Autor: Lozano, I. - Prolib Integro

Skocz do pozycji: 1.

Tytuł:: Youngest agamid lizards from Western Europe (Sierra de Quibas, Spain, late Early Pleistocene)
Autorzy:: Blain, H.-A.
Bailon, S.
Agusti, J.
Pinero-Garcia, P.
Lozano-Fernandez, I.
Sevilla, P.
Lopez-Garcia, J.M.
Sanchez, G.R.
Mancheno, M.A.
Wydawca:: Polska Akademia Nauk. Instytut Paleobiologii PAN
Powiązania:: https://bibliotekanauki.pl/articles/21138.pdf Link otwiera się w nowym oknie
Opis:: Here we report a new Early Pleistocene record of agamid lizards (Agamidae indet.) from the Spanish locality of Quibas (ca. 1.3–1.0 Ma), which represents the latest evidence of the family in Western Europe. Up to now, the family Agamidae was considered to have disappeared in this region at 1.8 Ma. This new record implies the survival of agamid lizards for a large part of the Early Pleistocene in the southernmost Iberian Peninsula, probably because of favourable climatic and environmental conditions. Consequently, the formerly detected Pliocene / Pleistocene boundary is no longer recognisable in the evolution of the herpetological assemblages in Western Europe.
Dostawca treści:: Biblioteka Nauki

