- Tytuł:
- Genetic markers for the detection of quantitative trait loci with special consideration of body weight and fat
- Autorzy:
-
Kopplow, K.
Das, P.
Brockmann, G. A.
Renne, U. - Powiązania:
- Acta Theriologica
- Opis:
- Mouse chromosome 11 was analyzed for the presence of quantitative trait loci (QTL) affecting body weight and fatness. Significant differences in allele frequencies (p<10-2) between two growth differentiated mouse lines DU6 and DUKs were proven at the marker loci D11Mit120, D11Mit125, and D11Mit126. In families which were derived from crosses between DU6 and DUKs cosegregation of genetic marker alleles and individual trait performance was analyzed. Variance analysis proved highly significant phenotypic differences between genotype groups (p<10-5), localized in one family in the chromosomal part between D11Mit236 and D11Mit126. These results were confirmed in independent families of parallel crosses. The detected chromosomal region affected both, body weight and fatness.
- Dostawca treści:
- RCIN - Repozytorium Cyfrowe Instytutów Naukowych
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