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Wyszukujesz frazę "Gronek, Piotr" wg kryterium: Autor


Wyświetlanie 1-10 z 10
Tytuł:
Genetic variants of uncoupling proteins-2 and -3 in relation to maximal oxygen uptake in different sports
Autorzy:
Holdys, Joanna
Gronek, Piotr
Kryściak, Jakub
Stanisławski, Daniel
Tematy:
UCP2
athletic performance
genetic polymorphism
UCP3
energy efficiency
Pokaż więcej
Wydawca:
Polskie Towarzystwo Biochemiczne
Powiązania:
https://bibliotekanauki.pl/articles/1039610.pdf  Link otwiera się w nowym oknie
Opis:
Uncoupling proteins 2 and 3 (UCP2 and UCP3) as mitochondrial electron transporters are involved in regulation of ATP production and energy dissipation as heat. Energy efficiency plays an important role in physical performance, especially in aerobic fitness. The aim of this study was to examine the association between maximal oxygen uptake and genetic variants of the UCP2 and UCP3 genes. The studies were carried out in a group of 154 men and 85 women, professional athletes representing various sports and fitness levels and students of the University of Physical Education in Poznań. Physiological and molecular procedures were used, i.e. direct measurement of maximum oxygen uptake (VO2max) and analysis of an insertion/deletion (I/D) polymorphism in the 3'untranslated region of exon 8 of the UCP2 gene and a C>T substitution in exon 5 (Y210Y) of the UCP3 gene. No statistically significant associations were found, only certain trends. Insertion allele (I) of the I/D UCP2 and the T allele of the UCP3 gene were favourable in obtaining higher VO2max level and might be considered as endurance-related alleles.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Maximal oxygen uptake is associated with allele -202 A of insulin-like growth factor binding protein-3 (IGFBP3) promoter polymorphism and (CA)n tandem repeats of insulin-like growth factor IGF1 in Caucasians from Poland
Autorzy:
Gronek, Piotr
Holdys, Joanna
Kryściak, Jakub
Wieliński, Dariusz
Słomski, Ryszard
Tematy:
IGF1
IGFBP3
athletic performance
genetic polymorphism
energy efficiency
Pokaż więcej
Wydawca:
Polskie Towarzystwo Biochemiczne
Powiązania:
https://bibliotekanauki.pl/articles/1039282.pdf  Link otwiera się w nowym oknie
Opis:
Physical fitness is a trait determined by multiple genes, and its genetic basis is modified by numerous environmental factors. The present study examines the effects of the (CA)n tandem repeats polymorphism in IGFI gene and SNP Alw21I restriction site -202 A>C polymorphism in IGF1BP3 on VO2max - a physiological index of aerobic capacity of high heritability. The study sample consisted of 239 (154 male and 85 female) students of the University School of Physical Education in Poznań and athletes practicing various sports, including members of the Polish national team. An association was found between -202 A/C polymorphism of IGFBP3 gene with VO2max in men. Higher VO2max values were attained by men with CC genotype, especially male athletes practicing endurance sports and sports featuring energy metabolism of aerobic/anaerobic character. A statistically significant influence of allele 188 and genotype 188/188 of tandem repeats (CA)n polymorphism of IGF1 gene on VO2max was found in women. Also, lower values of maximal oxygen uptake were noted in individuals with allele 186 or genotype 186/186, and higher VO2max values in athletes with allele 194.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The relationship between CA repeat polymorphism of the IGF-1 gene and the structure of motor skills in young athletes
Autorzy:
Karpowicz, Krzysztof
Krych, Katarzyna
Karpowicz, Małgorzata
Nowak, Witold
Gronek, Piotr
Tematy:
genetic variations
motor skills
young athletes
Pokaż więcej
Wydawca:
Polskie Towarzystwo Biochemiczne
Powiązania:
https://bibliotekanauki.pl/articles/1038522.pdf  Link otwiera się w nowym oknie
Opis:
The map of candidate genes that can potentially affect physical fitness becomes larger every year, and they are associated with such aspects as respiratory and cardiovascular stability; body build and composition - especially muscle mass and strength; carbohydrate and lipid metabolism; response to training; and exercise intolerance.The aim of this study was to analyze the relationship between the CA repeat polymorphism of the P1 promoter of the IGF1 gene and the structure of motor skills in the two groups of Polish young athletes in 2007-2009. In this study, 350 young sportsmen representing different sports disciplines were examined (age = 15.5 ± 0.5 years), by genotyping the IGF1 gene and determining the structure of motor skills using the International Physical Fitness Test (IPFT) battery. The multiple stepwise regression was used to determine the impact of the investigated motor skills on the indicator of the overall physical fitness, measured by the total score of the International Physical Fitness Test (IPFT). The analysis showed some regularity related to the character of the IGF1 gene polymorphism. It can be concluded that the two groups of young boys athletes practicing various sports disciplines (kinds of physical exercise) displayed similar associations between CA repeat polymorphism of the P1 promoter of the IGF1 gene and the level of motor effects. Our results suggest that this polymorphism may be a genetic marker of the physical performance phenotype. We demonstrated that CA repeat polymorphism of the P1 promoter of the IGF1 gene was associated with strength predispositions in the homozygous and non-carriers groups. In the group who were heterozygous it was speed-strength aptitudes.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ekspresyjne konstrukcje genowe prawidłowych i zmutowanych genów
Expressive gene structures of proper and modified genes
Autorzy:
Gronek, Piotr
Jura, Jolanta
Nuc, Katarzyna
Jura, Jacek
Słomski, Ryszard
Juzwa, Wojciech
Słomska, Karolina
Lipiński, Daniel
Kala, Marta
Smorąg, Zdzisław
Pieńkowski, Marek
Pławski, Andrzej
Kalak, Robert
Szalata, Marlena
Wydawca:
Committee on Biotechnology PAS
Komitet Biotechnologii PAN
Institute of Bioorganic Chemistry PAS
Instytut Chemii Bioorganicznej PAN
Powiązania:
Biotechnologia, vol.60, 1 (2003)-.
