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Wyszukujesz frazę "Wang, Lan" wg kryterium: Autor


Tytuł:
Experiment of the monitoring prestress loss of prestressed concrete beams with damages under static loading
Autorzy:
Wang, Jinbo
Li, Guodong
Lan, Chunguang
Guo, Nan
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Powiązania:
https://bibliotekanauki.pl/articles/2203451.pdf  Link otwiera się w nowym oknie
Opis:
In this paper, based on the feasible method and sensors for the full-scale prestressed monitor, the novel optical fiber sensors and the traditional monitoring sensors will be set up into two prestressed concrete beams with the same geometrical dimensions, material properties, and construction conditions, etc. to investigate the working state of the novel sensors and obtain the evolution law of prestress loss of the prestressed feature component under the static load. The results show that the evolution law of prestress loss of the loaded beam under the condition of no damage state and initial crack is the same as the non-loaded one; however, the prestress loss increases with the increase of time under the situation with the limit crack. The total loss of the prestressed beam with the limit crack is 36.4% without damage. The prestress loss of the prestressed beam under the static load increase with the development of the crack (injury).
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The influence of pollution accumulation on coating aging of UHV line insulators with different suspension height in coal-ash polluted area
Autorzy:
Lan, Lei
Mu, Lin
Wang, Yu
Yuan, Xiaoqing
Wang, Wei
Li, Zhenghui
Tematy:
aging
pollution component
pollution degree
RTV coating
Pokaż więcej
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Powiązania:
https://bibliotekanauki.pl/articles/140717.pdf  Link otwiera się w nowym oknie
Opis:
Room temperature vulcanized (RTV) silicone rubber is widely used to prevent pollution flashover with its excellent hydrophobicity and hydrophobicity transfer. However, RTV coatings are at the risk of deterioration and failure in heavily polluted operating environment. In this paper, RTV coated insulators with different suspension heights operating in coal ash polluted areas were sampled. Pollution degree, pollution composition and aging degree of coatings were tested. The result shows that the insoluble pollution contains Al(OH)3 filler precipitated from RTV coating, which indicates the aging of the RTV coating. The top surface coating is more affected by ultraviolet and rainwater than the bottom surface resulting in more serious degradation. As the pollution degree of the lower phase insulator is heavier than that of the upper phase insulator, the erosion effect of pollution on the RTV coating is more intense. The fillers and rubber molecules of RTV continuously precipitate into the pollution layer, leading to further aging. Therefore, the overall aging degree of the lower insulator coating is more serious than that of the upper insulator coating.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Threshold effect of economic growth on domestic waste production : evidence from China
Autorzy:
Yang, Li
Wang, Hong-Yan
Yi, Lan
Shi, Xiang-Zhen
Deng, Wei
Tematy:
domestic waste
per capita GDP
source reduction
panel threshold regression model
Pokaż więcej
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Powiązania:
https://bibliotekanauki.pl/articles/2203127.pdf  Link otwiera się w nowym oknie
Opis:
Since the implementation of the compulsory sorting of domestic waste policy in China, the participation rate of residents is low, which leads to the unsatisfactory result of terminal reduction of domestic waste. Therefore, the problem of domestic waste reduction still needs to rely on source reduction. Based on the panel data of 29 provincial capitals in China from 2009 to 2018, this study conducts a comprehensive threshold effect test on per capita GDP and other influencing factors of domestic waste production, conducts panel threshold regression for the factors with threshold value, and explores the nonlinear relationship between per capita GDP and domestic waste production under the influence of different threshold variables. The results show that when the urban population density is less than 272 people/km2, the increase of 1% of per capita GDP will lead to a decrease of 0.251% in the domestic waste production, otherwise, it will lead to an increase of 0.249%; when the per capita consumption expenditure is less than the threshold value of 10,260 yuan/year, the influence coefficient of per capita GDP is 0.155, which increases to 0.207 above the threshold. When the share of tertiary industry is taken as the threshold variable, the two threshold values are 61% and 71% respectively. Through the analysis of control variables, it has been found that population size and amount of courier per capita have significant positive effects on domestic waste production, while gas permeability and the number of non-governmental organizations have significant negative effects.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
