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Tytuł:
Safer and efficient base editing and prime editing via ribonucleoproteins delivered through optimized lipid-nanoparticle formulations
Autorzy:
Palczewski, Krzysztof
Chen, Paul Z.
Kiser, Philip D.
Risalit,i Eleonora
Rodrigues Menezes, Carolline
Hołubowicz, Rafał
Smidak, Roman
Griffo Alessandra
Caprettini Valeria
Felgner, Philip L.
Dong, Zhiqian
Liu, David R.
Almeida Filipe
Lyon, David C.
Cheifet Barbara
Salom, David
Felgner, Jiin
Choi, Elliot H.
Palczewska, Grazyna
Bassetto, Marco
Du, Samuel W.
Haskell Jennifer
Gao, Fangyuan
Medani, Omar
Yan, Alexander L.
Hołubowicz, Maria W.
Newby, Gregory A.
Foik, Andrzej T.
Workman, J. Noah
Współwytwórcy:
Caprettini Valeria
Almeida Filipe
Cheifet Barbara
Griffo Alessandra
Haskell Jennifer
Wydawca:
Nature Portfolio
Cytata wydawnicza:
Hołubowicz, R., Du, S.W., Felgner, J. et al. Safer and efficient base editing and prime editing via ribonucleoproteins delivered through optimized lipid-nanoparticle formulations. Nat. Biomed. Eng 9, 57–78 (2025). https://doi.org/10.1038/s41551-024-01296-2
Opis:
Delivering ribonucleoproteins (RNPs) for in vivo genome editing is safer than using viruses encoding for Cas9 and its respective guide RNA. However, transient RNP activity does not typically lead to optimal editing outcomes. Here we show that the efficiency of delivering RNPs can be enhanced by cell-penetrating peptides (covalently fused to the protein or as excipients) and that lipid nanoparticles (LNPs) encapsulating RNPs can be optimized for enhanced RNP stability, delivery efficiency and editing potency. Specifically, after screening for suitable ionizable cationic lipids and by optimizing the concentration of the synthetic lipid DMG-PEG 2000, we show that the encapsulation, via microfluidic mixing, of adenine base editor and prime editor RNPs within LNPs using the ionizable lipid SM102 can result in in vivo editing-efficiency enhancements larger than 300-fold (with respect to the delivery of the naked RNP) without detectable off-target edits. We believe that chemically defined LNP formulations optimized for RNP-encapsulation stability and delivery efficiency will lead to safer genome editing.
Dostawca treści:
Repozytorium Centrum Otwartej Nauki
Artykuł
Tytuł:
Health Sector responses to the COVID-19 pandemic in Ontario, Canada – January to May 2020
Autorzy:
Bielska, Iwona A.
Manis, Derek R.
Schumacher, Connie
Moore, Emily
Lewis, Kaitlin
Agarwal, Gina
Mondoux, Shawn
Jewett, Lauren
Speicher, David J.
Liu, Rebecca H.
Leyenaar, Matthew
McLeod, Brent
Upadhye, Suneel
Tematy:
COVID-19
SARS-CoV-2
Ontario
Health Care Sector
Health Policy
sektor opieki zdrowotnej
polityka zdrowotna
Pokaż więcej
Wydawca:
Uniwersytet Jagielloński. Wydawnictwo Uniwersytetu Jagiellońskiego
Powiązania:
https://bibliotekanauki.pl/articles/63163469.pdf  Link otwiera się w nowym oknie
Opis:
The first positive case of COVID-19 in Canada was reported on January 25, 2020, in the city of Toronto, Ontario. Over the following four months, the number of individuals diagnosed with COVID-19 in Ontario grew to 28,263 cases. A state of emergency was announced by the Premier of Ontario on March 17, 2020, and the provincial health care system prepared for a predicted surge of COVID-19 patients requiring hospitalization. The Chief Medical Officer of Health and the Minister of Health guided the changes in the system in response to the evolving needs and science related to COVID-19. The pandemic required a rapid, concerted, and coordinated effort from all sectors of the system to optimize and maximize the capacity of the health system. The response to the pandemic in Ontario was complex with some sectors experiencing multiple outbreaks of COVID-19 (i.e. long-term care homes and hospitals). Notably, numerous sectors shifted to virtual delivery of care. By the end of May 2020, it was announced that hospitals would gradually resume postponed or cancelled services. This paper explores the impact of the COVID-19 pandemic on multiple health system sectors (i.e., public health, primary care, long-term care, emergency medical services, and hospitals) in Ontario from January to May 2020. Given the scope of the sectors contributing to the health system in Ontario, this analysis of a regional response to COVID-19 provides insight on how to improve responses and better prepare for future health emergencies.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Canada’s multi-jurisdictional COVID-19 Public Health response – January to May 2020
Autorzy:
Bielska, Iwona A.
