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Wyświetlanie 1-10 z 15
Tytuł:
The efficacy of cognitive rehabilitation with RehaCom programme in schizophrenia patients. The role of selected genetic polymorphisms in successful cognitive rehabilitation
Autorzy:
Mak, M.
Samochowiec, J.
Tybura, P.
Bienkowski, P.
Karakiewicz, B.
Zaremba-Pechmann, L.
Mroczek, B.
Wydawca:
Instytut Medycyny Wsi
Powiązania:
https://bibliotekanauki.pl/articles/51211.pdf  Link otwiera się w nowym oknie
Opis:
Introduction. Schizophrenic patients present cognitive dysfunctions which are regarded to be one of endophenotypical markers predisposing to schizophrenia. Currently, schizophrenia can be treated as a neurodegenerative and neurodeveloping disease with genetic background. Objective. Assessment of the possible positive effect of neuropsychological rehabilitation in schizophrenia, in patients presenting cognitive dysfunctions. An additional aim was to verify the hypothesis that some genetic polymorphisms can be a prognostic factor for success in neuropsychological rehabilitation. Material and methods. 41 participants and 40 control subjects were randomly selected. Both groups had the diagnosis of paranoid schizophrenia. Cognitive functions were checked with the Wisconsin Card Sorting Test, Trail Making Test, and Stroop Test at the beginning and end of the experiment. In the research group, each patient trained with the rehabilitation programme RehaCom, whereas the control group did not receive such training. Genes COMT rs4680 and BDNF rs6265 were analysed in the genetic part of study. Results. RehaCom procedures appear to be useful in the neuropsychological rehabilitation of cognitive dysfunctions in patients diagnosed with schizophrenia. The research group showed a moderate improvement in the training programmes. Analysis of parameters obtained in the neuropsychological tests showed a slight improvement in both groups. At the present time, analysis of the polymorphisms of genes cannot be treated as a prognostic factor for the success of neuropsychological rehabilitation because statistical analyses showed few dependences with little statistical significance. Conclusions. Cognitive rehabilitation produces moderate improvement in cognitive functioning.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Production of zinc-enriched biomass of Saccharomyces cerevisiae
Produkcja wzbogaconej cynkiem biomasy Saccharomyces cerevisiae
Autorzy:
Azad, S.K.
Shariatmadari, F.
Torshizi, M.A.K.
Wydawca:
Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
Powiązania:
https://bibliotekanauki.pl/articles/13829.pdf  Link otwiera się w nowym oknie
Opis:
Zinc accumulation and the growth of Saccharomyces cerevisiae were investigated in a culture with zinc sulfate-supplemented medium. The cultivations were performed on Sabouraud dextrose broth medium in aerobic conditions, without the addition of zinc (control culture) and with the addition of zinc sulfate (5, 10, 15, 30 and 60 mg ZnSO l -1 medium) at 28 ° C for 72 hours. The results showed similar trends of yeast growth rates at 24, 48, and 72-hour interval, with concentrations above 10 mg l -1 ZnSO in the nutritional medium significantly decreasing the yeast growth rate and the biomass yield ( P <0.05). Substantial differences between the initial ZnSO concentrations in the growth medium were demonstrated in the overall adsorption of Zn ions (Zn 2+ ) in yeast cells by a colorimetric assay ( P <0.05). Similarly, the content of total accumulated zinc, as well as the fractions of Zn present in cells depended mainly on the zinc concentration in the medium, as the total Zn accumulation and organically bound Zn fractions were increased by elevating the ZnSO supplementation in the culture medium up to 30 mg l -1 , but gradually reduced by any further addition of ZnSO determined by an ICP-MASS assay ( P <0.05). In the presence of 30 mg l -1 ZnSO , the Zn content in the biomass increased by 24-fold, to 4132.34 m g g -1 in comparison to 171.9 m g g -1 achieved in the basal medium. Thus, the ability of S. cerevisiae to accumulate zinc can be used for production of a zinc-rich ingredient for functional food products.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Towards the propagation of a critically endangered tree species Anisoptera scaphula
Autorzy:
Hossain, M.A.
Ferdous, J.
Rahman, M.A.
Azad, M.A.K.
Shukor, N.A.A.
Tematy:
propagation
endangered species
tree
Anisoptera scaphula
Dipterocarpaceae
seed
sowing position
germination percentage
rooting ability
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Wydawca:
Polska Akademia Nauk. Instytut Dendrologii PAN
Powiązania:
https://bibliotekanauki.pl/articles/41522.pdf  Link otwiera się w nowym oknie
Opis:
Anisoptera scaphula (Roxb.) Kurz, the tallest tree species in Bangladesh, is critically endangered worldwide due to its poor natural regeneration. This study describes the appropriate regeneration technique for A. scaphula through seed germination and clonal propagation by stem cutting. The fastest and highest germination percentage (65) was observed in dewinged seeds sown inverted orientation with half buried position (T10) followed by dewinged seeds (62.5%) sown horizontally in full buried (T7) and delayed germination with lowest percentage (15) was in control (T0). Optimum initial growth was also shown when seedlings were developed from the seeds under T7. Both winged and dewinged seeds sown vertically in full buried or half buried position produced curved seedlings. However, dewinged seeds sown in horizontal or inverted (winged side down) position produced otherwise i.e., straight seedlings. The highest rooting percentages (63%) and maximum number of root (4.8) per cutting were obtained when one node cuttings treated with 0.8% IBA solution followed by 0.4% IBA in turn affecting for better survival and growth of rooted cuttings in the nursery conditions.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Probing the structure-function relationship of hemoglobin in living human red blood cells
Autorzy:
Bokamper, Matthew J.
Marzec, Katarzyna M.
Mak, Piotr J.
Dybaś, Jakub
Opis:
Hemoglobin (Hb) is a key component of respiratory system and as such plays important role in human physiology. The studies of Hb's structure and functions are usually performed on cell-free protein; however, it has been shown that there are functionally relevant differences between isolated Hb and Hb present inside red blood cells (RBCs). It is clear that new experimental approaches are needed to understand the origin of these differences and to gain insight into the structure-function relationship of Hb within intact living cells. In this work we present a novel application of Resonance Raman spectroscopy to study heme active site of different forms of human Hb within living RBCs using laser excitation lines in resonance with their Soret absorption bands. These studies revealed that there are no significant changes in the disposition of the Fe-O-O fragment or the Fe-NHis linkage for Hb molecules enclosed in RBCs and these in free isolated states. However, some changes in the orientation of the heme vinyl groups were observed which might account for the differences in the protein activity and ligand affinity. This work highlights importance of protein-based studies and presents a new opportunity to translate these results to physiological cell systems.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
Tytuł:
Three- versus Two-Dimensional Electron Gas Injection in Resonant Tunnelling
Autorzy:
Figielski, T.
Wosiński, T.
Mąkοsa, A.
Kaniewska, M.
Regiński, K.
Tematy:
73.40.Gk
85.30.Mn
Pokaż więcej
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Powiązania:
https://bibliotekanauki.pl/articles/1933735.pdf  Link otwiera się w nowym oknie
Opis:
A small "precursor" of resonance is observed before the main resonance peak in the current-voltage characteristic of double-barrier resonant-tunnelling devices. The competition between the precursor and main-peak current is examined within the temperature range 4.2-400 K. The precursor is interpreted as 3DEG contribution to the resonant tunnelling dominated by a 2DEG injection from a triangular well formed under bias in the emitter spacer layer.
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-10 z 15

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