- Tytuł:
- The ChoCO-W prospective observational global study : Does COVID-19 increase gangrenous cholecystitis?
- Autorzy:
-
Lasithiotakis, Konstantinos
Kolla, Chrysoula-Christina
Bayhan, Zulfu
Sotiropoulou, Maria
Verras, Georgios Ioannis
Fabri, Nicolo
Lopez-Ruiz, Jose Antonio
Liman, Rumeysa Kevser
Massani, Marco
Azizan, Nornazirah
Capelli, Patrizio
Dogjani, Agron
Bouliaris, Konstantinos
Veroux, Massimiliano
Ibrahim, Mohamed
Abu-Zidan, Fikri M.
Occhionorelli, Savino
Andreuccetti, Jacopo
Ercolani, Giorgio
Atanasov, Boyko
Biffl, Walter L.
Lacavalla, Domenico
Nardello, Oreste
Agostinelli, Laura
Kwiatkowski, Andrzej
Colak, Elif
Palmieri Hernandez, Adriana Maria
Major, Piotr
Cappellacci, Federico
Uriguen-Etxeberria, Ana
Manatakis, Dimitrios K.
Palini, Gian Marco
Lupi, Davide
Gupta, Sanjay
Loutzidou, Lydia
Spolini, Alessandro
Litvin, Andrey
Capuzzolo, Sabino
Mendoza-Moreno, Fernando
Muzio, Elena
Olmi, Stefano
Khokha, Vladimir
Casoni Pattacini, Gianmaria
Tedesco, Silvia
Dumitrescu, Theodor Viorel
Roscio, Francesco
Abato, Emmanuele
Sartelli, Massimo
Triantafyllou, Tania
Hernandez Amín, Luz Adriana
Strzałka, Marcin
Massalou, Damien
Medas, Fabio
Andreotti, Dario
Miller, Kelsey
Aref, Hager
Maltinti, Gherardo
Podda, Mauro
Ietto, Giuseppe
Callari, Cosimo
Tvaladze, Ana
Al Bahri, Shadi
Abdullaev, Abakar
Campanile, Fabio Cesare
Ciorbagiu, Mihai Calin
Di Saverio, Salomone
Bayrak, Mehmet
Trigiante, Giuseppe
Gambarini, Fabrizio
Slavchev, Mihail
Azman, Azlanudin
Grassia, Sebastiano
Sellappan, Harivinthan
Palmieri Luna, Alfonso
Bonavina, Luigi
Negoi, Ionut
de Angelis, Nicola
Piccolo, Gaetano
Rossi, Stefano
Carcano, Giulio
Acheimastos, Vasileios
Agnoletti, Vanni
Matias-Garcia, Belen
Nikolopoulos, Ioannis
Zanus, Giacomo
Gonullu, Emre
Zulkifli, Anis Suraya M.
Delibegovic, Samir
Kojima, Mitsuaki
Quiroga-Valcarcel, Ana
Dalessio, Rossella
de Luca, Maurizio
Kumaz, Eray
Trinh, Anna
Bottari, Andrea
Meric, Serhat
Theodorou, Dimitrios
Kapiris, Stylianos
Akbar, Ali
Aliakbarian, Mohsen
Schizas, Dimitrios
Machain Vega, Gustavo
Canu, Gian Luigi
Moric, Trpimir
Ruggieri, Annamaria
Pisanu, Adolfo
Ozkan, Zeynep
Bagolini, Francesco
Norrey, Marcus
Tosi, Lorenzo
Vederaki, Styliani-Aikaterini
Xin Yi, Rebecca Choy
Aktimur, Yunus Emre
Asghar, Mohammad Sohail
Dorovinis, Panagiotis
Restini, Enrico
Armellino, Mariano Fortunato
Jung, Sung Won
Franchi, Caterina
Delis, Spiros G.
Moore, Ernest E.
de Lima Bertu, Jackson Vinicius
Licari, Leo
Bianco, Francesco
Vagios, Ilias
Abdel-Elsalam, Sherief
Lepiane, Pasquale
Moug, Susan J.
de Sa, Tiago Correia
Abdel-Elsalam, Wafaa
Ojeda, Leonardo
Munoz-Cruzado, Virginia Duran
Phooi Khei, Victoria Tan
Syllaios, Athanasios
Casati, Massimiliano
Volpicelli, Alessio
Vecchioni, Ilaria
Bains, Lovenish
Staderini, Fabio
Martines, Gennaro
Iftoda, Oksana
Gachabayov, Mahir
Nakamoto, Raira
Gabellini, Linda
Othman, Muhammad Asyraf
Bonaldi, Marta
Gumbs, Andrew A.
