- Tytuł:
- The SEQC2 epigenomics quality control (EpiQC) study : comprehensive characterization of epigenetic methods, reproducibility, and quantification
- Autorzy:
-
Lundmark, Anders
Padmanabhan, Karthik Ramaswamy
Muszyńska, Agata
Deng, Youping
Langhorst, Bradley W.
Cavalcante, Raymond
Gong, Ting
Rosas, Rocio
Scherer, Andreas
Davis, Justin Wade
Ponnaluri, V. K. Chaithanya
Bruinsma, Stephen
Mozsary, Christopher
Suzuki, Masako
Li, Jing
Megherbi, Dalila B.
Łabaj, Paweł
Lalancette, Claudia
Yang, Xiaopeng
Guo, Shang
Liao, Will
Golda, Gosia
Alonso, Alicia
Nasu, Masaki
Sheridan, Caroline
Wos, Frank
Xiao, Wenming
Axelsson, Tomas
Wang, Charles
Yang, Zhaowei
Melnick, Ari
Ibanez de Caceres, Inmaculada
Ishii, Jennifer
Liljedahl, Ulrika
Rodriguez-Antolin, Carlos
Tong, Weida
Franke, Vedran
Campbell, Matthew A.
Hong, Huixiao
Foox, Jonathan
Chen, Zhong
Ning, Baitang
Lacey, Michelle
Butler, Daniel
Lent, Samantha
Raine, Amanda
Nordlund, Jessica
Blume, Alexander
Akalin, Altuna
Mason, Christopher E.
Williams, Louise
Menor, Mark
Wang, Yunliang
Wang, Hongwei
Gurvitch, Justin
Xu, Joshua
Greally, John M. - Opis:
- Cytosine modifications in DNA such as 5-methylcytosine (5mC) underlie a broad range of developmental processes, maintain cellular lineage specification, and can define or stratify types of cancer and other diseases. However, the wide variety of approaches available to interrogate these modifications has created a need for harmonized materials, methods, and rigorous benchmarking to improve genome-wide methylome sequencing applications in clinical and basic research. Here, we present a multi-platform assessment and cross-validated resource for epigenetics research from the FDA’s Epigenomics Quality Control Group.
- Dostawca treści:
- Repozytorium Uniwersytetu Jagiellońskiego
Artykuł