Autor: Paul, James - Prolib Integro

Skocz do pozycji: 1.

Tytuł:: Applicationes Mathematicae T.15 (1976-1977)
Comparison of fixed precision estimation schemes in Bernoulli trials
Zastosowania Matematyki T.15 (1976-1977)
Porównywanie estymacji o ustalonej precyzji w próbach Bernoulliego
Autorzy:: Mikulski, Piotr Witold
Smith, Paul James
Współwytwórcy:: Polska Akademia Nauk. Instytut Matematyczny.
Wydawca:: Państwowe Wydawnictwo Naukowe
Opis:: Abstract in Polish
Streszczenie w jęz. polskim
Od t.8 (1965) tyt. równol. : Applicationes Mathematicae
25 cm
Dostawca treści:: RCIN - Repozytorium Cyfrowe Instytutów Naukowych

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Skocz do pozycji: 2.

Artykuł

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Skocz do pozycji: 3.

Tytuł:: Evaluation maps, restriction maps, and compactness
Autorzy:: Bator, Elizabeth
Lewis, Paul
Ochoa, James
Wydawca:: Polska Akademia Nauk. Instytut Matematyczny PAN
Powiązania:: https://bibliotekanauki.pl/articles/966089.pdf Link otwiera się w nowym oknie
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Serum fluoride levels in ambulance staff after commencement of methoxyflurane administration compared to meta-analysis results for the general public
Autorzy:: Allison, Serah J.
Docherty, Paul D.
Pons, Dirk
Chase, James G.
Tematy:: meta-analysis
prospective studies
fluorides
ambulances
fluoride poisoning
methoxyflurane; Pokaż więcej
Wydawca:: Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Powiązania:: https://bibliotekanauki.pl/articles/2093863.pdf Link otwiera się w nowym oknie
Opis:: ObjectivesAmbulance officers administering methoxyflurane as an inhalational analgesic may be exposed to trace vapor. Fluoride is a methoxyflurane metabolite, and has been associated with acute renal failure in anesthesia patients and skeletal fluorosis with chronic elevated serum levels from other sources. However, there has been no direct measurement of serum fluoride in occupationally exposed ambulance officers. Thus, this study directly measures serum fluoride over a prolonged period in order to determine renal toxic and skeletal fluorosis risk to ambulance officers who are administering methoxyflurane.Material and MethodsSerum inorganic fluoride concentrations were measured in a prospective observational study of 12 emergency medical technicians (EMTs). The study took 7 serum fluoride measurements over 24 months. A meta-analysis of healthy adult serum fluoride ranges was also conducted.ResultsThe typical healthy adult serum fluoride range was determined to be 0.21–2.11 μmol/l (p < 0.001). The EMTs’ baseline median (IQR) serum fluoride concentrations were 0.4 μmol/l (0.2; 1.0) with maximum 1.6 μmol/l. The EMTs’ overall median serum fluoride was 0.4 μmol/l (0.2; 1.3) with maximum 4.0 μmol/l, usually within healthy reference ranges. All results were ≤10% of the suggested single-dose renal toxic threshold. One result was above a threshold for skeletal fluorosis. The highest measured serum fluoride was 24% of the lowest level associated with radiologic evidence of fluorosis. There was no evidence overall of increasing serum fluoride levels.ConclusionsThere was no evidence that EMTs’ exposure to methoxyflurane resulted in sustained increased serum fluoride. These results imply EMTs’ occupational safety from acute renal toxicity when activated carbon filtration is used on patient exhalation. However, 1 serum fluoride result above a skeletal fluorosis threshold suggests that the risk of mild skeletal fluorosis cannot be excluded.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 5.

Tytuł:: The Messenger of Mathematics
Sur la loi des grands nombres de poisson
Autorzy:: Mansion, Paul (1844–1919)
Współwytwórcy:: Glaisher, James Whitbread Lee (1848–1928). Red.
Wydawca:: Macmillan and Co.
Powiązania:: The Messenger of Mathematics
Opis:: 22 cm
Opis na podst. : vol. 19 (1889/1890) oraz British Union Catalogue - COPAC
Description based on: vol. 19 (1889/1890) oraz British Union Catalogue - COPAC
Dostawca treści:: RCIN - Repozytorium Cyfrowe Instytutów Naukowych

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Skocz do pozycji: 6.

Tytuł:: Prohibitins and Ras2 protein cooperate in the maintenance of mitochondrial function during yeast aging.
Autorzy:: Kirchman, Paul
Miceli, Michael
West, Roger
Jiang, James
Kim, Sangkyu
Jazwinski, S
Tematy:: ROS
retrograde response
Saccharomyces cerevisiae
longevity
mitochondrial biogenesis; Pokaż więcej
Wydawca:: Polskie Towarzystwo Biochemiczne
Powiązania:: https://bibliotekanauki.pl/articles/1043375.pdf Link otwiera się w nowym oknie
Opis:: The yeast Saccharomyces cerevisiae has a finite replicative life span. Yeasts possess two prohibitins, Phb1p and Phb2p, in similarity to mammalian cells. These proteins are located in the inner mitochondrial membrane, where they are involved in the processing of newly-synthesized membrane proteins. We demonstrate that the elimination of one or both of the prohibitin genes in yeast markedly diminished the replicative life span of cells that lack fully-functional mitochondria, while having no effect on cells with functioning mitochondria. This deleterious effect was suppressed by the deletion of the RAS2 gene. The expression of PHB1 and PHB2 declined gradually up to 5-fold during the life span. Cells in which PHB1 was deleted in conjunction with the absence of a mitochondrial genome displayed remarkable changes in mitochondrial morphology, distribution, and inheritance. This loss of mitochondrial integrity was not seen in cells devoid of PHB1 but possessing an intact mitochondrial genome. In a subset of the cells, the changes in mitochondrial integrity were associated with increased production of reactive oxygen species, which co-localized with the altered mitochondria. The mitochondrial deficits described above were all suppressed by deletion of RAS2. Our data, together with published information, are interpreted to provide a unified view of the role of the prohibitins in yeast aging. This model posits that the key initiating event is a decline in mitochondrial function, which leads to progressive oxidative damage that is exacerbated in the absence of the prohibitins. This aggravation of the initial damage is ameliorated by the suppression of the production of mitochondrial proteins in the absence of Ras2p signaling of mitochondrial biogenesis.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 7.

Tytuł:: Bulletin de lʾAcadémie Polonaise. Série des Sciences Mathématiques
Série des Sciences Mathématiques
Operators on spaces of continuous functions
Autorzy:: Brooks, James K.
Współwytwórcy:: Polska Akademia Nauk.
Lewis, Paul W.
Państwowe Wydawnictwo Naukowe (1951–1992)
Wydawca:: Państwowe Wydawnictwo Naukowe
Opis:: 23 cm
Dostawca treści:: RCIN - Repozytorium Cyfrowe Instytutów Naukowych