Embrett, Mark
Jewett, Lauren
Buote, Richard
Manis, Derek R.
Parikh, Manasi
Speicher, David J.
Agarwal, Gina
Nartowski, Robert O.
Finnegan, Heather
Bandara, Thilina
Hamilton, Clayon B.
Moore, Emily
Liu, Rebecca H.
Roher, Sophie I. G.
Lopatina, Elena
Nguyen, Duyen Thi Kim
Lawrence, Logan
Lukewich, Julia
Tematy:
COVID-19
SARS-CoV-2
Canada
Public Health Response
Health Federalism
Kanada
działania zdrowia publicznego
federalism zdrowotny
Pokaż więcej
Wydawca:
Uniwersytet Jagielloński. Wydawnictwo Uniwersytetu Jagiellońskiego
Powiązania:
https://bibliotekanauki.pl/articles/63163460.pdf  Link otwiera się w nowym oknie
Opis:
In late January 2020, the first COVID-19 case was reported in Canada. By March 5, 2020, community spread of the virus was identified and by May 26, 2020, close to 86,000 patients had COVID-19 and 6,566 had died. As COVID-19 cases increased, provincial and territorial governments announced states of public health emergency between March 13 and 20, 2020. This paper examines Canada’s public health response to the COVID-19 pandemic during the first four months (January to May 2020) by overviewing the actions undertaken by the federal (national) and regional (provincial/territorial) governments. Canada’s jurisdictional public health structures, public health responses, technological and research endeavours, and public opinion on the pandemic measures are described. As the pandemic unravelled, the federal and provincial/territorial governments unrolled a series of stringent public health interventions and restrictions, including physical distancing and gathering size restrictions; closures of borders, schools, and non-essential businesses and services; cancellations of non-essential medical services; and limitations on visitors in hospital and long-term care facilities. In late May 2020, there was a gradual decrease in the daily numbers of new COVID-19 cases seen across most jurisdictions, which has led the provinces and territories to prepare phased re-opening. Overall, the COVID-19 pandemic in Canada and the substantial amount of formative health and policy-related data being created provide an insight on how to improve responses and better prepare for future health emergencies.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analysis of metagenomic data
Autorzy:
Francis, Dallace
Muralidharan, Harihara Subrahmaniam
Sharma, Nitesh Kumar
Pop, Mihai
Koslicki, David
Chikhi, Rayan
Zelikovsky, Alex
Błaszczyk, Dagmara
Ganda, Erika
Ronkowski, Cynthia
Kościółek, Tomasz
Rodriguez, Judith S.
Gancz, Abigail Shahar
Crandall, Keith A.
Ghiasi, Nika Mansouri
Łabaj, Paweł
Tierney, Braden T.
Van Syoc, Emily
Munteanu, Viorel
Sun, Fengzhu
Vicedomini, Riccardo
Alser, Mohammed
Mangul, Serghei
Luan, Tu
Rahnavard, Ali
Frolova, Alina
Jaiswal, Pooja
Mason, Christopher
Moustafa, Ahmed M.
Liu, Shaopeng
Andreace, Francesco
Blekhman, Ran
Zielińska, Kinga
Tian, Shuchang
Mutlu, Onur
Della Libera, Katja
Łabaj, Wojciech
Zackular, Joseph P.
Davenport, Emily R.
Huntley, Naomi E.
