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Wyszukujesz frazę "Sheridan, C." wg kryterium: Autor


Wyświetlanie 1-2 z 2
Tytuł:
Broadband multi-wavelength properties of M87 during the 2018 EHT campaign including a very high energy flaring episode
Autorzy:
Nickel, L.
Vos, J.
Errando, M.
Niinuma, K.
Maldera, S.
Saturni, F. G.
Satapathy, K.
Brissenden, R.
Impellizzeri, C. M. V.
Issaoun, S.
Kubo, H.
Roache, E.
Moriyama, K.
Berenji, B.
Georgiev, B.
Patel, N.
Lindfors, E.
Kaaret, P.
Foote, J.
Leone, F.
Ceribella, G.
Hadasch, D.
Johnson, M. D.
Hahn, A.
Kluźniak, W.
Negro, M.
Godinović, N.
Okumura, A.
Kim, D.-J.
Barres de Almeida, U.
Chan, C.-k.
Biland, A.
Moran, J. M.
Abhishek, A.
Green, D.
Silvestri, G.
de Naurois, M.
Weintroub, J.
Takahashi, M.
Wach, T.
Honma, M.
Mizuno, T.
Zech, A.
Eatough, R. P.
Stamerra, A.
Mereu, I.
Paredes, J. M.
Suson, D. J.
Lombardi, S.
Inoue, M.
Einecke, S.
Nigro, C.
Ryan, J. L.
Chang, D. O.
Nishijima, K.
Millard, M. J.
Jannuzi, B. T.
McGrath, C. E.
Ward-Thompson, D.
Kramer, M.
Roelofs, F.
Gradetzke, T.
Liu, X.
Santangelo, A.
Kettenis, M.
Brose, R.
Fukami, S.
Doro, M.
Hirota, T.
Matthews, L. D.
Ohm, S.
Fröse, S.
Chen, Y.
Liuzzo, E.
Marchili, N.
Ricarte, A.
Duerr, A.
Ravikularaman, S.
Sánchez-Conde, M.
Huang, Zhiqiu
Shao, L.
Font, L.
Lo, W.-P.
Chatterjee, S.
Grenier, I. A.
Antonelli, L. A.
Giordano, F.
Leitl, F.
Rani, B.
Di Pierro, F.
Colombo, E.
Neilsen, J.
Kosack, K.
Holch, T. L.
Navarro Fuentes, S.
Nanci, C.
Haggard, D.
Berge, D.
Wagner, S. J.
Kravchenko, E. V.
Tavecchio, F.
Ramakrishnan, V.
Li, G.
Tsirou, M.
Schloerb, F. P.
Rottmann, H.
Caraveo, P. A.
Boisson, C.
Miener, T.
Toma, K.
Holder, J.
Sgrò, C.
Bradascio, F.
Grau, R.
Bach, U.
Aguasca-Cabot, A.
Kasai, E.
Barrio, J. A.
Contreras, J. L.
Jiménez-Rosales, A.
Fraga-Encinas, R.
Savolainen, T.
Gargano, F.
Bonino, R.
Panny, S.
Arbet Engels, A.
Narayanan, G.
Cotter, G.
Kramer, J. A.
Mizuno, Y.
O’Brien, S.
Nilsson, K.
Mackey, J.
Bautista, A.
Berti, A.
de Bony de Lavergne, M.
Tanaka, T.
Brown, A.
Germani, S.
Cui, Y.-Z.
Benson, B. A.
Falcone, A. D.
Babić, A.
Cerasole, D.
Fariña, L.
Zhao, R.
Lang, R. G.
Özel, F.
Kim, J.
Vassiliev, V. V.
Lamastra, A.
Ball, D.
Chen, M.-T.
Johnson, M. N.
Humensky, T. B.
Ernenwein, J.-P.
Kushida, J.
Nakamura, M.
Prada Moroni, P. G.
Santander, M.
Dazzi, F.
Paoletti, R.
La Bella, N.
Sohn, B. W.
Fuentes, A.
Celic, J.
Terauchi, K.
Myserlis, I.
Stanway, J. S.
Bronzwaer, T.
Cho, I.
Torres, D. F.
Ro, H.
Barrett, J.
Elsaesser, D.
Blanch, O.
Wielgus, M.
Sitarek, J.
Djuvsland, J.
Sánchez-Portal, M.
Khatoon, R.
Funk, S.
Loparco, F.
Reville, B.
Majumdar, P.
Otero-Santos, J.
