluation and laboratory tests were performed at the randomization point and after each period of the study. Results: The PTE therapy reduced proteinuria (by 26%) as compared to placebo. There were no differences in α1-microglobulin, urine excretion of N-acetyl-β-d-glucosaminidase (NAG), hsCRP, the urinary excretion of 15-F2t-isoprostane, blood pressure (BP), eGFR and serum creatinine between the PTE and placebo groups. Conclusion: Pentoxifylline may decrease proteinuria in non-diabetic patients with CKD.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Uromodulin – biomarker of renal function with promising clinical application
Autorzy:
Chojęta, D.
Kozioł, M.M.
Smarz-Widelska, I.
Tematy:
Tamm-Horsfall protein
chronic kidney disease
acute kidney failure
Umod
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Data publikacji:
2020
Powiązania:
https://bibliotekanauki.pl/articles/2087806.pdf  Link otwiera się w nowym oknie
Źródło:
Medical Science Pulse; 2020, 14, 3; 84-90
2544-1558
2544-1620
Pojawia się w:
Medical Science Pulse
Opis:
Uromodulin (also known as Tamm-Horsfall protein) is a glycoprotein produced exclusively in the kidneys, mainly in the epithelial cells of the thick ascending limb of the loop of Henle. Under physiological conditions, it is the most abundant urinary protein. A small proportion is released into the renal interstitium and then into the blood, where it can be detected and used as a potential parameter of renal function. Uromodulin has numerous physiological roles and potential pathogenetic significance, including providing protection against urinary tract infections and the formation of urinary deposits, as well as being involved in the immunomodulatory functions and regulation of water and electrolyte balance by the kidneys. Unlike classic renal markers (such as creatinine), uromodulin levels decrease with progressive renal dysfunction. A significant advantage of this parameter is therefore the detectable changes in concentration at the early stages of development of chronic kidney disease. In addition, assessment in clinical materials, such as urine and blood, is relatively simple by immunoenzymatic methods. It is evident that the quantitative determination of uromodulin in blood serum is associated with a lower risk of laboratory error and has a better correlation with renal function. Based on previous studies, Tamm-Horsfall protein / uromodulin can be considered a valuable parameter for standard diagnostics of kidney function and renal diseases. It appears that no other marker is currently able to reflect the integrity and functional state of the renal tubules as sensitively as uromodulin. Due to the potential of this parameter, the article presents and overview of the current information available about uromodulin, as well as the available diagnostic tests and the frequency of their use in clinical practice.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Malignancy-associated kidney disease
Autorzy:
Kozłowska, K.
Małyszko, J.
Tematy:
malignancy
acute kidney injury
chronic kidney injury
glomerulopathy
thrombotic microangiopathy
Pokaż więcej
Data publikacji:
2016
Powiązania:
https://bibliotekanauki.pl/articles/1917719.pdf  Link otwiera się w nowym oknie
Źródło:
Progress in Health Sciences; 2016, 6(1); 183-187
2083-1617
Pojawia się w:
Progress in Health Sciences
Opis:
Malignancy or its treatment affect kidney in several ways. The most common are acute kidney injury and chronic kidney disease. Other form of kidney diseases can also be present such as nephrotic syndrome, tubulointerstitial nephritis, thrombotic microangipathy etc. In addition, electrolyte abnormalities such as hypercalcemia, hyponatremia and hypernatremia, hypokalemia and hyperkalemia, and hypomagnesemia. are observed. Treatment of malignancy associated kidney disease is usually symptomatic. Cessation of the offending agent or other supportive measures if needed i.e. renal replacement therapy are also implemented.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Red blood cell and plasma glutathione peroxidase activities and selenium concentration in patients with chronic kidney disease: A review
Autorzy:
Zachara, Bronisław
Gromadzińska, Jolanta
Wąsowicz, Wojciech
Zbróg, Zbigniew
Tematy:
hemodialysis
selenium
kidney transplantation
glutathione peroxidase
chronic kidney disease
antioxidants
plasma
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Data publikacji:
2006
Powiązania:
https://bibliotekanauki.pl/articles/1041155.pdf  Link otwiera się w nowym oknie
Źródło:
Acta Biochimica Polonica; 2006, 53, 4; 663-677
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Opis:
The metabolism of oxygen in aerobic organisms leads to generation of reactive oxygen species (ROS). These entities are able to oxidize almost all classes of macromolecules, including proteins, lipids and nucleic acids. The physiological level of ROS is usually regulated by antioxidant defense mechanisms. There are at least three groups of antioxidant enzymes: superoxide dismutases, catalases and glutathione peroxidases (GSH-Pxs) which neutralize ROS. The trace elements (copper, zinc and selenium) bound to the active sites of the above listed enzymes play an important role in the antioxidant defense system. In mammals, a major function of selenium (Se) and Se-dependent GSH-Pxs is to protect cells from oxidative stress. Selenium concentrations and GSH-Px activities are altered in blood components of chronic kidney disease (CKD) patients. The Se level is frequently lower than in healthy subjects and the concentration very often decreases gradually with advancing stage of the disease. Studies on red cell GSH-Px activity in CKD patients reported its values significantly lower, significantly higher and lower or higher, but not significantly as compared with healthy subjects. On the other hand, all authors who studied plasma GSH-Px activity have shown significantly