Opis:
Metagenomics has revolutionized our understanding of microbial communities, offering unprecedented insights into their genetic and functional diversity across Earth’s diverse ecosystems. Beyond their roles as environmental constituents, microbiomes act as symbionts, profoundly influencing the health and function of their host organisms. Given the inherent complexity of these communities and the diverse environments where they reside, the components of a metagenomics study must be carefully tailored to yield accurate results that are representative of the populations of interest. This Primer examines the methodological advancements and current practices that have shaped the field, from initial stages of sample collection and DNA extraction to the advanced bioinformatics tools employed for data analysis, with a particular focus on the profound impact of next-generation sequencing on the scale and accuracy of metagenomics studies. We critically assess the challenges and limitations inherent in metagenomics experimentation, available technologies and computational analysis methods. Beyond technical methodologies, we explore the application of metagenomics across various domains, including human health, agriculture and environmental monitoring. Looking ahead, we advocate for the development of more robust computational frameworks and enhanced interdisciplinary collaborations. This Primer serves as a comprehensive guide for advancing the precision and applicability of metagenomic studies, positioning them to address the complexities of microbial ecology and their broader implications for human health and environmental sustainability.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
Tytuł:
Asteroid sizes determined with thermophysical model and stellar occultations
Autorzy:
Libert, M.
Andersson, S.
Kulczak, P.
Horbowicz, J.
De Groot, H.
Schreurs, O.
Ellington, C.
Nosworthy, P.
Duffard, R.
Ferrais, M.
Carlson, N.
Oszkiewicz, D.
Takács, N.
Yamamura, H.
Geier, S.
Hirsch, R.
Csörnyei, G.
Murawiecka, M.
Ďurech, J.
Wünsche, N.
Collins, M.
Eleftheriou, M.
Pilcher, F.
Manna, A.
Lyzenga, G.
Rottenborn, M.
Frits, M.
Kretlow, M.
Ignácz, B.
Sonbas, E.
Liu, Y.
Dequinze, R.
Liu, R.
Polakis, T.
Błażewicz, D.
Filipek, M.
Skrzypek, J.
Ortiz-Ochoa, A. M.
Kankiewicz, P.
Monteiro, F.
Licandro, J.
Rutkowski, A.
Perig, V.
Żejmo, M.
Haymes, T.
Sobkowiak, K.
Agnetti, D.
Reddy, V.
Nadolny, J.
Hanna, W.
Zelený, P.
Sposetti, S.
Kaplan, M.
Nosal, P.
Mizutani, M.
Polák, J.
Swift, T.
Boninsegna, R.
Poláček, M.
Nikitin, V.
Nemoto, T.
Kudak, V.
Kamińska, M. K.
Tychoniec, Ł.
Szyszka, K.
Grice, J.
Marciniak, A.
Vida, K.
Bacci, R.
Eisfeldt, D.
Michniewicz, O.
Żukowski, K.
Lecossois, M.
Zawilski, M.
Higgins, D.
Bacci, P.
Messner, S.
Sárneczky, K.
Urakawa, S.
Skiff, B.
Bredner, E.
Gault, D.
Dogramatzidis, M.
Choukroun, A.
Baruffetti, P.
Dróżdż, M.
Kidd, S.
Rives, J.-J.
Pawłowski, M.
Stewart, C.
Golonka, J.
Smith, D.
Ogłoza, W.
Kubánek, J.
Saci, K.
Kim, M.-J.
Jehin, E.
Cseh, B.
Pál, A.
Antuszewicz, D.
Kalup, Cs.
Oey, J.
Petrescu, E.
Kirpluk, B.
Podlewska-Gaca, E.
Broughton, J.
Szakáts, R.
Beisker, W.
Stewart, W.
Horti-Dávid, Á.
Grazzini, L.
Anderson, C.
Konstanciak, I.
Jones, A.
Weber, C.
Dunham, D.
Miftah, M. A.
Jones, R.
Casalnuovo, G.
Harman, M.
Herald, D.
Delincak, P.
Gährken, B.
Hasubick, W.
Fini, P.
