Autor: Liu, Fang - Prolib Integro

Skocz do pozycji: 1.

Tytuł:: In vitro co-stimulation of anti-tumor activity by soluble B7 molecules
Autorzy:: He, Wei
Hu, Zhong-Bo
Liu, Fang
Feng, Xian-Qi
Zou, Ping
Tematy:: immunotherapy
tumor escape
gene fusion
recombinant fusion proteins; Pokaż więcej
Wydawca:: Polskie Towarzystwo Biochemiczne
Powiązania:: https://bibliotekanauki.pl/articles/1041178.pdf Link otwiera się w nowym oknie
Opis:: In order to investigate the anti-tumor activity of a soluble B7-1/immunoglobulin G fusion protein and explore an effective method to eliminate immune escape of tumor cells, a recombinant vector encoding this fusion protein was constructed and constitutively expressed in Chinese hamster ovary cells. After purification with protein G affinity chromatography, the soluble fusion protein was tested for bioactivity. Results showed that the fusion protein could significantly increase the density of B7-1 molecules on WEHI-3 cells, a mouse leukemia cell line. Through allogeneic mixed lymphocyte tumor cultures, it was demonstrated that, with the presence of the first signal, it could also significantly enhance T cell activation and killing activity against WEHI-3 cells and interleukin-2 secretion by activated mouse T lymphocytes. The conclusion can be drawn that the soluble B7-IgG fusion protein has a potent capacity to generate or enhance anti-tumor immune response in vitro, and its clinical value deserves further investigation.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Upregulation of GRP78 and caspase-12 in diastolic failing heart
Autorzy:: Sun, Yingying
Liu, Guanghui
Song, Tao
Liu, Fang
Kang, Weiqiang
Zhang, Yun
Ge, Zhiming
Tematy:: caspase-12
diastolic heart failure
GRP78; hypertension
apoptosis; Pokaż więcej
Wydawca:: Polskie Towarzystwo Biochemiczne
Powiązania:: https://bibliotekanauki.pl/articles/1040708.pdf Link otwiera się w nowym oknie
Opis:: Background: The endoplasmic reticulum (ER) fulfills multiple cellular functions. Various stimuli can potentially cause ER stress (ERS). ERS is one of the intrinsic apoptosis pathways and apoptosis plays a critical role in hypertension. Glucose regulated protein 78 (GRP78) has been widely used as a marker for ERS and caspase-12 mediated apoptosis was a specific apoptotic pathway of ER. The expression of GRP78 and caspase-12 remains poorly understood in the diastolic heart failure resulting from hypertension. Methods: We used spontaneously hypertensive rats (SHRs) to establish a model of diastolic heart failure, and performed immunohistochemistry, western blot, and real-time PCR to analyze GRP78 and caspase-12. Results: We found that GRP78 and caspase-12 had enhanced expression at protein and mRNA levels. Conclusions: These results suggest that GRP78 and caspase-12 were upregulated in cardiomyocytes and ERS can contribute to cardiac myocyte apoptosis in the diastolic heart failure resulting from hypertension.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Investigations on a novel collector for anionic reverse flotation separation of quartz from iron ores
Autorzy:: Fang, Ji
Ge, Yingyong
Liu, Shunbing
Yu, Jun
Liu, Cheng
Tematy:: reverse flotation
iron ore
quartz
collector
fatty acid; Pokaż więcej
Wydawca:: Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Powiązania:: https://bibliotekanauki.pl/articles/1448585.pdf Link otwiera się w nowym oknie
Opis:: It is necessary to exploit an easy and effective way to obtain flotation collector. In this paper, oleic acid was modified by oxidation reaction to obtain an excellent collector. The ﬂotation performances of oleic acid and its oxidation products were systematically investigated and a novel collector ((E)-8,11-dihydroperoxyoctadec-9-enoic acid, EDEA) was obtained. Single mineral flotation tests results showed that EDEA had strong flotation power towards quartz at pH＞11 and hardly floated hematite and magnetite at pH=8~13. The recovery of quartz could achieve 92.35% with 120 mg/L EDEA under the condition of pH=12 and dosage of $CaCl_2$ 60mg/L while the recovery was 62.44% with 120 mg/L oleic acid. Bench scale flotation tests results showed that EDEA had a preferable effect on separating quartz from iron ore especially at low flotation temperature (288K). The mechanism research revealed that EDEA attracted on quartz surface through electrostatic attraction and the neighboring EDEA molecules could form intermolecular hydrogen bonds which resulted in a closer alignment of EDEA on quartz surface.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Research on the maritime logistics pricing model of risk-averse retailer-dominated dual-channel supply chain
Autorzy:: Fang, Q.
Tong, Z.
Ren, L.
Liu, A.
Tematy:: dual channel
risk-averse
retailer-dominated
supply chain; Pokaż więcej
Wydawca:: Politechnika Gdańska. Wydział Inżynierii Mechanicznej i Okrętownictwa
Powiązania:: https://bibliotekanauki.pl/articles/258648.pdf Link otwiera się w nowym oknie
Opis:: Price decision is studied in a risk-averse retailer-dominated dual-channel supply chain, which consisting of one manufacturers and one retailer with both off-line and on-line channels. Firstly, two mean-variance models in centralized and decentralized supply chain are established. Secondly, the optimal solutions under the two decision modes are compared and analyzed. The results shows that the price of dual-channel of retailer decreased with the increase of retailers’ risk- aversion coefficient and the standard deviation of the fluctuation of market demand, while the wholesale price changes is on the contrary; in addition, when the market demand is greater than a certain value, the prices of dual channel are correspondingly higher in decentralized supply chain than in centralized supply chain, and vice versa. In addition, when the retailer’s risk aversion is in a certain interval, the expected utility of the whole supply chain is greater in centralized supply chain than in decentralized decision, and vice versa. Finally, a numerical example is given to verify the above conclusions.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 5.