Chatterjee, K.
Natarajan, I.
Hinrichs, C. E.
Zhao, G.-Y.
Torne, P.
Gaug, M.
Omodei, N.
Castro-Tirado, A. J.
Baloković, M.
Cerruti, M.
Mondal, H. A.
Bruel, P.
Pensec, U.
Ohtani, Y.
lackburn, L.
Tiede, P.
Park, J.
Kramer, C.
Hesper, R.
Mus, A.
Davelaar, J.
Machado de Oliveira Fraga, B.
Pirola, G.
Liu, J.
Ford, N. M.
Ford, H. A.
Small, D.
Dihingia, I. K.
De Lotto, B.
Kumar, S.
Nagai, H.
Kerszberg, D.
Nievas Rosillo, M.
Tazaki, F.
Martí-Vidal, I.
Persic, M.
Saz Parkinson, P. M.
Gasbarra, C.
Splettstoesser, M.
Kobayashi, Y.
Tetarenko, A. J.
Leuschner, F.
Aschersleben, J.
Tutone, A.
Malyshev, D.
Schäfer, J.
De Laurentis, M.
Nikolić, L.
Yamaguchi, P.
Righi, C.
Suzuki, H.
Goswami, P.
Furniss, A.
Keating, G. K.
Prather, B.
Di Tria, R.
Wong, G. N.
Porth, O.
de Ona Wilhelmi, E.
Maneva, G.
Chen, Z.
Baczko, A.-K.
Mariotti, M.
Strzys, M.
Barbosa Martins, V.
Oh, J.
Zensus, J. A.
Krichbaum, T. P.
Wierzcholska, A.
Li, B.
Principe, G.
D’Elia, V.
Batzofin, R.
Sharma, A.
Gold, R.
Yadlapalli, N.
Longo, F.
Manganaro, M.
Bauböck, M.
Kleiner, T. K.
Lovellette, M. N.
Giesbrecht Paiva, J. G.
Kocherlakota, P.
Schmuckermaier, F.
Becherini, Y.
Boyce, H.
Mazziotta, M. N.
Fomalont, E.
Fukazawa, Y.
Martínez, M.
Lobanov, A. P.
Krennrich, F.
Suutarinen, S.
Conway, J. E.
Verna, G.
Bouman, K. L.
Lindqvist, M.
Farah, J.
Le Stum, S.
Xia, B.
Zhang, H.
Carretero-Castrillo, M.
Reis, I.
Herrera Llorente, J.
Menchiari, S.
Sun, H.
Takahashi, T.
Moscibrodzka, M.
Kuss, M.
Anantua, R.
Marx, R.
Psaltis, D.
Borowska, J.
Yan, H.
Morselli, A.
Ashkar, H.
Podobnik, F.
Valverde, J.
Trippe, S.
Lonsdale, C. J.
Zhao, S.-S.
Cavazzuti, E.
Mitchell, A.
Panter, M.
Salzmann, H.
Foschi, M.
Jeter, B.
Stawarz, Łukasz
Busetto, G.
Toscano, T.
Sheridan, C.
Gómez-Ruiz, A. I.
Hassan, T.
D’Amico, G.
Jorstad, S.
Li, Z.
Yuan, Y.-F.
Olivares, H.
PopStefanija, A.
Schonfeld, J.
Katarzyński, K.
van Eldik, C.
Yfantis, A.
López-Moya, M.
Mazin, D.
Carosi, R.
Cheong, W.-Y.
Wang, N.
Takeishi, R.
Domínguez, A.
Dominis Prester, D.
Artero, M.
García, R.
Sahakian, V.
Müller, C.
Streil, K.
López-Coto, R.
Hanlon, W.
Roshanineshat, A.
Aniello, T.
Vazquez Acosta, M.
Dexter, J.
Matsushita, S.
Njoh Ekoume, T.
Dinesh, A.
Jung-Richardt, I.
Tilanus, R. P. J.
Burelli, I.
Emami, R.
Shapopi, J. N. S.
Yu, W.
Dorner, D.
Jiménez Martínez, I.
Sciaccaluga, A.
Schüssler, F.
Vovk, I.
Sakai, N.
Arcaro, C.
Grolleron, G.
Lang, M. J.
Dempsey, J.
Heckmann, L.
Kertzman, M.
Washington, J. E.
Martí-Devesa, G.
Sánchez, S.
Ikeda, S.
Marrone, D. P.
Yuan, F.
Lisakov, M.
MacDonald, N. R.