Maley, P.
Molnár, L.
Kattentidt, B.
Malagon, C.
Morales, N.
O’Connell, M.
Santana-Ros, T.
Galli, G.
Bora, Zs.
Denyer, P.
Choi, Y.-J.
Szkudlarek, M.
Ossola, A.
Guhl, K.
Leiva, R.
Borkowski, M.
Kamiński, K.
Cikota, S.
Pakštienė, E.
Fauvaud, M.
Maestripieri, M.
Yoshihara, H.
Popowicz, A.
Krannich, G.
Butkiewicz-Bąk, M.
Uno, M.
Gimple, B.
Polińska, M.
Sempronio, V.
Bertini, M.
Ruocco, N.
Lindner, P.
Casarramona, F.
Karagiannidis, A.
Newman, J.
Mieczkowska, I.
Kim, D.-H.
Benedyktowicz, L.
Fauvaud, S.
Zoła, Stanisław
Perła, J.
Arcoverde, P.
Aubry, R.-L.
Opis:
Context. The sizes of many asteroids, especially slowly rotating, low-amplitude targets, remain poorly constrained due to selection effects. These biases limit the availability of high-quality data, leaving size estimates reliant on spherical shape assumptions. Such approximations introduce significant uncertainties propagating, for example, into density determinations or thermophysical and compositional studies, affecting our understanding of asteroid properties. Aims. This work targets poorly studied main-belt asteroids, for most of which no shape models were previously available. Using only high-quality, dense light curves, thermal infrared observations (systematically including WISE data), and stellar occultations, we aimed to produce reliable shape models and scale them using two independent techniques, allowing for size comparison at the end. We conducted two observing campaigns to achieve this: one to obtain dense photometric light curves and another to acquire multi-chord stellar occultations by these objects. Methods. Shape and spin models were reconstructed using light curve inversion techniques. Sizes were determined via two methods: (1) advanced thermophysical modelling using the convex inversion thermophysical model (CITPM), which optimises spin and shape models to light curve data in the visible range together with infrared data, and (2) scaling the shape models with stellar occultations. Results. We obtained precise sizes and shape models for 15 asteroids. CITPM and occultation-derived sizes agree within 5% for most cases, demonstrating the reliability of the modelling approach. Larger discrepancies are usually linked to incomplete occultation chord coverage. The study also provides insights into surface properties, including albedo, surface roughness and thermal inertia. Conclusions. The use of high-quality data, coupled with an advanced TPM that uses both thermal and visible data while allowing the shape model to be adjusted according to both types of data, enabled us to determine sizes with precision comparable to those derived from multichord stellar occultations. We resolved substantial inconsistencies in previous size determinations for target asteroids, providing good input for future studies on asteroid densities and surface properties.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
Tytuł:
Family First: Evidence of Consistency and Variation in the Value of Family versus Personal Happiness across 49 Different Cultures
Autorzy:
Barrientos Marroquin, Pablo Eduardo
Kronberger, Nicole
Schwarz, Beate
Mustaffa, Nur Fariza
Işık, İdil
Gamsakhurdia, Vladimer
Denoux, Patrick
Kascakova, Natalia
Garðarsdóttir, Ragna
Røysamb, Espen
Mohorić, Tamara
Kosiarczyk, Aleksandra
Akotia, Charity
Igbokwe, David
Haas, Brian
Uchida, Yukiko
Sun, Chien-Ru
Liu, Xinhui
Sirlopú, David
Chun Yeung, June
Pavlović, Zoran
Kwiatkowska, Anna
Domínguez-Espinosa, Alejandra
Romashov, Vladyslav
Arevalo, Douglas
L. Vignoles, Vivian
Mosca, Oriana
Esteves, Carla Sofia
Lee, J. Hannah
Maricchiolo, Fridanna
Okvitawanli, Ayu
Klůzová Kračmárová, Lucie
Hanke-Boerr, Diana
Pavlopoulos, Vassilis
Serdarevich, Ursula
Malyonova, Arina
Nadi, Azar
Xing, Cai
Nader, Martin
Selim, Heyla
Poláčková Šolcová, Iva
van Tilburg, Wijnand
Bond, Michael
Miu-Chi Lun, Vivian
Kryś, Kuba
Sargautyte, Ruta
Zelenski, John
Teyssier, Julien
Murdock, Elke
Charkviani, Salome
Baltin, Arno
Fülöp, Márta
Gavreliuc, Alin
Adamovic, Mladen
Vauclair, Christin-Melanie
Appoh, Lily
Park, Joonha
Rizwan, Muhammad
Torres, Claudio
van Osch, Yvette
Kocimska-Zych, Agata
Igou, Eric R.
