Wszystkie pola: Pelosini, Matteo

Skocz do pozycji: 1.

Artykuł

na półce

Skocz do pozycji: 2.

Tytuł:: A polygenic risk score for multiple myeloma risk prediction
Autorzy:: Reis, Rui Manuel
Canzian, Federico
Butrym, Aleksandra
Kadar, Katalin
Campa, Daniele
Piredda, Chiara
Kruszewski, Marcin
Marques, Herlander
Sainz, Juan
Zaucha, Jan Maciej
Avet-Loiseau, Herve
Tomczak, Waldemar
Raźny, Małgorzata
Vangsted, Annette Juul
Petrini, Mario
Orciuolo, Enrico
Zawirska, Daria
Abildgaard, Niels
Andersen, Vibeke
Andersen, Niels Frost
Druzd-Sitek, Agnieszka
Nagler, Arnon
Rymko, Marcin
Suska, Anna
Wątek, Marzena
Gemignani, Federica
Subocz, Edyta
Buda, Gabriele
Beider, Katia
Pelosini, Matteo
Mazur, Grzegorz
Dudziński, Marek
Minvielle, Stephane
Vogel, Ulla
Varkonyi, Judit
Dumontet, Charles
Jurczyszyn, Artur
Macauda, Angelica
Jamroziak, Krzysztof
Lesueur, Fabienne
Dostawca treści:: Repozytorium Uniwersytetu Jagiellońskiego

Artykuł

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Skocz do pozycji: 3.

Tytuł:: Genetically determined telomere length and multiple myeloma risk and outcome
Autorzy:: Watek, Marzena
Dudziński, Marek
Ebbesen, Lene Hyldahl
Markiewicz, Mirosław
Mazur, Grzegorz
Jurczyszyn, Artur
Avet-Loiseau, Herve
Karlin, Lionel
Vangsted, Annette Juul
Gruenpeter, Karolina
Iskierka-Jażdżewska, Elżbieta
Druzd-Sitek, Agnieszka
Taszner, Michał
Sarasquete, Maria Eugenia
Rymko, Marcin
Giaccherini, Matteo
Garcia-Sanz, Ramon
Kruszewski, Marcin
Orciuolo, Enrico
Jamroziak, Krzysztof
Zawirska, Daria
Pelosini, Matteo
Marques, Herlander
Beider, Katia
Martinez-Lopez, Joaquín
Moreno, Victor
Andersen, Vibeke
Lesueur, Fabienne
Kadar, Katalin
Stępień, Anna
Campa, Daniele
Raźny, Małgorzata
Butrym, Aleksandra
Tomczak, Waldemar
Suska, Anna
Demangel, Delphine
Macauda, Angelica
Alonso, M. Henar
Nagler, Arnold
Gemignani, Federica
Buda, Gabriele
Jacobsen, Svend Erik Hove
Subocz, Edyta
Varkonyi, Judit
Abildgaard, Niels
Reis, Rui Manuel
Canzian, Federico
Sainz, Juan
Dumontet, Charles
Dostawca treści:: Repozytorium Uniwersytetu Jagiellońskiego

Artykuł

na półce

Skocz do pozycji: 4.

Tytuł:: Common gene variants within 3-untranslated regions as modulators of multiple myeloma risk and survival
Autorzy:: Reis, Rui Manuel
Kadar, Katalin
Butrym, Aleksandra
Silvestri, Roberto
Canzian, Federico
Moreno, Victor
Campa, Daniele
Kruszewski, Marcin
Ostrovsky, Olga
Marques, Herlander
Watek, Marzena
Sainz, Juan
Ter Horst, Rob
Zaucha, Jan Maciej
Grząśko, Norbert
Avet-Loiseau, Herve
Garcia-Sanz, Ramon
Landi, Stefano
Jurczyszyn, Artur
Raźny, Małgorzata
Facioni, Maria Sole
Morani, Federica
Calvetti, Diego
Vangsted, Annette Juul
Rybicka, Malwina
Zawirska, Daria
Sarasquete, Maria Eugenia
Andersen, Vibeke
Druzd-Sitek, Agnieszka
Li, Yang
Nagler, Arnon
Rymko, Marcin
Laseueur, Fabienne
Subocz, Edyta
Stępień, Anna
Gemignani, Federica
Iskierka-Jazdzewska, Elzbieta
Martinez-Lope, Joaquin
Beider, Katia
Hove Jacobsen, Svend Erik
Pelosini, Matteo
Mazur, Grzegorz
Szombath, Gergely
Dudziński, Marek
Maccari, Giuseppe
Netea, Mihai G.
Jerez, Andres
Vogel, Ulla
Varkonyi, Judit
Dumontet, Charles
Krawczyk-Kulis, Malgorzata
Melaiu, Ombretta
Macauda, Angelica
Jamroziak, Krzysztof
Dostawca treści:: Repozytorium Uniwersytetu Jagiellońskiego