Dacapito, Fabrizio
Hedi Ghalloussi, Mohamed
Bonilauri, Stefano
Sidiropoulos, Theodoros A.
Galleano, Raffaele
Froiio, Caterina
Campagnacci, Roberto
Demirbas, Iskender Eren
Gurung, Rekha
Yalkin, Omer
Aparicio-Sanchez, Daniel
Pecchini, Francesca
Plehutsa, Oleksandr
Picardi, Biagio
Bondurri, Andrea
Vita, Domenico
Ioannidis, Orestis
Sartori, Alberto
Hamid, Hytham K.S.
Vacante, Marco
Pintar, Tadeja
Pujante, Antonio
Sin, Boo Han
Fransvea, Pietro
Damaskos, Dimitrios
Taddei, Antonio
Petronio, Barbara
Rahim, Razrim
Cavallaro, Andrea
Tasis, Nikolaos
Symeonidis, Savvas
Elbahnasawy, Mohamed
Michalopoulos, Nikolaos V.
Anastasi, Alessandro
Pesce, Antonio
Garulli, Gianluca
Baraket, Oussama
Misiakos, Evangelos P.
Costanzi, Andrea
Isik, Arda
Fortuna, Laura
Livadoti, Giada
Fleres, Francesco
Gomes, Felipe Couto
Gureh, Monika
Toma, Elena Adelina
Gelmini, Roberta
Pantalone, Desire
Veneroni, Simone
Balla, Andrea
Argenio, Giulio
Kirkpatrick, Andrew
Demetrashvili, Zaza
Dios Barbeito, Sandra
Sarnari, Jlenia
Ammerata, Giorgio
Deserra, Antonello
Curro, Giuseppe
Romero-Vargas, Estela
Chouillard, Elie
Conti, Luigi
Hirano, Elcio Shiyoiti
Pararas, Nikolaos
Serra, Francesco
Lekiashvili, Nika
Ansaloni, Luca
Romic, Ivan
Sydorchuk, Larysa
Shabana, Amanda
Rahman, Karim Abdul
Altintoprak, Fatih
Polat, Suleyman
Riva, Carlo
Poillucci, Gaetano
Das, Koray
Knut, Ruslan
Zanghi, Antonio
Jusoh, Asri Che
Catena, Fausto
Jedamzik, Julia
Rispoli, Michele
Kurtenkov, Mikhail
Cattaneo, Gaetano Maria
Kim, Jae Il
Nita, Gabriela
Doria, Emanuele
Gil-Olarte, Angeles
Maffioli, Anna
Gourgiotis, Stavros
Nagorni, Eleni-Aikaterini
Uzunoglu, Mustafa Yener
Ferrara, Francesco
Sani, Mohamad Ikhwan
Dai, Nick
Giordano, Alessio
Clarizia, Guglielmo
Cianchi, Fabio
Solaini, Leonardo
Giraudo, Giorgio
Chrysos, Emmanuel
Visconti, Diego
Czyżykowski, Łukasz
Dalili, Amin
Cappellani, Alessandro
Piccoli, Micaela
Gioco, Rossella
Rocha, Monica
Ammendola, Michele
Akin, Emrah
Grossi, Ugo
Pereira Fraga, Gustavo
Pikoulis, Emmanouil
Natkaniec, Michał
Landaluce-Olavarria, Aitor
Marinis, Athanasios
Atici, Semra Demirli
Zuhdi, Zamri
Tuncer, Gizem Kilinc
Seker, Ahmet
Altintas, Yasemin
Romano, Roberto
Kader, Saleh Abdel
Balogh, Zsolt J.
Rodriguez Gonzalez, Agustin
Azamat, Ibrahim
Zanzi, Federico
Estraviz-Mateos, Begona
Keramida, Myrto D.
Malerba, Michele
Biondi, Antonio
Shoko, Tomohisa
Borghi, Felice
Koylu, Zehra Alan
Kenig, Jakub
Capoglu, Recayi
Laface, Letizia
Koukoulis, George
Walędziak, Maciej
Dzulkarnaen, Zakaria Andee
Kluger, Yoram
Coccolini, Federico
Gendrikson, George
Felsenreich, Daniel M.
Cappato, Stefano
Santarelli, Mauro
Kaya, Tayfun
Guariniello, Anna
Matyja, Maciej
Lucchi, Andrea
Cillara, Nicola
Zainudin, Syaza
Anania, Gabriele
Cannavera, Alessandro
del Monte, Simone Rossi
Guagni, Tommaso
Papadoliopoulou, Maria
Iflazoglu, Nidal
Bombardini, Cristina
Machairas, Nikolaos
Negro, Giulia
Sawyer, Robert G.