Wydawca:
SAGE Publications
Cytata wydawnicza:
Krys, K., Yeung, J.Ch., Haas, B.W., van Osch, Y., Kosiarczyk, A., Kocimska-Zych, A., Torres, C., Selim, H.A., Zelenski, J.M., Bond, M.H., Park, J., Lun, V.M.-Ch., Maricchiolo, F., Vauclair, Ch.-M., Šolcová, I.P., Sirlopú, D., Xing, C., Vignoles, V.L., van Tilburg, W.A.P., Teyssier, J., Sun, Ch.-R., Serdarevich, U., Schwarz, B., Sargautyte, R., Røysamb, E., Romashov, V., Rizwan, M., Pavlović, Z., Pavlopoulos, V., Okvitawanli, A., Nadi, A., Nader, M., Mustaffa, N.F., Murdock, E., Mosca, O., Mohorić, T., Barrientos Marroquin, P.E., Malyonova, A., Liu, X., Lee, J.H., Kwiatkowska, A., Kronberger, N., Kráčmarová, L.K., Kascakova, N., Işık, İ., Igou, E.R., Igbokwe, D.O., Hanke-Boer, D., Gavreliuc, A., Garðarsdóttir, R.B., Fülöp, M., Gamsakhurdia, V., Esteves, C.S.,Domínguez-Espinosa, A., Denoux, P., Charkviani, S., Baltin, A., Arevalo, D., Appoh,
Opis:
People care about their own well-being, but also about the well-being of their families. It is currently however unknown how much people tend to value their own and their family’s wellbeing. A recent study documented that people value family happiness over personal happiness across four cultures. In this study, we sought to replicate this finding across a larger sample size (N = 12,819) and a greater number of countries (N = 49). We found that the strength of the idealization of family over personal happiness preference was small (average Cohen’s ds = .20, range -.02 to.48), but present in 98% of the studied countries, with statistical significance in 73- 75%, and variance across countries < 2%. We also found that the size of this effect did vary somewhat across cultural contexts. In Latin American cultures highest on relational mobility, the idealization of family over personal happiness was very small (average Cohen’s ds for Latin America = .15 and .18), while in Confucian Asia cultures lowest on relational mobility, this effect was closer to medium (ds > .40 and .30). Importantly, we did not find strong support for traditional theories in cross-cultural psychology that associate collectivism with greater prioritization of the family versus the individual; country level individualism-collectivism was not associated with variation in the idealization of family versus individual happiness. Our findings indicate that no matter how much various populists abuse the argument of “protecting family life” to disrupt emancipation, family happiness seems to be a pan-culturally phenomenon. Family well-being is a key ingredient of social fabric across the world, and should be acknowledged by psychology and well-being researchers, and by progressive movements too.
Polish National Science Centre under grant 2020/38/E/HS6/00357; the Hungarian OTKA under grant K-135963; the Brazilian National Council for Scientific and Technological Development – CNPq under grant 301298/2018-1; the Czech Science Foundation CSF under grant 20-08583S, by the NPO, Systemic Risk Institute, LX22NPO5101; and the Ministry of Higher Education and Science RF FZEW-2020-0005.