Tytuł:: Accurate Frequency Estimation Based On Three-Parameter Sine-Fitting With Three FFT Samples
Autorzy:: Liu, X.
Ren, Y.
Chu, C.
Fang, W.
Tematy:: frequency estimation
CRLB
three-parameter sine-fitting
RMSE
golden section; Pokaż więcej
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Powiązania:: https://bibliotekanauki.pl/articles/220451.pdf Link otwiera się w nowym oknie
Opis:: This paper presents a simple DFT-based golden section searching algorithm (DGSSA) for the single tone frequency estimation. Because of truncation and discreteness in signal samples, Fast Fourier Transform (FFT) and Discrete Fourier Transform (DFT) are inevitable to cause the spectrum leakage and fence effect which lead to a low estimation accuracy. This method can improve the estimation accuracy under conditions of a low signal-to-noise ratio (SNR) and a low resolution. This method firstly uses three FFT samples to determine the frequency searching scope, then – besides the frequency – the estimated values of amplitude, phase and dc component are obtained by minimizing the least square (LS) fitting error of three-parameter sine fitting. By setting reasonable stop conditions or the number of iterations, the accurate frequency estimation can be realized. The accuracy of this method, when applied to observed single-tone sinusoid samples corrupted by white Gaussian noise, is investigated by different methods with respect to the unbiased Cramer-Rao Low Bound (CRLB). The simulation results show that the root mean square error (RMSE) of the frequency estimation curve is consistent with the tendency of CRLB as SNR increases, even in the case of a small number of samples. The average RMSE of the frequency estimation is less than 1.5 times the CRLB with SNR = 20 dB and N = 512.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 6.