lower values than in healthy subjects. The degree of the reduction decreases gradually with the progression of the disease. High inverse correlations were seen between plasma GSH-Px activity and creatinine level. A gradual decrease in plasma GSH-Px activity in CKD patients is due to the fact that this enzyme is synthesized predominantly in the kidney and thus the impairment of this organ is the cause of the enzyme's lower activity. Se supplementation to CKD patients has a slightly positive effect in the incipient stage of the disease, but usually no effect was observed in end-stage CKD. Presently, kidney transplantation is the only treatment that may restore plasma Se level and GSH-Px activity in patients suffering from end-stage CKD. A few studies have shown that in kidney recipients, plasma Se concentration and GSH-Px activity are restored to normal values within a period of 2 weeks to 3 months following surgery and thus it can be acknowledged that Se supplementation to those patients has a positive effect on plasma GSH-Px activity.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wyniki leczenia operacyjnego raka nerki w I Klinice Urologii Uniwersytetu Medycznego w Łodzi w latach 2004–2010
Results of surgical treatment of kidney cancer in the Department of Urology, Medical University of Lodz in 2004–2010
Autorzy:
Kierstan, Andrzej
Jabłonowski, Zbigniew
Sosnowski, Marek
Tematy:
rak nerki
leczenie operacyjne
kidney cancer
surgical treatment of kidney cancer
Pokaż więcej
Data publikacji:
2016
Powiązania:
https://bibliotekanauki.pl/articles/1032607.pdf  Link otwiera się w nowym oknie
Źródło:
Folia Medica Lodziensia; 2016, 43, 1; 53-68
0071-6731
Pojawia się w:
Folia Medica Lodziensia
Opis:
Introduction. Aim of the study: The only effective treatment method for all forms of the kidney cancer is surgery with possible subsequent institution of neoadjuvant treatment. The standard management involves nephrectomy with or without lymphadenectomy and adrenalectomy. In patients with kidney tumors up to 4 cm in diameter, surgical procedures saving the renal parenchyma (Nephron-Sparing Surgery – NSS) are currently performed. The objective was the retrospective analysis of the treatment results obtained in renal cancer patients who had undergone surgical procedures. The results of the treatment following nephrectomy performed from transperitoneal and retroperitoneal approach were compared with those obtained after NSS type procedures. Material and methods: The study was carried out in 238 patients: 107 women and 131 men with kidney cancer, operated on in the years 2004 – 2010. In 15 patients distant metastases were found. The nephrectomy was performed in 69 patients from transperitoneal access and in 105 patients from retroperitoneal access with NSS procedures in 55 patients. The transperitoneal approach was used in patients with large tumors ranging > 6 cm size. Other patients were operated on with lumbar access, also those with tumors < 4 cm, since that approach was used for NSS procedures. The intraoperative and postoperative period, the duration of the surgery, complications, hospitalization time, analgesic treatment and overall survival were evaluated. Results: The operated patients were hospitalized for 11 days on the average, and the mean time of the surgical procedure was ca. 168 minutes. Intraoperative blood loss during most of the performed procedures was without clinical significance but the largest blood loss during the operation was reported in the patients with kidney tumors > 10 cm during transperitoneal access surgery. The blood loss was compensated in 33 cases by the administration of RBC preparations in 21.74% of the patients after transperitoneal access surgeries and 10.65% of those after lumbar access. Retroperitoneal access was associated with the use of larger quantities of analgesic medications in the postoperative period. Histopathological investigations resulted with clear cell carcinoma in 85% of the patients, in other 15% of the cases, most commonly diagnosed with chromophobe and papillary carcinomas. The malignancy grade of RCC according to Fuhrman scale; Fuhrman 1 – 7.98%, Fuhrman 2 – 61.38%, Fuhrman 3 – 9.66%, Fuhrman 4 – 5.88%. Fuhrman grades 3 and 4 were, however, more common in the patients with the big tumors undergoing transperitoneal access. The local advancement of the removed kidney tumors according to TNM classification: stage pT1 in 156 patients, stage pT2 in 52 and pT3 in 1 patient. The distribution of diagnoses and staging was similar for both surgical approaches. The results of kidney cancer treatment were reflected by the assessment of 5–year survival of the patients. Such analysis was possible only in the subgroup of 115 patients who had undergone the surgery in the years 2004 – 2007. The obtained data indicated the overall 5–year survival rate amounting to 58.3% of the reviewed subgroup, whereas 48 patients, i.e. 41.7% died. The causes of death were not possible to know. It is noteworthy that the group of deaths included all the patients operated on at the metastatic stage of the disease. Conclusions: In large renal tumors > 6 cm size, transperitoneal access nephrectomy was preferred. In the remaining patients lumbar access procedures were performed, including kidney-sparing surgery. Fuhrman grade 3 and 4 clear cell tumors are predominant in the patients operated on with transperitoneal access. The number of intra- and postoperative complications is similar in both groups. The use of transperitoneal access is associated with an increase in the amount of analgesics administered in the postoperative course, longer duration of the surgical procedure and longer hospitalization time. The overall 5–year survival rate for the group of 115 patients operated on in the years 2004–2007 was 58.3%.
Dostawca treści:
Biblioteka Nauki
Artykuł

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