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Tytuł:: MAGIC gamma-ray and multi-frequency observations of flat spectrum radio quasar PKS 1510−089 in early 2012
Autorzy:: Noda, K.
Zanin, R.
Bonnefoy, S.
Bangale, P.
Surić, T.
Manilla-Robles, A.
Carosi, A.
Bednarek, W.
Delgado Mendez, C.
Torres, D. F.
Zarpudin, B.
Bretz, T.
Hrupec, D.
La Barbera, A.
Ribó, M.
Treves, A.
Raiteri, C. M.
Schultz, C.
Villata, M.
Steinbring, T.
Lähteenmäki, A.
Chen, W. P.
Carnerero, M. I.
López-Oramas, A.
Readhead, A. C. S.
Satalecka, K.
Uellenbeck, M.
Barrio, J. A.
Temnikov, P.
Tammi, J.
Scapin, V.
Kellermann, H.
Marscher, A.
Partini, S.
Ansoldi, S.
López, M.
Verrecchia, F.
Aller, M. F.
Morozova, D. A.
Saito, T.
Orienti, M.
Dazzi, F.
Dominis Prester, D.
Doert, M.
Maneva, G.
Biland, A.
Barres de Almeida, U.
Font, L.
Mazin, D.
Shore, S. N.
Molina, S. N.
Nilsson, K.
Fuhrman, L.
Mallot, K.
Sitarek, J.
Dorner, D.
Nestoras, I.
Godinović, N.
Bonnoli, G.
Borracci, F.
Gurwell, M. A.
Lewandowska, N.
Fruck, C.
Kadenius, V.
Kurtanidze, S. O.
Hayashida, M.
Ferenc, D.
Gaug, M.
Ovcharov, E.
Tornikoski, M.
Hovatta, T.
Krause, J.
Konstantinova, T. S.
Overkemping, A.
Paredes-Fortuny, X.
Makariev, M.
Antoranz, P.
Marcote, B.
Takami, H.
Wagner, R. M.
Chigladze, R. A.
Mirzoyan, R.
Reinthal, R.
Fonseca, M. V.
Sillanpää, A.
Ungerechts, H.
Panwar, N.
Orito, R.
Prada Moroni, P. G.
Bernardini, E.
Herrero, A.
Jorstad, S.
Blinov, D. A.
Bozhilov, V.
Mundell, C.
Nishijima, K.
Domínguez, A.
Paneque, D.
Babic, A.
Stamatescu, V.
Toyama, T.
Lombardi, S.
Vercellone, S.
Contreras, J. L.
Eisenacher, D.
Menzel, U.
Buson, S.
Covino, S.
Max-Moerbeck, W.
Da Vela, P.
Colin, P.
Rodriguez Garcia, J.
Idec, W.
Herrera, J.
Palatiello, M.
Paiano, S.
Paoletti, R.
Persic, M.
Richards, J. L.
Preziuso, S.
Scalzotto, V.
Giroletti, M.
Einecke, S.
Zandanel, F.
Troitsky, I. S.
Doro, M.
Lucarelli, F.
D’Ammando, F.
Munar-Adrover, P.
Sobczynska, D.
Stawarz, Łukasz
González Muñoz, A.
Carmona, E.
Hose, J.
Miranda, J. M.
Gómez, J. L.
Teshima, M.
Tescaro, D.
Pavlova, Yu. V.
Rhode, W.
Kodani, K.
Rügamer, S.
Agudo, I.
Aller, H. D.
Nakajima, D.
De Lotto, B.
Aleksić, J.
Carreto Fidalgo, D.
Zensus, J. A.
Mankuzhiyil, N.
Schweizer, T.
García López, R. J.
Rico, J.
Larionova, E. G.
Lelas, D.
Sandrinelli, A.
Pittori, C.
Kopatskaya, E. N.
Kushida, J.
Elsaesser, D.
Vogler, P.
Stamerra, A.
Lorenz, E.
Farina, E.
Strzys, M.
Takalo, L.
Steele, I.
Hildebrand, D.
Casadio, C.
De Caneva, G.
Sun, S.
Thaele, J.
Prandini, E.
Angelakis, E.
Saggion, A.
Paredes, J. M.
Frantzen, K.
Gozzini, S. R.
Hadasch, D.
Garczarczyk, M.
Lozano, I.
Acosta-Pulido, J. A.
Spanier, F.
Terzić, T.
Snidaric, I.
Lin, H. C.
Puljak, I.
Moralejo, A.
Mannheim, K.
Konno, Y.
Metodieva, I.
Tavecchio, F.
Nowak, N.
Saito, K.
Prada, F.
De Angelis, A.
Kurtanidze, O. M.
Larionova, L. V.
Sievers, A.
Martínez, M.
Garrido Terrats, D.
Niedzwiecki, A.
Colombo, E.
Antonelli, L. A.
Lindfors, E.
Storz, J.
Larionov, V. M.
Mariotti, M.
Krichbaum, T. P.
Maraschi, L.
López-Coto, R.
Blanch, O.
Cortina, J.
Meucci, M.
Becerra, González J.
Tibolla, O.
Mokrushina, A. A.
Nikolashvili, M. G.
Kubo, H.
Opis:: Aims. Amongst more than fifty blazars detected in very high energy (VHE, E> 100 GeV) γ rays, only three belong to the subclass of flat spectrum radio quasars (FSRQs). The detection of FSRQs in the VHE range is challenging, mainly because of their soft spectra in the GeV-TeV regime. MAGIC observed PKS 1510−089 (z = 0.36) starting 2012 February 3 until April 3 during a high activity state in the high energy (HE, E> 100 MeV) $\gamma$-ray band observed by AGILE and Fermi. MAGIC observations result in the detection of a source with significance of 6.0 standard deviations (σ). We study the multi-frequency behaviour of the source at the epoch of MAGIC observation, collecting quasi-simultaneous data at radio and optical (GASP-WEBT and F-Gamma collaborations, REM, Steward, Perkins, Liverpool, OVRO, and VLBA telescopes), X-ray (Swift satellite), and HE $\gamma$-ray frequencies. Methods. We study the VHE $\gamma$-ray emission, together with the multi-frequency light curves, 43 GHz radio maps, and spectral energy distribution (SED) of the source. The quasi-simultaneous multi-frequency SED from the millimetre radio band to VHE γ rays is modelled with a one-zone inverse Compton model. We study two different origins of the seed photons for the inverse Compton scattering, namely the infrared torus and a slow sheath surrounding the jet around the Very Long Baseline Array (VLBA) core. Results. We find that the VHE $\gamma$-ray emission detected from PKS 1510−089 in 2012 February-April agrees with the previous VHE observations of the source from 2009 March-April. We find no statistically significant variability during the MAGIC observations on daily, weekly, or monthly time scales, while the other two known VHE FSRQs (3C 279 and PKS 1222+216) have shown daily scale to sub-hour variability. The $\gamma$-ray SED combining AGILE, Fermi and MAGIC data joins smoothly and shows no hint of a break. The multi-frequency light curves suggest a common origin for the millimetre radio and HE $\gamma$-ray emission, and the HE $\gamma$-ray flaring starts when the new component is ejected from the 43 GHz VLBA core and the studied SED models fit the data well. However, the fast HE $\gamma$-ray variability requires that within the modelled large emitting region, more compact regions must exist. We suggest that these observed signatures would be most naturally explained by a turbulent plasma flowing at a relativistic speed down the jet and crossing a standing conical shock.
Dostawca treści:: Repozytorium Uniwersytetu Jagiellońskiego

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Skocz do pozycji: 3.

