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Wyszukujesz frazę "Tran, Anh P." wg kryterium: Autor


Wyświetlanie 1-4 z 4
Tytuł:
Variation in the Lipid Profile of Pacific Oyster (Crassostrea gigas) Cultured in Khanh Hoa Coast, Vietnam, Based on Location and Harvest Period
Autorzy:
Nguyen, Minh V.
Kakooza, Derrick
Tran, Anh P.
Tran, Vy T.
Tematy:
fatty acids
farming location
harvest season
lipid profile
phospholipids
thrombogenicity index
Pokaż więcej
Wydawca:
Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk w Olsztynie
Powiązania:
https://bibliotekanauki.pl/articles/28408446.pdf  Link otwiera się w nowym oknie
Opis:
The lipid profiles of the oyster Crassostrea gigas cultured in Khanh Hoa coast at three locations and harvested in different months throughout the year were compared. Seasonal and locational changes in total lipid (TL) content, phospholipid content, free fatty acid content, fatty acid (FA) composition, and thrombogenicity index were found. The total lipid content and n-3/n-6 ratio in oysters from Ninh Hoa were higher compared to those from Cam Lam and Van Ninh. For oyster from all three farming areas, the total lipid content was the lowest during the two spawning seasons (May and September). Lipids from C. gigas were separated into neutral and polar lipid fractions using silica gel column chromatography. The amount of neutral lipids recovered from the oyster muscle was significantly higher than that of the polar lipids. The FA composition showed that C. gigas was abundant in saturated fatty acids (30.89–39.16 g/100 g TL), followed by polyunsaturated fatty acids (28.13–35.88 g/100 g TL), and monounsaturated fatty acids (19.32–23.75 g/100 g TL). The dominant polyunsaturated fatty acids of oysters from the three farming areas were eicosapentaenoic acid (9.09–13.77 g/100 g TL) and docosahexaenoic acid (6.71–16.47 g/100 g TL). Based on the present findings, it can be concluded that the Pacific oyster C. gigas cultured in Khanh Hoa, Vietnam is a promising source of highly nutritious exploitable lipids.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Fatty Acid Composition and Anticancer Activity of Neutral and Polar Lipids of Pacific Oyster (Crassostrea gigas) Cultured in Khanh Hoa Coast in Vietnam
Autorzy:
Nguyen, Minh V.
Kakooza, Derrick
Do, Thi Hong Tuoi
Tran, Anh P.
Nguyen, Han T.
Tran, Ngoc Q.
Tematy:
anticancer activity
fatty acid profile
lipid fraction
n3/n6 ratio
thrombogenicity
Pokaż więcej
Wydawca:
Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk w Olsztynie
Powiązania:
https://bibliotekanauki.pl/articles/31341116.pdf  Link otwiera się w nowym oknie
Opis:
In this study, we investigated the fatty acid composition and anticancer activity of neutral and polar lipid fractions extracted from Crassostrea gigas oysters cultured in Nha Phu Lagoon, Khanh Hoa Coast, harvested during the five months of January, April, May, September, and November. Analysis revealed that saturated fatty acids (SFAs) were the most abundant fatty acids in the neutral lipid fraction, followed by monounsaturated fatty acids (MUFAs) and polyunsaturated fatty acids (PUFAs). Conversely, the polar lipid fraction exhibited a different order, with PUFAs being the most abundant, followed by MUFAs and SFAs. Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) were identified as the most prevalent polyunsaturated fatty acids, while oleic acid and palmitic acid were the predominant monounsaturated and saturated fatty acids, respectively. Notably, the combined content of EPA and DHA in the polar lipid fraction consistently exceeded 30% throughout all five months of analysis. Thrombogenicity index (TI) values ranged from 0.13 to 0.29 for the polar lipid fraction and from 0.6 to 1.1 for the neutral lipid fraction. Moreover, the polar lipid fraction exhibited significantly higher n3/n6 ratios compared to the neutral lipid fraction. The polar lipid fraction exhibited stronger inhibitory effects on the growth of the three cancer cell lines (HepG2, MDA-MB-231, and RD) compared to the neutral lipid fraction. The findings of the present study show that lipids extracted from C. gigas oysters cultured in Khanh Hoa Coast have a weak anticancer activity but may still aid in prevention and treatment of certain cancer types.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of calcination temperatures on optical and magnetic properties of FeWO4 nanoparticles
Autorzy:
Nguyen, Anh Q.K.
Tran, Thi K.N.
Hoang, Bich N.
Quyen, Ngo T.C.
Huynh, Tai T.
Yen, Nguyen P.
Nguyen, Bich N.
Tematy:
Iron tungstate
Calcination temperature
Optical
Magnetic
Hydrothermal synthesis
Pokaż więcej
Wydawca:
Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie
Powiązania:
https://bibliotekanauki.pl/articles/59124200.pdf  Link otwiera się w nowym oknie
Opis:
Calcination temperature is a crucial parameter that can be easily controlled to induce a change in material properties. Herein, iron tungstate (FeWO4) was synthesized via a hydrothermal method using iron(II) sulfate heptahydrate and sodium tungstate dihydrate as precursors and calcined at the temperature between 300°C and 700°C. With increasing calcination temperature, the saturation magnetization of FeWO4 nanoparticles decreased from 6.6 emu/g for FeWO4 to 0.4 emu/g for FeWO4_700, whereas their band gaps increased from 1.95 eV for FeWO4 to 2.20 eV for FeWO4_700. More crystallinity and crystal defects, and morphological changes at higher calcination temperatures contributed to varying magneto-optical properties of FeWO4 nanoparticles.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analysis of hyperforin (St. Johns wort) action at TRPC6 channel leads to the development of a new class of antidepressant drugs
Autorzy:
Heinrich, Markus
Tran, Mai Anh
Schafer, Michael K.E.
Hellmich, Ute A.
Nowak, Gabriel
Muller, Christian P.
Zheng, Fang
Ye, Lian
El Hamdaoui, Yamina
Lichtenstein, Dajana
Alzheimer, Christian
Fritz, Nikolas
Friedland, Kristina
Treccani, Giulia
Schirmeister, Tanja
Braeuning, Albert
Schwickert, Kevin
Weikert, Dorothee
Nurnberg, Bernd
Opis:
St. John’s wort is an herb, long used in folk medicine for the treatment of mild depression. Its antidepressant constituent, hyperforin, has properties such as chemical instability and induction of drug-drug interactions that preclude its use for individual pharmacotherapies. Here we identify the transient receptor potential canonical 6 channel (TRPC6) as a druggable target to control anxious and depressive behavior and as a requirement for hyperforin antidepressant action. We demonstrate that TRPC6 deficiency in mice not only results in anxious and depressive behavior, but also reduces excitability of hippocampal CA1 pyramidal neurons and dentate gyrus granule cells. Using electrophysiology and targeted mutagenesis, we show that hyperforin activates the channel via a specific binding motif at TRPC6. We performed an analysis of hyperforin action to develop a new antidepressant drug that uses the same TRPC6 target mechanism for its antidepressant action. We synthesized the hyperforin analog Hyp13, which shows similar binding to TRPC6 and recapitulates TRPC6-dependent anxiolytic and antidepressant effects in mice. Hyp13 does not activate pregnan-X-receptor (PXR) and thereby loses the potential to induce drug-drug interactions. This may provide a new approach to develop better treatments for depression, since depression remains one of the most treatment-resistant mental disorders, warranting the development of effective drugs based on naturally occurring compounds.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
    Wyświetlanie 1-4 z 4

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