Sol, H.
Di Lalla, N.
Molero González, M.
Blandford, R. D.
Mizuno, I.
Garczarczyk, M.
Musoke, G.
Holler, M.
Pesce, D. W.
Orlando, E.
Hays, E.
Cecil, R.
Algaba, J. C.
Pen, U.-L.
Lowitz, A. E.
Cristarella Orestano, P.
Hrupec, D.
Fromm, C. M.
Azulay, R.
Conroy, N. S.
Koch, P. M.
Alberdi, A.
Roy, A. L.
Pihet, M.
Moralejo, A.
Young, A.
Da Vela, P.
Batković, I.
Gu, M.
Markoff, S.
Fontaine, G.
Titus, M.
Kuo, C.-Y.
Michail, J.
Chen, A.
Wiik, K.
Neustroev, V.
Lico, R.
Montanari, A.
Sembroski, G. H.
Besenrieder, J.
Desvignes, G.
Lenain, J.-P.
Moulin, E.
Kofuji, Y.
Carosi, A.
Moriarty, P.
Miranda, J. M.
van Langevelde, H. J.
Abe, S.
van Rossum, D. R.
Böttcher, M.
Ruszczyk, C.
Covino, S.
Bower, G. C.
Ripperda, B.
Ong, R. A.
Priyadarshi, C.
Tucci, J. V.
Temnikov, P.
Meyer, M.
Blundell, R.
Koay, J. Y.
Di Venere, L.
Damascene Mbarubucyeye, J.
Moderski, R.
O’Brien, P.
Mannheim, K.
Jones, A. C.
Doeleman, S. S.
Cortina, J.
Turk, M.
Makariev, M.
Huang, C.-W. L.
Prandini, E.
Pohl, M.
Wu, Q.
Heumann, D.
Reynolds, P. T.
Freeman, W. T.
Raymond, A. W.
Franckowiak, A.
Truzzi, S.
Monzani, M. E.
Loinard, L.
Friberg, P.
Giliberti, M.
Mao, J.
Jormanainen, J.
James, D. J.
Molina, E.
Abhir, J.
Gentaz, O.
Okino, H.
Rao, R.
Ribeiro, D.
Crawford, T. M.
Gómez, J. L.
Chael, A.
Deane, R.
Lyard, E.
van Scherpenberg, J.
Sadeh, I.
Ciprini, S.
Maier, G.
Imazawa, R.
Mas-Aguilar, A.
Pita, S.
Liu, Z.
Ubach, S.
Donini, A.
Savchenko, S. S.
Dhruv, V.
Schmidt, K.
Cifuentes, A.
Kundu, A.
Palumbo, D. C. M.
Green, J. G.
Zacharias, M.
Lundy, M.
Sasada, M.
Niemiec, J.
Kawashima, T.
Bonnoli, G.
Acciari, V. A.
Filippos Paraschos, G.
Günther, P.
Will, M.
Glawion, D.
Cutini, S.
Peresano, M.
Feng, Q.
Chai, Y.
Traianou, E.
Hada, K.
Luashvili, A.
Ishio, K.
Sahakyan, N.
Quinn, J.
Paneque, D.
Kerby, S.
Kieda, D.
Saha, L.
Adams, C. B.
Glicenstein, J. F.
Gammie, C. F.
Acharyya, A.
Broguiere, D.
Wajima, K.
Lu, R.-S.
Sasaki, M.
Delfino, M.
Carlstrom, J. E.
Reimer, O.
Steppa, C.
Sosapanta Salas, L. D.
Lemière, A.
Bruno, B.
Bigongiari, C.
Marscher, A. P.
Giroletti, M.
Fortson, L.
Ros, E.
Cameron, R. A.
Ostrowski, Michał
Taylor, A. M.
Vecchi, M.
Lindahl, G.
Jung, T.
Koyama, S.
Casanova, S.
Baxter, J.
Schweizer, T.
Nowak, M. A.
Martínez-Chicharro, M.
Quirrenbach, A.
Foffano, L.
Witzel, G.
Britzen, S.
Fegan, S. J.
Ruiz, I.
Backes, M.
Bošnjak, Ž.
De Angelis, A.
Yamamoto, T.
Schutte, H. M.
Liu, K.
Miceli, D.
Menten, K. M.
Christian, P.
Zhong, W.
Campoy-Ordaz, A.
Terzić, T.
Ragan, K.
Joshi, A. V.
Giglietto, N.
D’Ammando, F.
