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Wyszukujesz frazę "Howard, George" wg kryterium: Autor


Tytuł:
Secondary stroke prevention in polish adults : results from the LIPIDOGRAM2015 study
Autorzy:
Tomasik, Tomasz
Charchar, Fadi J.
Howard, George
MacDonald, Thomas M.
Mastej, Miroslaw
Labuz-Roszak, Beata
Banach, Maciej
Lip, Gregory Y. H.
Windak, Adam
Catapano, Alberico
Tomaszewski, Maciej
Toth, Peter P.
Sattar, Naveed
Williams, Bryan
Mikhailidis, Dimitri P.
Penson, Peter
Skrzypek, Michal
Jozwiak, Jacek J.
Ray, Kausik K.
Opis:
Background: The purpose of the study was to evaluate secondary stroke prevention in Poland and its association with sociodemographic factors, place of residence, and concomitant cardiovascular risk factors. Material and methods: From all patients in LIPIDOGRAM2015 Study (n = 13,724), 268 subjects had a history of ischaemic stroke and were included. Results: 165 subjects (61.6%) used at least one preventive medication. Oral antiplatelet and anticoagulation agents were used by 116 (43.3%) and 70 (26.1%) patients, respectively. Only 157 (58.6%) participants used lipid-lowering drugs, and 205 (76.5%) were treated with antihypertensive drugs. Coronary heart disease (CHD) and dyslipidaemia were associated with antiplatelet treatment (p = 0.047 and p = 0.012, respectively). A history of atrial fibrillation, CHD, and previous myocardial infarction correlated with anticoagulant treatment (p = 0.001, p = 0.011, and p < 0.0001, respectively). Age, gender, time from stroke onset, place of residence, and level of education were not associated with antiplatelet or anticoagulant treatment. Only 31.7% of patients were engaged in regular physical activity, 62% used appropriate diet, and 13.6% were current smokers. Conclusions: In Poland drugs and lifestyle modification for secondary stroke prevention are not commonly adhered to. Educational programmes for physicians and patients should be developed to improve application of effective secondary prevention of stroke.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
Tytuł:
The differences in the prevalence of cardiovascular disease, its risk factors, and achievement of therapeutic goals among urban and rural primary care patients in Poland : results from the LIPIDOGRAM 2015 study
Autorzy:
Tomasik, Tomasz
Studziński, Krzysztof
Ray, Kausik K.
Williams, Bryan
Charchar, Fadi J.
Tomaszewski, Maciej
Lip, Gregory Y.H.
Penson, Peter E.
Catapano, Alberico
Sattar, Naveed
Mastej, Mirosław
Wójtowicz, Ewa
Banach, Maciej
Mikhailidis, Dimitri P.
Toth, Peter P.
MacDonald, Thomas M.
Windak, Adam
Jóźwiak, Jacek J.
Howard, George
Opis:
A nationwide cross-sectional study, LIPIDOGRAM2015, was carried out in Poland in the years 2015 and 2016. A total of 438 primary care physicians enrolled 13,724 adult patients that sought medical care in primary health care practices. The prevalence of hypertension, diabetes mellitus, dyslipidaemia, and CVD were similar in urban and rural areas (49.5 vs. 49.4%; 13.7 vs. 13.1%; 84.2 vs. 85.2%; 14.4 vs. 14.2%, respectively). The prevalence of obesity (32.3 vs. 37.5%, p < 0.01) and excessive waist circumference (77.5 vs. 80.7%, p < 0.01), as well as abdominal obesity (43.2 vs. 46.4%, p < 0.01), were higher in rural areas in both genders. Mean levels of LDL-C (128 vs. 130 mg/dL, p = 0.04) and non-HDL-C (147 vs. 148 mg/dL, p = 0.03) were slightly higher in rural populations. Altogether, 14.3% of patients with CVD from urban areas and 11.3% from rural areas reached LDL <70 mg/dL (p = 0.04). There were no important differences in the prevalence of hypertension, diabetes, dyslipidaemia, and CVD, or in mean levels of blood pressure, cholesterol fractions, glucose, and HbA1c between Polish urban and rural primary care patient populations. A high proportion of patients in cities and an even-higher proportion in rural areas did not reach the recommended targets for blood pressure, LDL-C, and HbA1c, indicating the need for novel CVD-prevention programs.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
Tytuł:
Analysis of the impact of sex and age on the variation in the prevalence of antinuclear autoantibodies in Polish population : a nationwide observational, cross-sectional study
Autorzy:
Mikhailidis, Dimitri P.
Catapano, Alberico
Mastej, Mirosław
Toth, Peter P.
Lip, Gregory Y.H.
Banach, Maciej
Krzemien, Paweł
Charchar, Fadi J.
Windak, Adam
Tomasik, Tomasz
Howard, George
Penson, Peter E.
MacDonald, Thomas M.
Sattar, Naveed
Tomaszewski, Maciej
Kasperczyk, Sławomir
Kasperczyk, Aleksandra
Ray, Kausik K.
Williams, Bryan
Jóźwiak, Jacek J.
