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Wyświetlanie 1-10 z 37
Tytuł:
Equipment exploitation in power to gas installation
Autorzy:
Kotowicz, Janusz
Jurczyk, Michał
Węcel, Daniel
Tematy:
zasilanie gazem
generator wodoru
magazyn energii
power to gas
hydrogen generator
energy storage
Pokaż więcej
Wydawca:
STE GROUP
Powiązania:
https://bibliotekanauki.pl/articles/27315938.pdf  Link otwiera się w nowym oknie
Opis:
The article presents idea of installation to energy storage in the form of hydrogen - Power to Gas (P2G). The results of laboratory tests carried out at the Silesian University of Technology in the Institute of Power Engineering and Turbomachinery (IMiUE), covering selected aspects of hydrogen generators most frequently used in these types of installations are presented. The influence of water conductivity and temperature during continuous operation of the electrolyzer at constant current value and in operation at variable current on the efficiency of the tested devices are shown. A hydrogen generator equipped with two AEM electrolyzers with a performance of 0.5 Nm3H2/h and a generator containing four PEM electrolyzers connected in series, with a maximum performance of 1.58 Ndm3/min were tested. The efficiency characteristics of the electrolysis process, efficiency of the electrolyzers and changes in the resistance values for both types of electrolyzers were presented. Calculations to estimate effect of temperature change on the efficiency characteristic of AEM electrolyzers were also made.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Differences in the cardiovascular hemodynamic response between the Valsalva and Reverse Valsalva Maneuvers in healthy subjects
Autorzy:
Boryczko, Andrzej
Furgała, Agata
Jurczyk, Michał
Augustyn, Karolina
Gil, Krzysztof
Tematy:
supraventricular tachycardia
Vagal maneuver
Reverse Valsalva
autonomic nervous system
Pokaż więcej
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Powiązania:
https://bibliotekanauki.pl/articles/57110652.pdf  Link otwiera się w nowym oknie
Opis:
Background: The Valsalva Maneuver (VM) is the first-line treatment for paroxysmal supra-ventricular tachycardia, but a recent, novel, and efficient tool to restore sinus rhythm has been described, i.e., the Reverse Valsalva (RV). This study aims to compare changes in cardiovascular hemodynamics and autonomic system activity (ANS) based on heart rate variability (HRV) analysis during both maneuvers. Methods: Fifteen healthy participants performed the VM and RV maneuvers three times in a sitting position for durations of 15 s and 10 s, respectively. Blood pressure (BP) and heart rate (HR) were continuously monitored before, during and after the tests. Autonomic system activity was evaluated using frequency-domain analysis of HRV. Results: The decrease in HR from baseline to the lowest values, expressed as a ratio, was similar during both maneuvers (0.81 during the RV vs. 0.79 during the VM, p = 0.27). However, the final lowest HR in response to the RV was higher than that in response to the VM, 70/min vs. 59/min (p <0.001). The activation of the autonomic nervous system during the most bradycardic phase of the RV (phase II) and VM (phase IV) showed that the total power of HRV was less prominent during the RV than during the VM (p <0.012), with similar levels of parasympathetic activation. Conclusions: Our results showed less HR slowdown during the RV than during the VM. The changes in HRV parameters during both procedures in particular phases of the RV and VM suggest that the autonomic nervous system is activated alternately, so these tests can be used complementarily in a clinical setting with different results.
Dostawca treści:
Biblioteka Nauki
Artykuł
Autorzy:
Jurczyk, Michał
Furgała, Agata
Gil, Krzysztof
Boryczko, Andrzej
Augustyn, Karolina
Opis:
Background: The Valsalva Maneuver (VM) is the first-line treatment for paroxysmal supra-ventricular tachycardia, but a recent, novel, and efficient tool to restore sinus rhythm has been described, i.e., the Reverse Valsalva (RV). This study aims to compare changes in cardiovascular hemodynamics and autonomic system activity (ANS) based on heart rate variability (HRV) analysis during both maneuvers. Methods: Fifteen healthy participants performed the VM and RV maneuvers three times in a sitting position for durations of 15 s and 10 s, respectively. Blood pressure (BP) and heart rate (HR) were continuously monitored before, during and after the tests. Autonomic system activity was evaluated using frequency-domain analysis of HRV. Results: The decrease in HR from baseline to the lowest values, expressed as a ratio, was similar during both maneuvers (0.81 during the RV vs. 0.79 during the VM, p = 0.27). However, the final lowest HR in response to the RV was higher than that in response to the VM, 70/min vs. 59/min (p <0.001). The activation of the autonomic nervous system during the most bradycardic phase of the RV (phase II) and VM (phase IV) showed that the total power of HRV was less prominent during the RV than during the VM (p <0.012), with similar levels of parasympathetic activation. Conclusions: Our results showed less HR slowdown during the RV than during the VM. The changes in HRV parameters during both procedures in particular phases of the RV and VM suggest that the auto-nomic nervous system is activated alternately, so these tests can be used complementarily in a clinical setting with different results.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
Tytuł:
Past strong experiences determine acute cardiovascular autonomic responses to acoustic stress
Autorzy:
Jurczyk, Michał
Boryczko, Andrzej
Furgała, Agata
Poniatowski, Adrian
Surdacki, Andrzej
Gil, Krzysztof
Tematy:
stress