Tytuł:: Multifrequency studies of the peculiar quasar 4C +21.35 during the 2010 flaring activity
Autorzy:: Treves, A.
Wood, D. L.
Gurwell, M. A.
Stamatescu, V.
Murgia, S.
Maneva, G.
Dermer, C. D.
Saggion, A.
Porter, T. A.
Lister, M. L.
Horan, D.
Mayer, M.
Carreto Fidalgo, D.
Bangale, P.
Vasileiou, V.
Hadasch, D.
Brigida, M.
Antoranz, P.
Nikolashvili, M. G.
Gozzini, S. R.
Ribó, M.
Giavitto, G.
Gehrels, N.
Morselli, A.
Prandini, E.
Homan, D. C.
Thayer, J. B.
Vitale, V.
Krause, J.
Preziuso, S.
Chekhtman, A.
Chiang, J.
Knödlseder, J.
Rainò, S.
Cecchi, C.
Miranda, J. M.
Ferenc, D.
Bonnoli, G.
Bonamente, E.
Kushida, J.
Usher, T. L.
Sanchez, D. A.
Colin, P.
Takahashi, T.
Lozano, I.
Ciprini, S.
Sun, S.
Efimova, N. V.
Finke, J.
López-Coto, R.
Orienti, M.
Michelson, P. F.
Focke, W. B.
Mariotti, M.
Dominis Prester, D.
Reinthal, R.
Guiriec, S.
Meucci, M.
Partini, S.
Iafrate, G.
Jordan, B.
Frantzen, K.
Mirzoyan, R.
Bednarek, W.
Favuzzi, C.
Blanch, O.
Reimer, O.
Fruck, C.
Moskalenko, I. V.
Tosti, G.
Storz, J.
Conrad, J.
Larsson, S.
Paredes-Fortuny, X.
Shore, S. N.
Caraveo, P. A.
Bretz, T.
Fukazawa, Y.
Dazzi, F.
Lindfors, E.
Schweizer, T.
Godfrey, G.
Stamerra, A.
Mannheim, K.
Hayashida, M.
Orito, R.
Terzić, T.
Carosi, A.
Blinov, D. A.
Overkemping, A.
Mazziotta, M. N.
Berger, K.
Persic, M.
Babic, A.
Terrats, D. Garrido
Caneva, G. De
Perkins, J. S.
Sillanpää, A.
Scapin, V.
Teshima, M.
Giordano, F.
D'Ammando, F.
Johnson, A. S.
Stawarz, Łukasz
Kadenius, V.
Hose, J.
López-Oramas, A.
Lorenz, E.
Drell, P. S.
Mizuno, T.
Troja, E.
Gasparrini, D.
Reimer, A.
Kovalev, Y. Y.
Hewitt, J. W.
Spinelli, P.
Garczarczyk, M.
Carmona, E.
Fusco, P.
Ajello, M.
Franckowiak, A.
Mazin, D.
Buehler, R.
Giroletti, M.
Kuss, M.
Surić, T.
Takami, H.
Larionov, V. M.
Sgrò, C.
Giglietto, N.
De Angelis, A.
Niedzwiecki, A.
Bellazzini, R.
Menzel, U.
Elsaesser, D.
Ansoldi, S.
Tibolla, O.
Toyama, T.
Paiano, S.
Piron, F.
Torres, D. F.
Spandre, G.
Donato, D.
Sitarek, J.
Snidaric, I.
Font, L.
Wagner, R. M.
Aller, M. F.
Ros, E.
Tornikoski, M.
Cavazzuti, E.
Pivato, G.
Rügamer, S.
Contreras, J. L.
Ohsugi, T.
Werner, M.
Godinović, N.
Herrero, A.
Cortina, J.
Domínguez, A.
Martínez, M.
Pesce-Rollins, M.
Rico, J.
Satalecka, K.
Nilsson, K.
Doert, M.
Vianello, G.
Bonnefoy, S.
Kubo, H.
Vela, P. Da
Lombardi, S.
Sobczynska, D.
Prada, F.
Thaele, J.
González, J. Becerra
Tescaro, D.
Antolini, E.
Marcote, B.
López, R. J. García
Einecke, S.
Kurtanidze, O. M.
Grenier, I. A.
Thayer, J. G.
Almeida, U. Barres de
Cohen-Tanugi, J.
Saito, K.
Lubrano, P.
Lelas, D.
Djorgovski, S. G.
Cutini, S.
Puljak, I.
Schulz, A.
Borracci, F.
Allafort, A.
Kodani, K.
Munar-Adrover, P.
Lähteenmäki, A.
Makariev, M.
Barbiellini, G.
Nakajima, D.
Temnikov, P.
Monzani, M. E.
Gargano, F.
Razzano, M.
Zandanel, F.
Moroni, P. G. Prada
Aleksić, J.
Winer, B. L.
Eisenacher, D.
Idec, W.
Scalzotto, V.
Vandenbroucke, J.
Wood, K. S.
Caliandro, G. A.
Lewandowska, N.
Nishijima, K.
Claus, R.
