Autor: Cecha, Patrycja - Prolib Integro

Skocz do pozycji: 1.

Tytuł:: Assessment of application of the new 2019 European Society of Cardiology/European Atherosclerosis Society Guidelines for the Management of Dyslipidaemias in daily clinical practice — one center study
Autorzy:: Cecha, Patrycja
Chromik, Anna
Piotrowska, Ilona
Zabojszcz, Michał
Dolecka-Ślusarczyk, Magdalena
Siudak, Zbigniew
Tematy:: cardiovascular risk
ESC/EAS guidelines
lipid-lowering therapy
PCSK9 inhibitors
statins; Pokaż więcej
Wydawca:: Polska Akademia Nauk. Czasopisma i Monografie PAN
Powiązania:: https://bibliotekanauki.pl/articles/56985284.pdf Link otwiera się w nowym oknie
Opis:: Background: Cardiovascular diseases are the first cause of death globally. Hypercholesterolemia is the most important factor responsible for atherosclerotic plaque formation and increasing cardiovascular risk. Reduction of LDL-C level is the most relevant goal for reduction of cardiovascular risk. Aims: Real life adherence to guidelines concerning statin therapy in one center study population. Methods: We analyzed data collected in the Department of Internal Diseases from September 2019 to February 2020, obtained from 238 patients hospitalized in this time period. We assessed application of the new 2019 ESC/EAS Guidelines for the Management of Dyslipidaemias in daily clinical practice and compared effectiveness of LLT according to 2016 and 2019 guidelines. Results: Only 1 in 5 patients with dyslipideamia achieve the 2019 ESC/EAS guideline-recommended levels of LDL-C with relation to their TCVR. We noticed that 20 of patients who did not achieve proper 2019 LDL level, meet the therapy targets established in year 2016. We observed that higher patient TCVR resulted in better compliance with guidelines and ordination of proper LLT. Most patients were on monotherapy with statins. Conclusions: It could be beneficial to start treatment with double or even triple therapy especially in group with the highest LDL-C levels.
Dostawca treści:: Biblioteka Nauki

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Tytuł:: Predictors and periprocedural outcomes of access crossover during primary percutaneous coronary interventions - a contemporary report from Polish ORPKI registry
Autorzy:: Kurzawski, Jacek
Piątek, Karolina
Cecha, Patrycja
Bartuś, Stanisław
Malinowski, Krzysztof
Siudak, Zbigniew
Sadowski, Marcin
Piątek, Łukasz
Opis:: Background: The radial artery became preferable access for percutaneous coronary interventions (PCI). The latest European Society of Cardiology guidelines strongly recommended transradial access in patients with ST-segment elevation myocardial infarction (STEMI). Though, in a significant portion of the coronary artery, invasive procedure crossover to femoral is necessary. Aims: This study aimed to determine the ratio, risk factors, and periprocedural outcomes of crossover from radial to femoral access during PCI in a contemporary STEMI registry. Methods: Based on data from the Polish registry ORPKI, we analyzed 90245 patients with a diagnosis of STEMI that were intended to be treated invasively via transradial access between 2014 and 2019. Results: In 1484 (1.6 %) individuals, a switch to femoral access was necessary during the procedure. The most important independent predictors of vascular crossover were female sex, previous coronary artery bypass graft, class 3 and 4 of the Killip scale, left main disease, as well as any complications during coronary angiography. In that cohort, the risk of bleeding at the puncture site was over 20-fold higher. Major disparities in periprocedural outcomes (death during procedure, cardiac arrest during PCI, Thrombolysis In Myocardial Infarction (TIMI) after PCI, and no-reflow) between these groups resulted from disparities in initial characteristics, and they were not associated with crossover itself. Conclusions: Even though the risk of crossover to femoral is currently low, it appears to be indispensable to sustain operators’ experience both in radial and femoral approaches to achieve the best outcomes in these patients.
Dostawca treści:: Repozytorium Uniwersytetu Jagiellońskiego

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