Fattorini, A.
Walter, R.
Haerer, L.
Teshima, M.
Bandyopadhyay, B.
Bednarek, W.
Agudo, I.
Gurwell, M. A.
Ma, J.
Falcke, H.
de Menezes, R.
Shang, R.
Moghadam, M. O.
Bintley, D.
Zaharijas, G.
Medeiros, L.
Bulik, T.
Kino, M.
Komin, Nu.
Loporchio, S.
Nathanail, A.
Ruiz-Velasco, E.
Mirabal, N.
Lee, S.-S.
Trent, T.
Bangale, P.
Bernardini, E.
Bissaldi, E.
Noda, K.
Hughes, D. H.
Parsons, H.
Reimer, A.
Becerra González, J.
Gabici, S.
Kaur, A.
Żywucka, N.
Piétu, V.
Tajima, H.
Bronzini, E.
Ansoldi, S.
Kayanoki, T.
Lemoine-Goumard, M.
Sánchez-Argüelles, D.
Asano, K.
Siskind, E. J.
Vigorito, C. F.
Strom, D.
Mooney, C. L.
Viale, I.
Müller, H.
Nakamori, T.
Rico, J.
Karuppusamy, R.
Asada, K.
Chand, T.
Rygl, K. L. J.
Fusco, P.
Mukherjee, R.
Lorini, A.
Gliwny, P.
Spinelli, P.
Wagner, J.
Khélifi, B.
Oyama, T.
Ni, C.
Bellazzini, R.
Bouyahiaoui, M.
Jamrozy, Marek
Yonekura, Y.
Crew, G. B.
Devin, J.
Pueschel, E.
Younsi, Z.
Sawada-Satoh, S.
Jin, W.
Ventura, S.
Bartkoske, J. T.
Mender, S.
Williams, D. A.
Shen, Z.
Levis, A.
Goddi, C.
Kluge, G. W.
Heß, B.
Nagar, N. M.
Strišković, J.
Ning, W.
Michelson, P. F.
Chibueze, O.
Chandra, S.
SooHoo, J.
Alef, W.
Wardle, J.
Wunderlich, C.
Fish, V. L.
Spencer, S.
Rainò, S.
Talluri, A. K.
Huang, L.
Sobczynska, D.
Ren, H.
Rezzolla, L.
Liu, Q.
Nozaki, S.
Paiano, S.
Horns, D.
Nair, D. G.
Mangano, S.
Ribó, M.
Benbow, W.
Roellinghoff, G.
Pu, H.-Y.
Morcuende, D.
Spolon, A.
Láinez, M.
Mirzoyan, R.
Christiansen, J. L.
Rudak, B.
Liodakis, I.
Akiyama, K.
Rawlings, M. G.
Gasparyan, S.
Escudero, J.
Dzib, S. A.
Bremer, M.
Mulaudzi, W.
Larsson, S.
Sliusar, V.
Ho, L. C.
Delgado, J.
Dmytriiev, A.
Broderick, A. E.
Cheung, C. C.
Aharonian, F.
Cheng, X.
Chibueze, J.
Schuster, K.-F.
Burger-Scheidlin, C.
Yoon, D.
Sabri, K.
Terrier, R.
Feijen, K.
Bolmont, J.
Galison, P.
Souccar, K.
Ait Benkhali, F.
Kim, J.-Y.
Ho, P.
Montgomery, J.
Cui, L.
Korzoun, N.
Bernete, J.
García López, R. J.
Dahale, R.
Saito, T.
Romero-Cañizales, C.
Cruz-Osorio, A.
Pühlhofer, G.
Vitale, V.
Wong, S. L.
van Bemmel, I.
López-Oramas, A.
Zdziarski, A. A.
Wharton, R.
Tluczykont, M.
Wondrak, M. F.
Jankowsky, F.
Horan, D.
Zhang, S.
Delgado Mendez, C.
Hervet, O.
Janssen, M.
Bustamante, S.
Schubert, J. L.
Suda, Y.
Rieger, F.
Kouch, P. M.
Wang, J.
Mohrmann, L.
Jiang, W.
