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Wyszukujesz frazę "Frank, Alexander" wg kryterium: Autor


Tytuł:
Smart operating room and surgery driven by artificial intelligence
Autorzy:
Frank, Alexander
Karcz, W. Konrad
Tematy:
sztuczna inteligencja
zarządzanie szpitalem
zarządzanie oddziałem chirurgicznym
sala operacyjna
artificial intelligence
hospital management
management of the surgical department
operating room
Pokaż więcej
Wydawca:
Międzynarodowe Stowarzyszenie na rzecz Robotyki Medycznej
Powiązania:
https://bibliotekanauki.pl/articles/2063771.pdf  Link otwiera się w nowym oknie
Opis:
From a surgical point of view, artificial intelligence (AI) does seem to be the holy grail of future medicine. Today data driven medicine influence also handwork - done with knifes, scissors, needles and sutures. Should a surgeon learn something about AI and data science? Big data, machine learning, NLP, video analysis and robotics will be a big part of modern surgery. Today’s operating robots like the Davinci already works with video analysis and machine learning. How AI will influence the OR of the future will be shown in this story. Please meet Dr. Smith. The surged of the future!
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Location-optimized aerodynamic rotor design studies and development of small wind turbines
Autorzy:
Lehser-Pfeffermann, Daniel
Hamman, Alexander
Rückert, Frank Ulrich
Tematy:
small wind turbine
fluid
energy machines
vertical axis wind turbine
additive manufacturing
fibre-reinforced composites
computational fluid dynamics
large eddy simulation
turbulence
simulation
Pokaż więcej
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Powiązania:
https://bibliotekanauki.pl/articles/2091356.pdf  Link otwiera się w nowym oknie
Opis:
Local wind conditions can vary strongly depending on the landmark and vegetation, as well as on the skyline of the buildings in an urban surrounding. Weather, season and time of day influence the yield of electric power. In order to promote the use of small wind turbines as an alternative to photovoltaic power generation, design optimization for location-optimized small wind turbines was carried out. In this work, we want to concentrate on vertical axis wind turbines. Experimental studies, as well as numerical simulations, have been conducted. On the one hand, bionically optimized core structures will be integrated and implemented in the hybrid material of the turbine blades. Several optimization attempts have been examined for single blades. Detailed simulative investigations with large eddy simulations improve the aerodynamic behaviour of the new rotor design. Finally, based on the results of the studies and investigations, a new rotor will be manufactured and tested experimentally in the wind tunnel. A comparison with the reference system from the first part of the paper shows the improvements and effectiveness of the measures and processes investigated.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Magnetic resonance-guided direct shoulder arthrography for the detection of superior labrum anterior-posterior lesions using an open 1.0-T MRI scanner
Autorzy:
Fischbach, Frank
Lohmann, Christoph
Berth, Alexander
Stendel, Linda
Pozniak, Agnieszka
Pech, Maciej
Opis:
Purpose: Direct magnetic resonance arthrography (MRA) offers increased diagnostic accuracy compared to conventional magnetic resonance imaging (MRI) in the detection of superior labrum anterior-posterior (SLAP) lesions. The aim of the present study was to present the technique of magnetic resonance-guided direct shoulder arthrography (MDSA), to evaluate the diagnostic value of this novel MRA procedure to detect SLAP lesions in comparison to the currently practiced MRI, and to correlate the radiological findings to the respective arthroscopic findings. Material and methods: Fifty-six patients with clinical signs of a SLAP lesion underwent both MRI examination and MDSA prior to arthroscopic surgery. The MRI of both interventions were compared with the arthroscopic findings. Statistical analysis was performed using the McNemar test. Results: Sensitivity, specificity, and accuracy for detecting SLAP lesions were 23%, 88%, and 54% on MRI and 80%, 81%, and 80% on MDSA, respectively. Sensitivity (p < 0.001) and accuracy (p = 0.001) in detection of SLAP lesions were significantly higher by MDSA whereas accuracy showed no significant differences (p = 0.625). Conclusions: The MDSA can be performed in an open 1.0-T MRI scanner with a high level of technical success and a reasonable methodical effort. The modification of MRA provides the requirements as a practicable routine shoulder magnetic resonance examination including arthrography to detect SLAP lesions. The diagnostic value is significantly better than MRI examinations without included arthrography, which currently predominates the clinical practice to investigate shoulder pathology.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
Tytuł:
Inhibition of SARS-CoV-2 infection by Porphyromonas gingivalis and the oral microbiome
Autorzy:
Antonson, Sibel A.
Godoy, Cristina
Pastore, Maria R.
Shindo, Satoru
Bontempo, Alexander
Kawai, Toshihisa
Potempa, Jan
Cayabyab, Mark J.
Chirino, Alexandra
Nichols, Frank C.
Davey, Mary Ellen
Heidari, Alireza
Lugo, Alexandra
Madonia, Riccardo
Opis:
The COVID-19 pandemic persists despite the availability of vaccines, and it is, therefore, crucial to develop new therapeutic and preventive approaches. In this study, we investigated the potential role of oral microbiome in SARS-CoV-2 infection. Using an in vitro SARS-CoV-2 pseudovirus infection assay, we found a potent inhibitory effect exerted by Porphyromonas gingivalis on SARS-CoV-2 infection mediated by known P. gingivalis compounds such as phosphoglycerol dihydroceramide (PGDHC) and gingipains as well as by unknown bacterial factors. We found that the gingipain-mediated inhibition of infection is likely due to cytotoxicity, whereas PGDHC inhibited virus infection by an unknown mechanism. Unidentified factors present in P. gingivalis supernatant inhibited SARS-CoV-2 likely via the fusion step of the virus life cycle. We addressed the role of other oral bacteria and found certain periodontal pathogens capable of inhibiting SARS-CoV-2 pseudovirus infection by inducing cytotoxicity on target cells. In the human oral cavity, we observed that the modulatory activity of oral microbial communities varied among individuals, in that some saliva-based cultures were capable of inhibiting while others were enhancing infection. These findings contribute to our understanding of the complex relationship between the oral microbiome and viral infections, offering potential avenues for innovative therapeutic strategies in combating COVID-19.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł

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