Dobrakowski, Michał
Opis:
The detection of antinuclear autoantibody (ANA) is dependent on many factors and varies between the populations. The aim of the study was first to assess the prevalence of ANA in the Polish adult population depending on age, sex and the cutoff threshold used for the results obtained. Second, we estimated the occurrence of individual types of ANA-staining patterns. We tested 1731 patient samples using commercially available IIFA using two cutoff thresholds of 1:100 and 1:160. We found ANA in 260 participants (15.0%), but the percentage of positive results strongly depended on the cutoff level. For a cutoff threshold 1:100, the positive population was 19.5% and for the 1:160 cutoff threshold, it was 11.7%. The most prevalent ANA-staining pattern was AC-2 Dense Fine speckled (50%), followed by AC-21 Reticular/AMA (14.38%) ANA more common in women (72%); 64% of ANA-positive patients were over 50 years of age. ANA prevalence in the Polish population is at a level observed in other highly developed countries and is more prevalent in women and elderly individuals. To reduce the number of positive results released, we suggest that Polish laboratories should set 1:160 as the cutoff threshold.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
Tytuł:
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
Autorzy:
Psaty, Bruce M.
Longstreth Jr, W. T.
Chen, Wei-Min
Amouyel, Philippe
Schmidt, Reinhold
Lange, Leslie A.
Maguire, Jane
Cole, John W.
Ridker, Paul M.
Cotlarciuc, Ioana
Salomaa, Veikko
Bartz, Traci M.
Havulinna, Aki S.
den Hoed, Marcel
Chambers, John C.
Anderson, Christopher D.
Nalls, Michael A.
Kooperberg, Charles
Kleindorfer, Dawn O.
Ikram, M. Arfan
Markus, Hugh S.
Seshadri, Sudha
Thorsteinsdottir, Unnur
Gottesman, Rebecca F.
Ninomiya, Toshiharu
Mosley, Thomas H.
Malik, Rainer
Takeuchi, Fumihiko
Correa, Adolfo
Hata, Jun
Manichaikul, Ani
Carrera, Caty
Hassan, Ahamad
van Duijn, Cornelia M.
Trompet, Stella
Lubitz, Steven A.
Engelter, Stefan T.
Taylor, Kent D.
Tregouet, David A.
Duan, Qing
Kooner, Jaspal S.
Benavente, Oscar R.
Mitchell, Braxton D.
Smith, Nicholas L.
Okada, Yukinori
Kissela, Brett M.
Rexrode, Kathryn M.
Bis, Joshua C.
Grewal, Raji P.
Rundek, Tatjana
Chasman, Daniel I.
Holliday, Elizabeth G.
Jimenez-Conde, Jordi
Wareham, Nicholas J.
Tzourio, Christophe
Pulit, Sara L.
Mishra, Aniket
Wilson, James G.
Lemmens, Robin
Howson, Joanna M. M.
Christophersen, Ingrid E.
Kamatani, Yoichiro
Magnusson, Patrik K.
Rosand, Jonathan
DeStefano, Anita L.
Tatlisumak, Turgut
Jern, Christina
Kato, Norihiro
Carty, Cara L.
Danesh, John
de Bakker, Paul I. W.
Boncoraglio, Giorgio B.
McArdle, Patrick F.
Reiner, Alexander P.
Rutten-Jacobs, Loes
Tai, E. Shyong
Hopewell, Jemma C.
Kittner, Steven J.
Tanislav, Christian
Traylor, Matthew
Pare, Guillaume
Gustafsson, Stefan
Irvin, Marguerite R.
Lindgren, Arne G.
Launer, Lenore J.
Giese, Anne-Katrin
Haessler, Jeffrey
Strbian, Daniel
Sharma, Pankaj
Fernandez-Cadenas, Israel
Dichgans, Martin
Cruchaga, Carlos
Chauhan, Ganesh
Sacco, Ralph L.
Yusuf, Salim
Sale, Michele M.
Lee, Jin-Moo
Rannikmae, Kristiina
Gudnason, Vilmundur
Lin, Wei-Yu
Rice, Kenneth
Johnson, Andrew D.
Rothwell, Peter M.
Walters, Matthew
Ay, Hakan
Lewis, Cathryn M.
Leys, Didier
van der Laan, Sander W.
Sargurupremraj, Muralidharan
Schadt, Eric E.
Rolfs, Arndt
Słowik, Agnieszka
Debette, Stephanie
Hyacinth, Hyacinth I.
Heckbert, Susan R.
Thijs, Vincent N. S.
Sakaue, Saori
Almgren, Peter
Saleheen, Danish
Langenberg, Claudia
Hsu, Fang-Chi
Rich, Stephen S.
Sudlow, Cathie L.M.
Ruusalepp, Arno
Falcone, Guido J.
Jian, Xueqiu
Meschia, James F.
Pastinen, Tomi
Melander, Olle
Codoni, Veronica
Civelek, Mete
Harris, Tamara B.
Ellinor, Patrick T.
Wiggins, Kerri L.
Wassertheil-Smoller, Sylvia
Ingelsson, Erik
Schminke, Ulf
Roselli, Carolina
Langefeld, Carl D.
Sanghera, Dharambir K.
Brown Jr, Robert D.
Kanai, Masahiro
O'Donnell, Martin J.
van der Harst, Pim
Lorentzen, Erik
Rost, Natalia S.
Stefansson, Kari
Bjorkegren, Johan L. M.
Johnson, Julie A.
Bevan, Steve
Thorleifsson, Gudmar
Worrall, Bradford B.
Chong, Michael
Kubo, Michiaki
Tiedt, Steffen
Butterworth, Adam S.
Howard, George
Jukema, J. Wouter
Adams, Hieab H. H.
Rotter, Jerome I.
Keene, Keith L.
Koplev, Simon
Woo, Daniel
Yang, Qiong
Sapkota, Bishwa R.
He, Jiang
Fornage, Myriam
Ago, Tetsuro
Schmidt, Carsten O.
Gretarsdottir, Solveig
Elliott, Paul
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł

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