students
autonomic system activity
heart rate variability
blood pressure variability
Pokaż więcej
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Powiązania:
https://bibliotekanauki.pl/articles/56896928.pdf  Link otwiera się w nowym oknie
Opis:
Background: Stress is a major risk factor for cardiovascular (CV) disease. We hypothesized that past strong experiences might modulate acute CV autonomic responses to an unexpected acoustic stimulus. Aim: The study’s aim was to compare acute CV autonomic responses to acoustic stress between students with and without a past strong experience associated with the acoustic stimulus. Materials and Methods: Twenty five healthy young volunteers — medical and non-medical students — were included in the study. CV hemodynamic parameters, heart rate (HR), and blood pressure (BP) variability were assessed for 10 min at rest and for 10 min after two different acoustic stimuli: a standard sound signal and a specific sound signal used during a practical anatomy exam (so-called “pins”). Results: Both sounds stimulated the autonomic nervous system. The “pins” signal caused a stronger increase in HR in medical students (69 ± 10 vs. 73 ± 13 bpm, p = 0.004) when compared to non-medical students (69 ± 6 vs. 70 ± 10, p = 0.695). Rises in diastolic BP, observed 15 seconds after sound stressors, were more pronounced after the “pins” sound than after the standard sound signal only in medical students (3.1% and 1.4% vs. 3% and 4.4%), which was also reflected by low-frequency diastolic BP variability (medical students: 6.2 ± 1.6 vs. 4.1 ± 0.8 ms2, p = 0.04; non-medical students: 6.0 ± 4.3 vs. 4.1 ± 2.6 ms2, p = 0.06). Conclusions: The “pins” sound, which medical students remembered from their anatomy practical exam, provoked greater sympathetic activity in the medical student group than in their non-medical peers. Thus, past strong experiences modulate CV autonomic responses to acute acoustic stress.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Past strong experiences determine acute cardiovascular autonomic responses to acoustic stress
Autorzy:
Poniatowski, Adrian
Gil, Krzysztof
Jurczyk, Michał
Furgała, Agata
Boryczko, Andrzej
Surdacki, Andrzej
Opis:
Background: Stress is a major risk factor for cardiovascular (CV) disease. We hypothesized that past strong experiences might modulate acute CV autonomic responses to an unexpected acoustic stimulus. A i m: The study’s aim was to compare acute CV autonomic responses to acoustic stress between students with and without a past strong experience associated with the acoustic stimulus. Materials and Methods: Twenty five healthy young volunteers - medical and non-medical students - were included in the study. CV hemodynamic parameters, heart rate (HR), and blood pressure (BP) variability were assessed for 10 min at rest and for 10 min after two different acoustic stimuli: a standard sound signal and a specific sound signal used during a practical anatomy exam (so-called "pins"). Results: Both sounds stimulated the autonomic nervous system. The "pins" signal caused a stronger increase in HR in medical students (69 ± 10 vs. 73 ± 13 bpm, p = 0.004) when compared to non-medical students (69 ± 6 vs. 70 ± 10, p = 0.695). Rises in diastolic BP, observed 15 seconds after sound stressors, were more pronounced after the "pins" sound than after the standard sound signal only in medical students (3.1% and 1.4% vs. 3% and 4.4%), which was also reflected by low-frequency diastolic BP variability (medical students: 6.2 ± 1.6 vs. 4.1 ± 0.8 ms2, p = 0.04; non-medical students: 6.0 ± 4.3 vs. 4.1 ± 2.6 ms2, p = 0.06). Conclusions: The "pins" sound, which medical students remembered from their anatomy practical exam, provoked greater sympathetic activity in the medical student group than in their non-medical peers. Thus, past strong experiences modulate CV autonomic responses to acute acoustic stress.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
Autorzy:
Midro, Aleksandra
Gil, Krzysztof
Kurnik-Łucka, Magdalena
Jurczyk, Michał
Poniatowski, Adrian
Król, Magdalena
Opis:
Cancer is a growing public health problem; it is responsible annually for millions of deaths worldwide. Fluoropyrimidines are highly effective and commonly prescribed anti-neoplastic drugs used in a wide range of chemotherapy regimens against several types of malignancies. 5-fluorouracil and its prodrugs affect neoplastic cells in multiple ways by impairing their proliferation, principally through the inhibition of thymidylate synthase. Fluoropyrimidine-induced cardiotoxicity was described more than 50 years ago, but many details such as incidence, mechanisms, and treatment are unclear and remain disputed. Severe cardiotoxicity is not only life-threatening, but also leads to withdrawal from an optimal chemotherapy regimen and decreases survival rate. Differences in the frequency of cardiotoxicity are explained by different chemotherapy schedules, doses, criteria, and populations. Proposed pathophysiological mechanisms include coronary vasospasm, endothelial damage, oxidative stress, Krebs cycle disturbances, and toxic metabolites. Such varied pathophysiology of the cardiotoxicity phenomenon makes prevention and treatment more difficult. Cardiovascular disturbances, including chest pain, arrhythmias, and myocardial infarction, are among the most common side effects of this class of anti-neoplastic medication. This study aims to summarize the available data on fluoropyrimidine cardiotoxicity with respect to symptoms, incidence, metabolism, pathophysiological mechanism, diagnosis, management, and resistance.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
Wyświetlanie 1-10 z 37

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