- Tytuł:
- Minimal information for studies of extracellular vesicles (MISEV2023) : from basic to advanced approaches
- Autorzy:
-
Harris, Adrian L.
Goberdhan, Deborah C. I.
Buzas, Edit I.
Maddox, Adam L.
Saftics, Andras
Blenkiron, Cherie
Ochiya, Takahiro
Rojalin, Tatu
Newman, Lauren A.
van Herwijnen, Martijn J. C.
Bussolati, Benedetta
Brucale, Marco
Zimmerman, Alan J.
Wauben, Marca H. M.
Wehman, Ann M.
Lenassi, Metka
Lennon, Kathleen M.
Möller, Andreas
Sahoo, Susmita
Sandau, Ursula S.
Swift, Simon
Ter‐Ovanesyan, Dmitry
Jovanovic‐Talisman, Tijana
Mizenko, Rachel R.
O'Driscoll, Lorraine
Welsh, Joshua A.
Cai, Houjian
Shekari, Faezeh
Burger, Dylan
Di Vizio, Dolores
Useckaite, Zivile
Witwer, Kenneth W.
Lim, Sai Kiang
Théry, Clotilde
Rohde, Eva
Abuelreich, Sarah
Fu, Qing‐Ling
Cocucci, Emanuele
Williams, Sarah
Zuba-Surma, Ewa
Tosar, Juan P.
Ivanov, Alexander R.
Falcon‐Perez, Juan M.
Carney, Randy P.
Erdbrügger, Uta
Hendrix, An
Ku'ulei‐Lyn Faustino, Vroniqa
Kyburz, Diego
Hill, Andrew F.
Hanser, Edveena
Nieuwland, Rienk
Saugstad, Julie A.
Bobis-Wozowicz, Sylwia
Zendrini, Andrea
Ridolfi, Andrea
Valle, Francesco
Driedonks, Tom A. P.
Stępień, Ewa
Lässer, Cecilia
Mahoney, Mỹ G.
Martens‐Uzunova, Elena S.
Bridges, Esther M.
Rowland, Andrew
Crescitelli, Rossella
Zijlstra, Andries
Bergese, Paolo
Lötvall, Jan
Varga, Zoltan
Zheng, Lei
Mohanty, Sujata
Haughey, Norman J.
Bagabas, Reem
Kruh‐Garcia, Nicole A.
Karnas, Elżbieta
van der Pol, Edwin
Torrecilhas, Ana C. - Opis:
- Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of origin and change the functions and phenotypes of other cells. These features indicate strong biomarker and therapeutic potential and have generated broad interest, as evidenced by the steady year-on-year increase in the numbers of scientific publications about EVs. Important advances have been made in EV metrology and in understanding and applying EV biology. However, hurdles remain to realising the potential of EVs in domains ranging from basic biology to clinical applications due to challenges in EV nomenclature, separation from non-vesicular extracellular particles, characterisation and functional studies. To address the challenges and opportunities in this rapidly evolving field, the International Society for Extracellular Vesicles (ISEV) updates its ‘Minimal Information for Studies of Extracellular Vesicles’, which was first published in 2014 and then in 2018 as MISEV2014 and MISEV2018, respectively. The goal of the current document, MISEV2023, is to provide researchers with an updated snapshot of available approaches and their advantages and limitations for production, separation and characterisation of EVs from multiple sources, including cell culture, body fluids and solid tissues. In addition to presenting the latest state of the art in basic principles of EV research, this document also covers advanced techniques and approaches that are currently expanding the boundaries of the field. MISEV2023 also includes new sections on EV release and uptake and a brief discussion of in vivo approaches to study EVs. Compiling feedback from ISEV expert task forces and more than 1000 researchers, this document conveys the current state of EV research to facilitate robust scientific discoveries and move the field forward even more rapidly.
- Dostawca treści:
- Repozytorium Uniwersytetu Jagiellońskiego
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