Tavecchio, F.
Steinbring, T.
Angelakis, E.
Loparco, F.
Covino, S.
Tinivella, M.
Moralejo, A.
Drake, A. J.
Orlando, E.
Bernardini, E.
Bregeon, J.
Silva, E. do Couto e
Fonseca, M. V.
Sigua, L. A.
Ackermann, M.
Mendez, C. Delgado
Savolainen, T.
Buson, S.
Takahashi, H.
Bissaldi, E.
Konno, Y.
Gaug, M.
Lovellette, M. N.
Mallot, K.
Chiaro, G.
Kellermann, H.
Palatiello, M.
Garcia, J. Rodriguez
Knoetig, M. L.
Hughes, R. E.
Nemmen, R.
Chaves, R. C. G.
Lotto, B. De
Mankuzhiyil, N.
Bock, R. K.
Nieppola, E.
Cameron, R. A.
Thompson, D. J.
Schultz, C.
Zanin, R.
Lande, J.
Colombo, E.
McEnery, J. E.
Dorner, D.
Paredes, J. M.
Muñoz, A. González
Antonelli, L. A.
Doro, M.
Hildebrand, D.
Barbera, A. La
Bastieri, D.
Maraschi, L.
Takalo, L.
Vogler, P.
Salvati, M.
Latronico, L.
Longo, F.
Biland, A.
Bruel, P.
de Palma, F.
López, M.
Paneque, D.
Saito, T.
Spanier, F.
Nowak, N.
Rhode, W.
Kopatskaya, E. N.
Hrupec, D.
Barrio, J. A.
Farina, E.
Paoletti, R.
Siskind, E. J.
Nuss, E.
Opis:: The discovery of rapidly variable Very High Energy (VHE; E > 100 GeV) gamma-ray emission from 4C +21.35 (PKS 1222+216) by MAGIC on 2010 June 17, triggered by the high activity detected by the Fermi Large Area Telescope (LAT) in high energy (HE; E > 100 MeV) gamma-rays, poses intriguing questions on the location of the gamma-ray emitting region in this flat spectrum radio quasar. We present multifrequency data of 4C +21.35 collected from centimeter to VHE during 2010 to investigate the properties of this source and discuss a possible emission model. The first hint of detection at VHE was observed by MAGIC on 2010 May 3, soon after a gamma-ray flare detected by Fermi-LAT that peaked on April 29. The same emission mechanism may therefore be responsible for both the HE and VHE emission during the 2010 flaring episodes. Two optical peaks were detected on 2010 April 20 and June 30, close in time but not simultaneous with the two gamma-ray peaks, while no clear connection was observed between the X-ray and gamma-ray emission. An increasing flux density was observed in radio and mm bands from the beginning of 2009, in accordance with the increasing gamma-ray activity observed by Fermi-LAT, and peaking on 2011 January 27 in the mm regime (230 GHz). We model the spectral energy distributions (SEDs) of 4C +21.35 for the two periods of the VHE detection and a quiescent state, using a one-zone model with the emission coming from a very compact region outside the broad line region. The three SEDs can be fit with a combination of synchrotron self-Compton and external Compton emission of seed photons from a dust torus, changing only the electron distribution parameters between the epochs. The fit of the optical/UV part of the spectrum for 2010 April 29 seems to favor an inner disk radius of < six gravitational radii, as one would expect from a prograde-rotating Kerr black hole.
Dostawca treści:: Repozytorium Uniwersytetu Jagiellońskiego