Artykuł

na półce

Skocz do pozycji: 5.

Tytuł:: Expression quantitative trait loci of genes predicting outcome are associated with survival of multiple myeloma patients
Autorzy:: Giles, Graham G.
Ziv, Elad
Clay-Gilmou, Alyssa I.
Dudziński, Marek
Ebbesen, Lene Hyldahl
Markiewicz, Mirosław
Mazur, Grzegorz
Martinez-Lopez, Joaquin
Grzasko, Norbert
Jurczyszyn, Artur
Vangsted, Annette Juul
Norman, Aaron D.
Druzd-Sitek, Agnieszka
Brown, Elizabeth E.
Iskierka-Jazdzewska, Elzbieta
Andersen, Niels Frost
Rymko, Marcin
Milne, Roger L.
Garcia-Sanz, Ramon
Kruszewski, Marcin
Jamroziak, Krzysztof
Zawirska, Daria
Pelosini, Matteo
Barington, Torben
Marques, Herlander
Camp, Nicola J.
Vachon, Celine M.
Waller, Rosalie G.
Piredda, Chiara
Campa, Daniele
Prejzner, Witold
Raźny, Małgorzata
Tomczak, Waldemar
Suska, Anna
Dutka, Magdalena
Butrym, Aleksandra
Macauda, Angelica
Berndt, Sonja
Belachew, Alem A.
Gemignani, Federica
Hildebrandt, Michelle A.T.
Buda, Gabriele
Dumontet, Charles
Subocz, Edyta
Varkonyi, Judit
Reis, Rui Manuel
Abildgaard, Niels
Canzian, Federico
Sainz, Juan
Wątek, Marzena
Slager, Susan L.
Spinelli, John
Haastrup, Eva Kannik
Hofmann, Jonathan N.
Opis:: Gene expression profiling can be used for predicting survival in multiple myeloma (MM) and identifying patients who will benefit from particular types of therapy. Some germline single nucleotide polymorphisms (SNPs) act as expression quantitative trait loci (eQTLs) showing strong associations with gene expression levels. We performed an association study to test whether eQTLs of genes reported to be associated with prognosis of MM patients are directly associated with measures of adverse outcome. Using the genotype-tissue expression portal, we identified a total of 16 candidate genes with at least one eQTL SNP associated with their expression with P < $10^{-7}$ either in EBV-transformed B-lymphocytes or whole blood. We genotyped the resulting 22 SNPs in 1327 MM cases from the International Multiple Myeloma rESEarch (IMMEnSE) consortium and examined their association with overall survival (OS) and progression-free survival (PFS), adjusting for age, sex, country of origin and disease stage. Three polymorphisms in two genes (TBRG4-rs1992292, TBRG4- rs2287535 and ENTPD1-rs2153913) showed associations with OS at P < .05, with the former two also associated with PFS. The associations of two polymorphisms in TBRG4 with OS were replicated in 1277 MM cases from the International Lymphoma Epidemiology (InterLymph) Consortium. A meta-analysis of the data from IMMEnSE and InterLymph (2579 cases) showed that TBRG4-rs1992292 is associated with OS (hazard ratio = 1.14, 95% confidence interval 1.04-1.26, P = .007). In conclusion, we found biologically a plausible association between a SNP in TBRG4 and OS of MM patients.
Dostawca treści:: Repozytorium Uniwersytetu Jagiellońskiego