Feo, Carlo Vittorio
Griggio, Giulia
Gomes, Carlos Augusto
Brisinda, Giuseppe
Ozer, Nazmi
Sydorchuk, Andrii
Mesina, Cristian
Papaconstantinou, Dimitrios
Canonico, Giuseppe
Omarov, Nail
Lostoridis, Eftychios
de Simone, Belinda
Bernardi, Daniele
Valenti, Maria Rosaria
Augustin, Goran
Cardinali, Luca
Afzal, Ameer
Ayed, Karim
Bala, Miklosh
Monteleone, Michela
Salobir, Jure
Patias, Parmenion
Pignata, Giusto
Martinotti, Mario
Sebastiani, Elisa
Piatto, Giacomo
Maurizi, Angela
Skorus, Urszula
Saeidi, Sara
Razat, Sulce
Yigit, Direnc
Rossi, Elena Giulia
Nardi, Matteo
Kedar, Asaf
Bisetto, Giovanni
Enciu, Octavian
Sasia, Diego
Martino, Costanza
Costanzo, Federico
Babiker, Ahmed
Guerci, Claudio
Tutino, Roberta
Mulita, Francesk
Ghoneim, Basma
Di Vita, Maria Domenica Pia
Vailas, Michail
Uymaz, Derya Salim
Andolfi, Enrico
Shin, Yong Chan
Altinel, Yuksel
Viola, Simona
Agresta, Ferdinando
Sydorchuk, Ruslan
Mousa, Hussam
Saramuzzo, Rosa
Hayati, Firdaus
Uccelli, Matteo
Filippo, Rosalinda
Kesetovic, Amar
Mantoglu, Baris
Ntokos, Georgios
Cianci, Pasquale
Kara, Yasin
Nikolo, Taxiarchis Konstantinos
Chuklin, Serhii
Clerici, Federico
Travaglini, Grazia
Agostini, Carlotta - Opis:
- Background: The incidence of the highly morbid and potentially lethal gangrenous cholecystitis was reportedly increased during the COVID-19 pandemic. The aim of the ChoCO-W study was to compare the clinical findings and outcomes of acute cholecystitis in patients who had COVID-19 disease with those who did not. Methods: Data were prospectively collected over 6 months (October 1, 2020, to April 30, 2021) with 1-month follow-up. In October 2020, Delta variant of SARS CoV-2 was isolated for the first time. Demographic and clinical data were analyzed and reported according to the STROBE guidelines. Baseline characteristics and clinical outcomes of patients who had COVID-19 were compared with those who did not. Results: A total of 2893 patients, from 42 countries, 218 centers, involved, with a median age of 61.3 (SD: 17.39) years were prospectively enrolled in this study; 1481 (51%) patients were males. One hundred and eighty (6.9%) patients were COVID-19 positive, while 2412 (93.1%) were negative. Concomitant preexisting diseases including cardiovascular diseases (p < 0.0001), diabetes (p < 0.0001), and severe chronic obstructive airway disease (p = 0.005) were significantly more frequent in the COVID-19 group. Markers of sepsis severity including ARDS (p < 0.0001), PIPAS score (p < 0.0001), WSES sepsis score (p < 0.0001), qSOFA (p < 0.0001), and Tokyo classification of severity of acute cholecystitis (p < 0.0001) were significantly higher in the COVID-19 group. The COVID-19 group had significantly higher postoperative complications (32.2% compared with 11.7%, p < 0.0001), longer mean hospital stay (13.21 compared with 6.51 days, p < 0.0001), and mortality rate (13.4% compared with 1.7%, p < 0.0001). The incidence of gangrenous cholecystitis was doubled in the COVID-19 group (40.7% compared with 22.3%). The mean wall thickness of the gallbladder was significantly higher in the COVID-19 group [6.32 (SD: 2.44) mm compared with 5.4 (SD: 3.45) mm; p < 0.0001]. Conclusions: The incidence of gangrenous cholecystitis is higher in COVID patients compared with non-COVID patients admitted to the emergency department with acute cholecystitis. Gangrenous cholecystitis in COVID patients is associated with high-grade Clavien-Dindo postoperative complications, longer hospital stay and higher mortality rate. The open cholecystectomy rate is higher in COVID compared with non -COVID patients. It is recommended to delay the surgical treatment in COVID patients, when it is possible, to decrease morbidity and mortality rates. COVID-19 infection and gangrenous cholecystistis are not absolute contraindications to perform laparoscopic cholecystectomy, in a case by case evaluation, in expert hands.
- Dostawca treści:
- Repozytorium Uniwersytetu Jagiellońskiego
Artykuł