Tytuł:: An ultra-wideband plasmonic reflector based on local resonant bandgap and Bragg bandgap
Autorzy:: Chen, San
Fang, Liang
Liu, Jianqiang
Wu, Shan
Tematy:: metal-insulator-metal waveguides
SRRs
split ring resonators
Bragg bandgap
local resonant bandgap; Pokaż więcej
Wydawca:: Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Powiązania:: https://bibliotekanauki.pl/articles/58970368.pdf Link otwiera się w nowym oknie
Opis:: Unlike previous reports that utilized periodic modulation of insulation layer thickness or dielectrics, we propose the use of split ring resonators (SRRs) and their arrays to modulate the propagation characteristics of MIM plasmon waveguides. Due to the strong resonance backscattering of SRR, resonance transmission valleys appear in the transmission spectra of MIM waveguides. Changing the size of SRR can achieve continuously adjustable positions of resonance transmission valleys. The introduction of SRRs periodic arrays will result in two bands (bandgaps) with transmission minimum in the transmission spectra. Combining the dependence of the two bandgaps on the array period and the field distribution, the two bandgaps are Bragg bandgaps and local resonance bandgaps, respectively. By modulating the local resonance bandgap, the Bragg bandgap can be tuned. The introduction of local bandgap increases the degree of freedom to modulate the transmission characteristics of MIM waveguides. Combining local resonant bandgap and Bragg bandgap can significantly increase the reflection bandwidth, achieve broadband filtering, and facilitate the miniaturization of waveguide devices.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 7.

Tytuł:: Reliability analysis of subway sliding plug doors based on improved FMECA and Weibull distribution
Autorzy:: Wang, Weibo
Liu, Wenxiu
Fang, Yu
Zheng, Yongkang
Lin, Chuan
Jiang, Yonghua
Liu, Dong
Tematy:: subway sliding plug door
improved FMECA
DUOWA operator
AHP
Weibull distribution; Pokaż więcej
Wydawca:: Polska Akademia Nauk. Polskie Naukowo-Techniczne Towarzystwo Eksploatacyjne PAN
Powiązania:: https://bibliotekanauki.pl/articles/59112783.pdf Link otwiera się w nowym oknie
Opis:: Using traditional failure mode effects and criticality analysis (FMECA) to analyze the hazard of subway sliding plug door system, there are problems such as easy-to-take repetitive values, irrational allocation of expert's weights, and failure to consider the weights of evaluation factors. To address the above problems, this paper proposes an improved FMECA by using linear interpolation to increase the differentiation of the same fault probability occurrence among various fault modes. Apply the dependent uncertain ordered weighted averaging (DUOWA) algorithm to assign weights to different experts dynamically. The analytic hierarchy process (AHP) is used to endow weights to diverse evaluation factors to make them more suitable for engineering needs. We collected 1,836 days of metro train operation records from the Shanghai subway manufacturing plant and studied 17 common faults. Next, use a reliability-centered maintenance (RCM) strategy to determine maintenance periods for different fault modes. Finally, through the Weibull distribution fitting test, the fault rate function of the door is obtained, and the remaining useful life (RUL) of the door is predicted. The consistency between the vulnerable parts obtained by our proposed method and the statistics of the maintenance records of the subway sliding plug door verifies the effectiveness and reliability of our improved FMECA.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 8.

Tytuł:: Improved virtual space vector modulation for neutral point voltage oscillation and common-mode voltage reduction in neutral point clamped three-level inverter
Autorzy:: Fang, Junlong
Wang, Guangya
Li, Ran
Liu, Siyuan
Wang, Shuyu
Tematy:: three-level inverter
vector conversion
virtual space vector modulation
falownik trójpoziomowy
konwersja wektorowa
modulacja wektora przestrzeni wirtualnej; Pokaż więcej
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Powiązania:: https://bibliotekanauki.pl/articles/1841339.pdf Link otwiera się w nowym oknie
Opis:: The neutral point clamped (NPC) three-level inverter is widely used in high-voltage and high-power applications. However, neutral point voltage oscillation (NPVO) and common-mode voltage (CMV) problems exist in the NPC three-level inverter. In this paper, an improved virtual space vector modulation (VSVM) is proposed based on the reconstruction of a virtual small vector and a virtual medium vector. Compared with the traditional VSVM, an improved VSVM can effectively reduce the CMV. On this basis, a vector conversion method is proposed to further reduce the NPVO in the whole range. Simulation results verify the effectiveness and superiority of the improved VSVM.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 9.