Dostawca treści:
Repozytorium Centrum Otwartej Nauki
Artykuł
Tytuł:
Family First: Evidence of Consistency and Variation in the Value of Family versus Personal Happiness across 49 Different Cultures
Autorzy:
Barrientos Marroquin, Pablo Eduardo
Kronberger, Nicole
Schwarz, Beate
Işık, İdil
Gamsakhurdia, Vladimer
Denoux, Patrick
Kascakova, Natalia
Garðarsdóttir, Ragna
Røysamb, Espen
Nur Fariza, Mustaffa
Mohorić, Tamara
Kosiarczyk, Aleksandra
Akotia, Charity
Igbokwe, David
Haas, Brian
Uchida, Yukiko
Sun, Chien-Ru
Liu, Xinhui
Sirlopú, David
Chun Yeung, June
Pavlović, Zoran
Kwiatkowska, Anna
Domínguez-Espinosa, Alejandra
Romashov, Vladyslav
Arevalo, Douglas
L. Vignoles, Vivian
Mosca, Oriana
Esteves, Carla Sofia
Lee, J. Hannah
Maricchiolo, Fridanna
Okvitawanli, Ayu
Klůzová Kračmárová, Lucie
Hanke-Boerr, Diana
Pavlopoulos, Vassilis
Serdarevich, Ursula
Malyonova, Arina
Nadi, Azar
Xing, Cai
Nader, Martin
Selim, Heyla
Poláčková Šolcová, Iva
van Tilburg, Wijnand
Bond, Michael
Miu-Chi Lun, Vivian
Kryś, Kuba
Sargautyte, Ruta
Zelenski, John
Teyssier, Julien
Murdock, Elke
Charkviani, Salome
Baltin, Arno
Fülöp, Márta
Gavreliuc, Alin
Adamovic, Mladen
Vauclair, Christin-Melanie
Appoh, Lily
Park, Joonha
Rizwan, Muhammad
Torres, Claudio
van Osch, Yvette
Kocimska-Zych, Agata
Igou, Eric R.
Wydawca:
SAGE Publications
Cytata wydawnicza:
Krys, K., Chun Yeung, J., Haas, B. W., van Osch, Y., Kosiarczyk, A., Kocimska-Zych, A., Torres, C., Selim, H. A., Zelenski, J. M., Bond, M. H., Park, J., Lun, V. M.-C., Maricchiolo, F., Vauclair, C.-M., Poláčková Šolcová, I., Sirlopú, D., Xing, C., Vignoles, V. L., van Tilburg, W. A. P., … Uchida, Y. (2023). Family First: Evidence of Consistency and Variation in the Value of Family Versus Personal Happiness Across 49 Different Cultures. Journal of Cross-Cultural Psychology, 54(3), 323-339. https://doi.org/10.1177/00220221221134711
Opis:
People care about their own well-being, but also about the well-being of their families. It is currently however unknown how much people tend to value their own and their family’s wellbeing. A recent study documented that people value family happiness over personal happiness across four cultures. In this study, we sought to replicate this finding across a larger sample size (N = 12,819) and a greater number of countries (N = 49). We found that the strength of the idealization of family over personal happiness preference was small (average Cohen’s ds = .20, range -.02 to.48), but present in 98% of the studied countries, with statistical significance in 73- 75%, and variance across countries < 2%. We also found that the size of this effect did vary somewhat across cultural contexts. In Latin American cultures highest on relational mobility, the idealization of family over personal happiness was very small (average Cohen’s ds for Latin America = .15 and .18), while in Confucian Asia cultures lowest on relational mobility, this effect was closer to medium (ds > .40 and .30). Importantly, we did not find strong support for traditional theories in cross-cultural psychology that associate collectivism with greater prioritization of the family versus the individual; country level individualism-collectivism was not associated with variation in the idealization of family versus individual happiness. Our findings indicate that no matter how much various populists abuse the argument of “protecting family life” to disrupt emancipation, family happiness seems to be a pan-culturally phenomenon. Family well-being is a key ingredient of social fabric across the world, and should be acknowledged by psychology and well-being researchers, and by progressive movements too.
This work was supported by the Polish National Science Centre under grant 2020/38/E/HS6/00357; the Hungarian OTKA under grant K-135963; the Brazilian National Council for Scientific and Technological Development – CNPq under grant 301298/2018-1; the Czech Science Foundation CSF under grant 20-08583S, by the NPO, Systemic Risk Institute, LX22NPO5101; and the Ministry of Higher Education and Science RF FZEW-2020-0005.