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Skocz do pozycji: 4.

Tytuł:: Artificial intelligence for direct-to-physician reporting of ambulatory electrocardiography
Autorzy:: Meyre, P.B.
Rahkovich, M.
Miracle Blanco, A.
Benezet-Mazuecos, J.
Lozano, A.
Diederichsen, S.Z.
Shaked, E.
Fedorowski, A.
Linz, D.
Lewinter, C.
Benz, A.P.
Ljungström, E.
Zadrozniak, P.
Krisai, P.
Manninger, M.
Bennett, R.
Platonov, P.
Healey, J.S.
Glazer, E.
Stavrakis, S.
Jakaite, R.
Shen, C.
Brandes, A.
Rienstra, M.
Svennberg, E.
Marincheva, G.
Laish-Farkash, A.
Kogan, Y.
Juknevicius, V.
Engström, G.
Bisson, J.
Haugan, K.
Persson, A.
Vreeswijk, N.L.
Grotek-Cuprjak, A.
Marx, J. A.
Radoslovich, G.
Johnson, L.S.
Jamal, S.
Måneheim, A.
Hammarlund, P.
Matusik, Paweł
Jasina, G.
Glotzer, T.
Zafeiropoulos, S.
Mustafina, I.
Ruwald, M.H.
Oraii, A.
Węcławski, J.
Andrade, J.G.
Bacevicius, J.
Blum, S.
Wodaje, T.
Spittler, R.
Bhavnani, S.
McIntyre, W.F.
Iakobishvili, Z.
Dostawca treści:: Repozytorium Uniwersytetu Jagiellońskiego

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Skocz do pozycji: 5.

Tytuł:: BCG vaccination in patients with severe combined immunodeficiency: complications, risks, and
Autorzy:: Marciano, Beatriz E.
Espinosa-Padilla, Sara E.
Hernandez-Nieto, Leticia
Huang, Chiung-Yu
Kowalczyk, Danuta
Fleishe, Thomas A.
Yildiran, Alias
Cipe, Funda
Nuñez-Nuñez, M. Enriqueta
Neven, Bénédicte
Ohtsuka, Yoshitoshi
Ariga, Tadashi
Carvalho, Beatriz Costa
Gennery, Andrew
Esteves, Isabel
Morio, Tomohiro
Yamada, Masafumi
Roxo, Persio
Rezaei, Nima
Bezrodnik, Liliana
Slatte, Mary A.
Nademi, Zohreh
Sevciovic Grumach, Anete
Lau, Yu-Lung
Shcherbina, Anna
Reda, Shereen M.
Nishikomori, Ryuta
Ikinciogullari, Aydan
Elfeky, Reem A.
Listello, Viviana
Szaflarska, Anna
Joshi, Gyan
Toshio, Heike
Pereira, Mar ía I.
Thon, Vojtech
Torres-Lozano, Carlos
Rosenzweig, Sergio D.
Gόmez Raccio, Andrea C.
Al-Tamemi, Salem
Formankova, Renata
Porras, Oscar
Pinto, Jorge A.
Franco, Jose L.
Al-Herz, Waleed
Kiliç, Şebnem
Liberatore, Diana
Orellana, Julio C.
Marques, Jose Gonçalo
Dogu, Figen
Gala, Nermeen
Davies, Graham
Espinosa-Rosales, Francisco
Allwood, Zoe
Opis:: Background: Severe combined immunodeficiency (SCID) is a syndrome characterized by profound T-cell deficiency. BCG vaccine is contraindicated in patients with SCID. Because most countries encourage BCG vaccination at birth, a high percentage of patients with SCID are vaccinated before their immune defect is detected. Objectives: We sought to describe the complications and risks associated with BCG vaccination in patients with SCID. Methods: An extensive standardized questionnaire evaluating complications, therapeutics, and outcomes regarding BCG vaccination in patients given a diagnosis of SCID was widely distributed. Summary statistics and association analysis was performed. Results: Data on 349 BCG-vaccinated patients with SCID from 28 centers in 17 countries were analyzed. Fifty-one percent of the patients had BCG-associated complications, 34% disseminated and 17% localized (a 33,000- and 400-fold increase, respectively, over the general population). Patients receiving early vaccination (<_1 month) showed an increased prevalence of complications (P 5 .006) and death caused by BCG-associated complications (P < .0001). The odds of experiencing complications among patients with T-cell numbers of 250/mL or less at diagnosis was 2.1 times higher (95% CI, 1.4-3.4 times higher; P 5 .001) than among those with T-cell numbers of greater than 250/mL. BCG-associated complications were reported in 2 of 78 patients who received antimycobacterial therapy while asymptomatic, and no deaths caused by BCG-associated complications occurred in this group. In contrast, 46 BCG-associated deaths were reported among 160 patients treated with antimycobacterial therapy for a symptomatic BCG infection (P < .0001). Conclusions: BCG vaccine has a very high rate of complications in patients with SCID, which increase morbidity and mortality rates. Until safer and more efficient antituberculosis vaccines become available, delay in BCG vaccination should be considered to protect highly vulnerable populations from preventable complications. (
Dostawca treści:: Repozytorium Uniwersytetu Jagiellońskiego