Tytuł:: Balancing reliability and maintenance cost rate of multi-state components with fault interval omission
Równoważenie wskaźników niezawodności i kosztów utrzymania elementów wielostanowych z pominięciem przedziału wystąpienia uszkodzenia
Autorzy:: Dong, Wenjie
Liu, Sifeng
Yang, Xiaoyu
Wang, Huan
Fang, Zhigeng
Tematy:: multi-state systems (MSSs)
fault effect omission
stochastic process
repairable model
maintenance cost rate
systemy wielostanowe (MSS)
pominięcie wpływu uszkodzenia
proces stochastyczny
model naprawialny
polityka utrzymania ruchu; Pokaż więcej
Wydawca:: Polska Akademia Nauk. Polskie Naukowo-Techniczne Towarzystwo Eksploatacyjne PAN
Powiązania:: https://bibliotekanauki.pl/articles/301323.pdf Link otwiera się w nowym oknie
Opis:: For the repairable multi-state component, reliability indexes are analyzed based on a homogenous Continuous Time Markov Chain (CTMC). If the component can work well when its repair time is sufficiently short, a threshold value for maintenance is introduced. When the fault interval is less than threshold time, the fault effect is considered neglected. In this paper, comparisons of availability show differences of the new model and the original model with or without fault interval omission. In addition, balancing the maintenance cost and lifetime of multi-state components is an important issue when threshold values are considered. Both constants and non-negative random variables are modeled respectively. Finally, numerical examples are presented to illustrate the results obtained in this paper.
W przypadku naprawialnych elementów wielostanowych, wskaźniki niezawodności analizuje się w oparciu o łańcuch Markowa z czasem ciągłym. Jeśli element może działać prawidłowo, mimo uszkodzenia, dzięki wystarczająco krótkiemu czasowi naprawy, wprowadza się próg czasowy dla konserwacji. Gdy przedział czasu, w którym następuje uszkodzenie jest krótszy niż próg czasowy dla działań konserwacyjnych, wpływ uszkodzenia uważa się za nieistotny. Przeprowadzone w niniejszym artykule porównania gotowości wykazały różnice między nowym modelem a modelem oryginalnym z pominięciem lub bez pominięcia przedziału wystąpienia uszkodzenia. Ponadto, przy rozważaniu wartości progowych, ważną kwestią jest równoważenie kosztów utrzymania i żywotności elementów wielostanowych. W pracy próg wystąpienia uszkodzenia zamodelowano, odpowiednio, zarówno jako wartość stałą jak i nieujemną zmienną losową. Na koniec przedstawiono przykłady ilustrujące wyniki przedstawionych badań.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 10.

Tytuł:: Intelligent Design Suggestion and Sales Forecasting for New Products in the Apparel Industry
Autorzy:: Vu, Thuy-Linh
Tsao, Yu-Chung
Fang, I-Wen
Liu, Yu-Hsuan
Wydawca:: Sciendo
Cytata wydawnicza:: Tsao, Y.C., Liu, Y.H., Vu, T.L. & Fang, I.W. Intelligent Design Suggestion and Sales Forecasting for New Products in the Apparel Industry. Fibres & Textiles in Eastern Europe, 2023, Sciendo, vol. 31 no. 6, pp. 30-38. https://doi.org/10.2478/ftee-2023-0052
Opis:: This study demonstrates how algorithms can assist humans in decision-making in the apparel industry. A two-stage method including suggestions and intelligent forecasting was proposed. In the first stage, a web crawler was used to browse a B2C apparel website to identify popular products. In the second stage, machine learning methods were used to predict the sales demand for new products. Additionally, we used Google Trends to collect external information indices to adjust the demand forecasting. Our numerical study shows that the intelligent forecasting approach can effectively reduce the Mean Square Error (MSE), Root Mean Square Error (RMSE), and Mean Absolute Percentage Error (MAPE) by at least 45.79, 26.35, and 26.34 %, respectively.
Dostawca treści:: Repozytorium Centrum Otwartej Nauki

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