Dostawca treści:
Repozytorium Centrum Otwartej Nauki
Artykuł
Tytuł:
What makes a theory of consciousness unscientific?
Autorzy:
Seitz, Aaron R.
Rademaker, Rosanne L.
Bengio, Yoshua
Kwok, Sze Chai
Garfinkel, Sarah
Wierzchoń, Michał
Solovey, Guillermo
Charest, Ian
Stein, Timo
Pereplyotchik, David
Schmitz, Michael
Heyes, Cecilia
Frith, Chris D.
Schiller, Daniela
Bisley, James W.
Spiers, Hugo
Kording, Konrad
Carruthers, Peter
Cherkaoui, Mouslim
Odegaard, Brian
Owen, Adrian M.
Carmel, David
Doerig, Adrien
Hassin, Ran R.
Mok, Robert M.
Hsieh, Po-Jang
Ringach, Dario L.
Martinez-Trujillo, Julio
Silvanto, Juha
Bekinschtein, Tristan A.
Or, Charles C.-F.
Shepherd, Joshua
Cheng, Tony
Sebastián, Miguel Ángel
Mobbs, Dean
Carrasco, Marisa
Dennett, Daniel C.
Taschereau-Dumouchel, Vincent
Herzog, Michael H.
Metcalfe, Janet
Tse, Peter U.
Pestilli, Franco
Browning, Jacob
Knapen, Tomas
Frankish, Keith
Slagter, Heleen A.
De Brigard, Felipe
Fleming, Stephen M.
Cumming, Sam
Lieberman, Matthew D.
Schwarzkopf, D. Samuel
Kvamme, Timo L.
Hanson, Jake R.
LeDoux, Joseph
Dijkstra, Nadine
Tong, Frank
Baxter, Mark G.
Buonomano, Dean
Smith, Barry C.
Phillips, Ian
Arnold, Derek H.
Mylopoulos, Myrto
Vibell, Jonas
Cushing, Cody A.
Goodale, Melvyn A.
Miller, Kenneth D.
de Gelder, Beatrice
Kentridge, Robert
Soto, David
Cohen, Michael A.
Carter, Olivia
Corlett, Philip R.
Liu, Ka-Yuet
Watzl, Sebastian
Schurger, Aaron
Weisberg, Josh
Rees, Geraint
Morales, Jorge
Libedinsky, Camilo
Christoff, Kalina
Gottlieb, Jacqueline
Lee, Alan L. F.
Lanfranco, Renzo C.
Webb, Taylor
Konstantinou, Nikos
Machizawa, Maro G.
Klincewicz, Michał
Snyder, Joel S.
Hung, Shao-Min
Scott, Ryan B.
Yan, Karen
Chang, Dorita H. F.
Rahnev, Dobromir
Dux, Paul E.
Roskies, Adina
Wheatley, Thalia
Mitra, Partha P.
Peters, Megan A. K.
Cleeremans, Axel
Lau, Hakwan
Michel, Matthias
Lin, Ying-Tung
Wokke, Martijn E.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
Tytuł:
Hot QCD white paper
Autorzy:
Perepelitsa, D. V.
O'Brien, E.
Zajc, W. A.
Niida, T.
Yee, H. -U.
Wang, F.
Ratti, C.
Shi, Z.
Bock, F.
Schäfer, T.
Narde, A.
Koch, V.
Finger Jr., M.
Putschke, J.
Berdnikov, Y.
Ramasubramanian, N. V.
Bossi, H.
Drees, A.
Salur, S.
Voloshin, S. A.
Ye, Z.
Schenke, B.
Lajoie, J. G.
Morrison, D. P.
Judd, E. G.
Yao, X.
Shen, C.
Hong, B.
Caines, H.
Jacak, B. V.
Praszałowicz, Michał
Kotov, D.
Odyniec, G.
Evdokimov, O.
Timmins, A. R.
Bautista, I.
Jheng, H. R.
Karpenko, I.