Opis:
The genetic construct WAP6xHisHGH containing the gene encoding humangrowth hormone (hGH) and WAP promoter expressed in mammary gland of animals was prepared. The 5’ end of the gene was modified by the addition of sequence encoding six histidine residues and the sequence recognized bythrombin. In this way, the growth hormone can be easily purified by affinitychromatography and cleaved with thrombin to an active form. In the next step,the genetic construct was introduced by microinjection into male pronuclei offertilized oocytes. Transgene was detected in male rabbit of FO generation(number 61). Twelve offspring of founder rabbit of generation FI indicatedtransgene sequences. The presence of growth hormone was revealed in thesamples of milk accumulated during the lactation of females of FI generation.The genetic constructs containing chain 1 and chain 2 of Feld I, and the majorallergen produced by cat (Fedlis domesticus) were prepared.
Dostawca treści:
RCIN - Repozytorium Cyfrowe Instytutów Naukowych
Książka
Tytuł:
Cerkiew grecko-katolicka pw. Opieki Przenajświetszej Bogurodzicy w Budyninie
The Church of the Protection of the Most Holy Mother of God in Budynin
Autorzy:
Pilipowicz, Denys
Sygowski, Paweł
Mazur, Wiktoria
Kich-Masłej, Olga
Nowak, Alicja
Gronek, Agnieszka
Warzecha, Anna
Wojnarowski, Marek
Babych, Anna
Warmińska-Mazurek, Katarzyna
Skorniewski, Mariusz
Współwytwórcy:
Krawiec, Piotr
Opis:
The Church of the Protection of the Most Holy Mother of God in Budynin was built in 1887. It is a wooden structure, erected on a tripartite plan, using log construction, partially clad with boards, and topped with three domes. Inside, there is a Neo-Baroque polychrome decoration from 1892, both ornamental and figural. In the same year, the iconostasis was created: the icons were purchased in Munich, and the wooden frame was crafted by the sculptor Rinke from Sokal. In the sanctuary, there is a monumental altarpiece featuring the painting of the Immaculate Conception of the Blessed Virgin Mary. In the vestibule, there are two icon cases (kiots): on the right, an icon of Christ, and on the left, the Virgin Mary with the Child. The icons are older and have been repainted; the fragments of icon cases were assembled from the old iconostasis. On the walls, there are processional crosses, small paintings — some in the oleograph technique — and 19th-century feretrons painted on metal, displayed in glass cases. Next to the church stands a wooden bell tower built in 1866. A few hundred meters from the church, there is an old cemetery with stone tombstones.
Cerkiew pw. Pokrow Przenajświętszej Bogurodzicy w Budyninie wybudowano w roku 1887. Drewniana, wzniesiona na planie trójdzielnym, w konstrukcji zrębowej, częściowo oszalowana, zwieńczona trzema kopułami. Wewnątrz polichromia neobarokowa z roku 1892: ornamentalna i figuralna. W tym samym roku powstał ikonostas: ikony kupiono w Monachium, drewaniną ramę wykonał rzeźbiarz Rinke z Sokala. W sanktuarium monumentalna nastawa ołtarzowa z obrazem Niepokalanego Poczęcia Najświętszej Panny Marii. W przedsionku dwa kioty z ikonami Chrystusa na prawo i Matki Boskiej z Dzieciątkiem na lewo. Ikony starsze, przemalowane, kioty zbite z dawnego ikonostasu. Na ścianach porozwieszane krzyże procesjonalne, drobne obrazy, także w technice oleodruku, w gablotach XIX-wieczne feretrony malowane na blasze. Obok cerkwi drewniana dzwonnica wzniesiona w 1866 roku. Kilkaset metrów od cerkwi stary cmentarz z kamiennymi nagrobkami.
Церква Покрови Пресвятої Богородиці в Будининi була збудована у 1887 році. Дерев’яна, зведена у триподільному плані, у зрубній конструкції, частково обшита дошками, завершена трьома куполами. Усередині — необарокова поліхромія з 1892 року: орнаментальна і фігуральна. Тоді також був створений іконостас: ікони придбано у Мюнхені, дерев’яну раму виготовив різьбяр Рінке із Сокаля. У святилищі — монументальний вівтар з образом Непорочного Зачаття Пресвятої Діви Марії. У притворі — два кіоти з іконами: праворуч — Христа, ліворуч — Богородиці з Дитям. Ікони старі, перемальовані, фрагменти кіотів перенесені зі старого іконостасу. На стінах розвішані процесійні хрести, невеликі образи, зокрема й у техніці олеодруку, у вітринах — феретрони XIX століття, написані на блясі. Поруч із церквою дерев’яна дзвіниця, зведена у 1866 році. За кількасот метрів від церкви — старий цвинтар з кам’яними надгробками.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Książka
    Wyświetlanie 1-10 z 10

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