ANTI-INFLAMMATORY ACTIVITY AND CYTOTOXICITY OF DIOSGENIN ON LIPOPOLYSACCHARIDES INDUCED RAW 264.7 CELLS
Autorzy:
ning, jing
chang, yu
wang, ruxia
lan, zhiwei
ru, qing
liu, mingchun
tian, chunlian
Tematy:
Diosgenin
Anti-inflammatory
lipopolysaccharides
cytotoxicity
phagocytosis ability  
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Wydawca:
Polskie Towarzystwo Farmaceutyczne
Powiązania:
https://bibliotekanauki.pl/articles/895615.pdf  Link otwiera się w nowym oknie
Opis:
Diosgenin is a steroidal sapogenin compound, and possesses multiple biological activities including anti-inflammatory, anticancer, immunological regulation, and anti-aging. The current study focused on its anti-inflammatory activities and cytotoxicity by analysis of NO production, phagocytosis activity, secretion of TNF-α and IL-6 and cell viability in LPS-induced RAW 264.7 cells. An IC50 value of diosgenin of 2.8 μM was calculated for diosgenin by regression of cell viability from concentrations ranging from 0.01 to 25 μM; this indicated that 0.01, 0.02, 0.04 μM diosgenin could reduce phagocytic activity very significantly (p<0.01) in a dose-dependent manner with no cytotoxic effect on the LPS-induced RAW 264.7 cells. However, there was no significant effect on NO content and secretion of TNF-α and IL-6 after diosgenin treatment. The research revealed that low concentrations diosgenin can directly inhibit cells phagocytosis, with no effect on the release of inflammatory mediators and cytokines. This lays a foundation for screening for a safe dose in research and developent of derivatives and new formulation of diosgenin for its anti-inflammatory effect.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sp100 interacts with phage ΦC31 integrase to inhibit its recombination activity
Autorzy:
Lin, Yun
Li, Zhi-Hui
Wang, Jing-Jing
Xu, Gua-Lan
Shen, Qi
Tian, Lin
Xue, Jin-Lun
Chen, Jin-Zhong
Tematy:
Sp100
ΦC31 integrase
recombination
Pokaż więcej
Wydawca:
Polskie Towarzystwo Biochemiczne
Powiązania:
https://bibliotekanauki.pl/articles/1039951.pdf  Link otwiera się w nowym oknie
Opis:
Phage ΦC31 integrase is a potential vector for the insertion of therapeutic genes into specific sites in the human genome. To understand the mechanism involved in ΦC31 integrase-mediated recombination, it is important to understand the interaction between the integrase and cellular proteins. Using a yeast two-hybrid system with pLexA-ΦC31 integrase as bait, we screened a pB42AD human fetal brain cDNA library for potential interacting cellular proteins. From the 106 independent clones that were screened, 11 potential interacting clones were isolated, of which one encoded C-terminal fragment of Sp100. The interaction between Sp100 and ΦC31 integrase was further confirmed by yeast mating and co-immunoprecipitation assays. The hybridization between a ΦC31 integrase peptide array and an HEK293 cell extract revealed that residues 81RILN84 in the N-terminus of ΦC31 integrase are responsible for the interaction with Sp100. Knocking down endogenous Sp100 with Sp100-specific siRNA increased ΦC31 integrase-mediated recombination but did not impact reporter gene expression. Therefore, endogenous Sp100 may interact with ΦC31 integrase and inhibit the efficiency of ΦC31 integrase-mediated recombination.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Correlation of chromosome damage and promoter methylation status of the DNA repair genes MGMT and hMLH1 in Chinese vinyl chloride monomer (VCM)-exposed workers
Autorzy:
Wu, Fen
Liu, Jing
Qiu, Yu-Lan
Wang, Wei
Zhu, Shou-Min
Sun, Pin
Miao, Wen-Bin
Li, Yong-Liang
Brandt-Rauf, Paul W.
Xia, Zhao-Lin
Tematy:
vinyl chloride monomer
chromosome damage
MGMT
hMLH1
DNA methylation
Pokaż więcej
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Powiązania:
https://bibliotekanauki.pl/articles/2179802.pdf  Link otwiera się w nowym oknie
Opis:
Objective: To explore the association of the methylation status of MGMT and hMLH1 with chromosome damage induced by vinyl chloride monomer (VCM). Materials and Methods: Methylation of MGMT and hMLH1 was measured in 101 VCM-exposed workers by methylation-specifi c PCR. Chromosome damage in peripheral blood lymphocytes was measured by the cytokinesis-block micronucleus assay. The subjects were divided into chromosome damaged and non-damaged groups based on the normal reference value of micronuclei frequencies determined for two control groups. Results: MGMT promoter methylation was detectable in 5 out of 49 chromosome damaged subjects, but not in the chromosome non-damaged subjects; there was a signifi cant difference in MGMT methylation between the two groups (p < 0.05). Conclusions: We detected aberrant promoter methylation of MGMT in a small number of chromosome damaged VCM-exposed workers, but not in the chromosome non-damaged subjects. This preliminary observation warrants further investigation in a larger study.
Dostawca treści:
Biblioteka Nauki
Artykuł

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