Song, H.
Knospe, A. G.
Jahan, J.
Blair, J. T.
Tribedy, P.
Yang, Y.
Luo, X.
Teaney, D.
Videbæk, F.
Durham, J. M.
Boimska, B.
Liu, M. X.
Khachatryan, V.
Dexheimer, V.
Lim, S. H.
Okorokov, V. A.
Schmidt, N. V.
Loizides, C.
Csanád, M.
Osborn, J. D.
Reed, R.
Kharzeev, D. E.
Thomas, D.
Ruan, L.
Jeon, S.
Majumder, A.
Seger, J.
Gonzalez, V.
Soudi, I.
Chen, Y.
Minafra, N.
Menon, A. S.
Xie, W.
Nagle, J. L.
Kimelman, B.
Dash, A. P.
Schmier, A.
Bielcik, J.
Becattini, F.
Rueda, O. V.
Stephanov, M.
Luzum, M.
Tapia Takaki, D.
Venugopalan, R.
Nouicer, R.
Royon, C.
Steinberg, P.
Hachiya, T.
Dehmelt, K.
Mueller, B.
Dong, X.
Ma, R.
Mehtar-Tani, Y.
Petreczky, P.
Greene, S. V.
Frawley, A. D.
Geurts, F.
Chien, Y. -T.
He, X.
Sumbera, M.
Klein, S. R.
Rosati, M.
Tu, Z.
Heinz, U.
Klay, J. L.
Strickland, M.
Weyhmiller, S.
Stahl Leiton, A. G.
Noronha-Hostler, J.
Krintiras, G. K.
Rinn, T.
Read, K. F.
Tang, A. H.
Mak, S.
Novitzky, N.
Gale, C.
Ivanishchev, D.
Ehlers, R. J.
Likmeta, I.
Mignerey, A. C.
Arslandok, M.
Noronha, J.
Sakaguchi, T.
Frantz, J.
Grau, N.
Singh, M.
Smith, K. L.
Sarsour, M.
Bellwied, R.
Seto, R
Smirnov, N.
Park, S.
Vovchenko, V.
Humanic, T. J.
Liao, J.
Elfner, H.
Sickles, A. M.
Singh, B. K.
Bass, S. A.
Beattie, C.
Kim, M.
Kuo, C. M.
Grossberndt, S. K.
Baty, A. A.
Wang, X. -N.
Kapusta, J. I.
Berdnikov, A.
Nattrass, C. E.
Vujanovic, G.
Shulga, E.
Velkovska, J.
Chiu, M.
Finger, M.
Sunar Cerci, D.
Connors, M. E.
Rebello Teles, P.
Jia, J.
Wang, X.
David, G.
Paquet, J. -F.
Rapp, R.
Tuo, S.
Du, L.
Kunnawalkam Elayavalli, R.
Lee, Y. -J.
Longo, R.
Xu, N.
Markert, C.
Pruneau, C.
Parotto, P.
Pinkenburg, C.
Sheibani, Oveis
Tachibana, Y.
da Silva, C. L.
Li, W.
Roland, G.
Opis:
Hot QCD physics studies the nuclear strong force under extreme temperature and densities. Experimentally these conditions are achieved via high-energy collisions of heavy ions at the Relativistic Heavy Ion Collider (RHIC) and the Large Hadron Collider (LHC). In the past decade, a unique and substantial suite of data was collected at RHIC and the LHC, probing hydrodynamics at the nucleon scale, the temperature dependence of the transport properties of quark-gluon plasma, the phase diagram of nuclear matter, the interaction of quarks and gluons at different scales and much more. This document, as part of the 2023 nuclear science long range planning process, was written to review the progress in hot QCD since the 2015 Long Range Plan for Nuclear Science, as well as highlight the realization of previous recommendations, and present opportunities for the next decade, building on the accomplishments and investments made in theoretical developments and the construction of new detectors. Furthermore, this document provides additional context to support the recommendations voted on at the Joint Hot and Cold QCD Town Hall Meeting, which are reported in a separate document.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
Wyświetlanie 1-10 z 31

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