Opis:
Context. The nearby elliptical galaxy M87 contains one of only two supermassive black holes whose emission surrounding the event horizon has been imaged by the Event Horizon Telescope (EHT). In 2018, more than two dozen multi-wavelength (MWL) facilities (from radio to γ-ray energies) took part in the second M87 EHT campaign. Aims. The goal of this extensive MWL campaign was to better understand the physics of the accreting black hole M87*, the relationship between the inflow and inner jets, and the high-energy particle acceleration. Understanding the complex astrophysics is also a necessary first step towards performing further tests of general relativity. Methods. The MWL campaign took place in April 2018, overlapping with the EHT M87* observations. We present a new, contemporaneous spectral energy distribution (SED) ranging from radio to very high-energy (VHE) γ-rays as well as details of the individual observations and light curves. We also conducted phenomenological modelling to investigate the basic source properties. Results. We present the first VHE γ-ray flare from M87 detected since 2010. The flux above 350 GeV more than doubled within a period of ≈36 hours. We find that the X-ray flux is enhanced by about a factor of two compared to 2017, while the radio and millimetre core fluxes are consistent between 2017 and 2018. We detect evidence for a monotonically increasing jet position angle that corresponds to variations in the bright spot of the EHT image. Conclusions. Our results show the value of continued MWL monitoring together with precision imaging for addressing the origins of high-energy particle acceleration. While we cannot currently pinpoint the precise location where such acceleration takes place, the new VHE γ-ray flare already presents a challenge to simple one-zone leptonic emission model approaches, and it emphasises the need for combined image and spectral modelling.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
Tytuł:
Long-term safety and effectiveness of berotralstat for hereditary angioedema : The open-label APeX-S study
Autorzy:
Hagin, David
Zubrinich, Celia
Dobo, Sylvia M.
Kinaciyan, Tamar
Farkas, Henriette
Steiner, Urs C.
Kiani-Alikhan, Sorena
Iocca, Heather A.
Lindsay, Karen
Stobiecki, Marcin
Sheridan, William P.
Jeseňák, Miloš
Desai, Bhavisha
Aygören-Pürsün, Emel
Fain, Olivier
Huissoon, Aarnoud
Maurer, Marcus
Peter, Jonny
Bygum, Anette
Cornpropst, Melanie
Reshef, Avner
Best, Jessica M.
Murray, Sharon C.
Panovska, Vesna Grivcheva
Dix, Daniel
Nagy, Eniko
Wu, Adrian
Opis:
Background: Berotralstat (BCX7353) is an oral, once-daily inhibitor of plasma kallikrein recently approved for prevention of angioedema attacks in adults and adolescents with hereditary angioedema (HAE). The objective of this report is to summarize results from an interim analysis of an ongoing long-term safety study of berotralstat in patients with HAE. Methods: APeX-S is an ongoing, phase 2, open-label study conducted in 22 countries (ClinicalTrials.gov, NCT03472040). Eligible patients with a clinical diagnosis of HAE due to C1 inhibitor deficiency (HAE-C1-INH) were centrally allocated to receive berotralstat 150 or 110 mg once daily. The primary objective was to determine long-term safety and the secondary objective was to evaluate effectiveness. Results: Enrolled patients (N = 227) received berotralstat 150 mg (n = 127) or 110 mg (n = 100) once daily. The median (range) duration of exposure was 342 (11–540) and 307 (14–429) days for the 150-mg and 110-mg groups, respectively. Treatment-emergent adverse events (TEAEs) occurred in 91% (n = 206) of patients. The most common TEAEs across treatment groups were upper respiratory tract infection (n = 91, 40%), abdominal pain (n = 57, 25%), headache (n = 40, 18%), and diarrhea (n = 31, 14%) and were mostly mild to moderate. Fifty percent (n = 113) of patients had at least one drug-related adverse event (AE; 150 mg, n = 57 [45%]; 110 mg, n = 56 [56%]), and discontinuations due to AEs occurred in 19 (8%) patients (150 mg, n = 13 [10%]; 110 mg, n = 6 [6%]). Three (1.3%) patients experienced a drug-related serious TEAE. Among patients who received berotralstat through 48 weeks (150 mg, n = 73; 110 mg, n = 30), median HAE attack rates were low in month 1 (150 mg, 1.0 attacks/month; 110 mg, 0.5 attacks/month) and remained low through 12 months (0 attacks/month in both dose groups). Mean HAE attack rates followed a similar trend, and no evidence for patient tolerance to berotralstat emerged. In both dose groups, angioedema quality of life scores showed clinically meaningful changes from baseline. Conclusions: In this analysis, both berotralstat doses, 150 and 110 mg once daily, were generally well tolerated. Effectiveness results support the durability and robustness of berotralstat as prophylactic therapy in patients with HAE.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
    Wyświetlanie 1-2 z 2

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