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Wyszukujesz frazę "Kusak, Piotr" wg kryterium: Autor


Tytuł:
Dedicated devices and techniques : a cornerstone in recanalisation of chronic total occlusions of coronary arteries
Autorzy:
Dudek, Dariusz
Surowiec, Sławomir
Bryniarski, Leszek
Kusak, Piotr
Czarnecka, Danuta
Opis:
Recanalisation of chronic total occlusion (CTO) is still a challenge in invasive cardiology, requiring operator experience, equipment, and techniques dedicated to CTO. Due to difficulties in crossing the lesion by wire and by balloon (both responsible for 98% of the procedure’s failures), many helpful techniques have been described. We report the case of both Tornus system and anchor technique in successful recanalisation of a right coronary artery.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
Tytuł:
Activated factor IX, factor XI and tissue factor identify patients with permanent atrial fibrillation treated with warfarin who are at risk of ischemic stroke
Autorzy:
Plens, Krzysztof
Gissel, Matthew
Kusak, Piotr
Butenas, Saulius
Czarnecka, Danuta
Undas, Anetta
Opis:
Introduction: Previously, we have demonstrated that significant proportions of patients with various cardiovascular diseases have active tissue factor and active factor XIa in their plasma. In the current study, we evaluated active tissue factor and active factors (F)XI and FIX in plasma from patients with atrial fibrillation. Material and methods: In 110 consecutive patients with permanent atrial fibrillation receiving warfarin, we determined active tissue factor, together with plasma FIXa and FXIa, using clotting assays by measuring the response to inhibitory monoclonal antibodies. Results: Sixteen (14.5%) patients had detectable active tissue factor and active FXIa, including 11 subjects with both factors, while FIXa was observed in 28 (25.7%) patients. The three positive groups did not differ from the patients without these factors with regard to demographic and clinical characteristics. Von Willebrand factor was higher in the active tissue factor-positive group (p < 0.0001) and FXIa-positive group (p = 0.0037). Individuals positive for active tissue factor and FXIa had higher plasma interleukin-6 levels (p = 0.0014 and 0.0322, respectively). The presence of active tissue factor, FXIa and FIXa in anticoagulated patients with permanent atrial fibrillation correlated with elevated von Willebrand factor and interleukin-6. During a 3-year follow-up, ischemic stroke (n = 12, 10.9%) occurred more commonly among atrial fibrillation patients who had circulating TF (p = 0.002) or FXIa (p = 0.013). Conclusions: These data suggest that circulating active coagulation factors, in particular TF and FXIa, can be detected despite oral anticoagulation in a significant proportion of patients with atrial fibrillation, and could represent novel markers of persistent prothrombotic alterations predisposing to ischemic stroke.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł

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