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Wyświetlanie 1-10 z 13
Tytuł:
Air pollution during infancy and lung function development into adolescence : the GINIplus/LISA birth cohorts study
Autorzy:
Markevych, Iana
Zhao, Qi
von Berg, Andrea
Gappa, Monika
Schulz, Holger
Heinrich, Joachim
Schikowski, Tamara
Kress, Sara
Koletzko, Sibylle
Bauer, Carl-Peter
Standl, Marie
Berdel, Dietrich
Opis:
Background: limited evidence exists on how air pollution exposure during infancy, i.e. the first year of life, may affect lung function development into adolescence. Objectives: to investigate the association between exposure to air pollution during the first-year of life and lung function development up to the age of 15 in Germany. Methods: we investigated 915 children from the GINIplus and LISA birth cohorts from Munich (n =181) and Wesel (n =734), who had at least two spirometric measurements at ages 6, 10 and 15. Z-scores of forced expiratory volume in one second (FEV1) and forced vital capacity (FVC) were calculated. Annual average con-centrations of nitrogen dioxide, particulate matter with diameters <2.5, <10 and 2.5-10 μm (PM2.5/10/coarse), and PM2.5 absorbance at home addresses during the first-year of life, were estimated by land-use regression models. Associations between infancy exposure and lung function changes were fitted using multivariable linear mixed models with adjustment for potential confounders. Results: for per interquartile range increase in air pollutants during the first-year life, FEV1 z-scores declined annually by -0.012 (95% confidence interval (CI): -0.014, -0.009) for PM2.5 to -0.023 (95%CI: -0.028, -0.018) for PMcoarse. The declines in FVC were lower than FEV1 [-0.006 (95%CI: -0.008, -0.003) to -0.011 (95%CI: -0.019, -0.003)]. In Munich, the attenuations were only significant for FEV1. Effect estimates of infancy exposure for certain air pollutants were higher for groups with asthma, older maternal age, and breastfeeding <12 weeks than their counterparts. Discussion: infancy exposure to higher air pollution may reduce lung function development up to adolescence, with airway size more affected than lung volume restriction. The potential modifying effects of maternal age, asthmatic status of children and breastfeeding warrant further exploration.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
Tytuł:
Impact of residential green space on sleep quality and sufficiency in children and adolescents residing in Australia and Germany
Autorzy:
Standl, Marie
Herberth, Hunda
Flexeder, Claudia
Koletzko, Sibylle
Feng, Xiaoqi
von Berg, Andrea
Bauer, Carl-Peter
Berdel, Dietrich
Heinrich, Joachim
Astell-Burt, Thomas
Schikowski, Tamara
Markevych, Iana
Opis:
Increasing evidence suggests adults living in greener areas tend to have more favourable sleep-related outcomes, but children and adolescents are under-researched. We hypothesised that children and adolescents living in greener areas would have better quality and more sufficient levels of sleep on average, especially within the context of high traffic noise exposure. These hypotheses were tested using multilevel logistic regressions fitted on samples from the nationally representative Longitudinal Study of Australian Children (10-11 years old, n = 3469, and 14-15 years old, n = 2814) and the GINIplus and LISA cohorts (10 years old, n = 1461, and 15 years old, n = 4172) from the Munich, Wesel, and Leipzig areas of Germany. Questionnaire-based binary indicators of sleep sufficiency and sleep quality in each cohort were assessed with respect to objectively measured green space exposures adjusting for age, sex, and maternal education. Models were augmented with proxy measures of traffic noise and two-way interaction terms to test for effect modification. Cross-tabulations illustrated little convincing evidence of association between green space and insufficient sleep or poor sleep quality in either sample, except for insufficient sleep among 10 year old participants in Germany. These null findings were replicated in adjusted models. The proxy for traffic noise was associated with poor quality sleep in 15 year old participants in Germany, but no convincing evidence of modified association with green space was observed.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
Tytuł:
Outdoor air pollution and hormone-assessed pubertal development in children : results from the GINIplus and LISA birth cohorts
Autorzy:
Standl, Marie
Bauer, Carl-Peter
Altug, Hicran
Schikowski, Tamara
Heinrich, Joachim
Markevych, Iana
Zhao, Tianyu
Triebner, Kai
de Hoogh, Kees
Berdel, Dietrich
Nowak, Dennis
Koletzko, Sibylle
von Berg, Andrea
Opis:
Background: Air pollution is hypothesized to affect pubertal development. However, the few studies on this topic yielded overall mixed results. These studies did not consider important pollutants like ozone, and none of them involved pubertal development assessed by estradiol and testosterone measurements. We aimed to analyze as-sociations between long-term exposure to four pollutants and pubertal development based on sex hormone concentrations among 10-year-old children. Methods: These cross-sectional analyses were based on the 10-year follow-up medical examinations of 1945 children from the Munich and Wesel centers of the GINIplus and LISA German birth cohorts. Female and male pubertal development was assessed by dichotomizing the concentration of hormones in serum at 18.4 pmol/L and 0.087 nmol/L using the lower limits of quantification for estradiol and testosterone, respectively. Land-use regression models derived annual average concentrations of particulate matter with an aerodynamic diameter <2.5 and 10 μm (PM2.5 and PM10), as well as spatial models assessed yearly average concentrations of nitrogen dioxide (NO2) and ozone, were calculated at the 10-year residential addresses. To evaluate associations, we utilized logistic regressions adjusted for potential covariates. The analyses were stratified by area and sex. Results: Around 73% of the 943 females and 25% of the 1002 males had a high level of hormones and had already started puberty at the age of 10. Overall, we found no statistically significant associations between exposure to particles (PM2.5 or PM10) and pubertal development. Results on NO2 and ozone were not significant as well; for instance, per 10 μg/m3 increase in ozone concentration, odds ratios and 95% confidence intervals were 0.900 (0.605, 1.339) and 0.830 (0.573, 1.203) for females and males, respectively. Stratified by area, the aforemen-tioned results did not reveal any associations either. Conclusions: Our study did not observe the associations between ambient air pollutants and pubertal development determined by estradiol and testosterone levels in children. However, due to the current limited number of studies on this topic, our results should be cautiously interpreted. Future longitudinal studies are needed to assess the association.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
Tytuł:
Air pollution and IgE sensitization in four European birth cohorts : the MeDALL project
Autorzy:
Thiering, Elisabeth
Bousquet, Jean
Kull, Inger
Markevych, Iana
Koppelman, Gerard H
Bergström, Anna
Wijga, Alet
Berdel, Dietrich
Heinrich, Joachim
Melén, Erik
Wickman, Magnus
Gruzieva, Olena
Lupinek, Christian
Standl, Marie
von Berg, Andrea
Antó, Josep Maria
van Hage, Marianne
Valenta, Rudolf
Gehring, Ulrike
Vonk, Judith M
Altug, Hicran
Schikowski, Tamara
Opis:
Background: whether long-term exposure air to pollution has effects on allergic sensitization is controversial. Objective: our aim was to investigate associations of air pollution exposure at birth and at the time of later biosampling with IgE sensitization against common food and inhalant allergens, or specific allergen molecules, in children aged up to 16 years. Methods: a total of 6163 children from 4 European birth cohorts participating in the Mechanisms of the Development of ALLergy [MeDALL] consortium were included in this metaanalysis of the following studies: Children, Allergy, Milieu, Stockholm, Epidemiology (BAMSE) (Sweden), Influences of Lifestyle-Related Factors on the Human Immune System and Development of Allergies in Childhood (LISA)/German Infant Study on the Influence of Nutrition Intervention PLUS Environmental and Genetic Influences on Allergy Development (GINIplus) (Germany), and Prevention and Incidence of Asthma and Mite Allergy (PIAMA) (The Netherlands). The following indicators were modeled by land use regression: individual residential outdoor levels of particulate matter with aerodynamic diameters less than 2.5 mm, less than 10 mm, and between 2.5 and 10 mm; PM2.5 absorbance (a measurement of the blackness of PM2.5 filters); and nitrogen oxides levels. Blood samples drawn at ages 4 to 6 (n 5 5989), 8 to 10 (n 5 6603), and 15 to 16 (n 5 5825) years were analyzed for IgE sensitization to allergen extracts by ImmunoCAP. Additionally, IgE against 132 allergen molecules was measured by using the MedALL microarray chip (n 5 1021). Results: air pollution was not consistently associated with IgE sensitization to any common allergen extract up to age 16 years. However, allergen-specific analyses suggested increased risks of sensitization to birch (odds ratio [OR] 5 1.12 [95% CI 5 1.01-1.25] per 10-mg/m3 increase in NO2 exposure). In a subpopulation with microarray data, IgE to the major timothy grass allergen Phleum pratense 1 (Phl p 1) and the cat allergen Felis domesticus 1 (Fel d 1) greater than 3.5 Immuno Solid-phase Allergen Chip standardized units for detection of IgE antibodies were related to PM2.5 exposure at birth (OR 5 3.33 [95% CI 5 1.40-7.94] and OR 5 4.98 [95% CI 5 1.59-15.60], respectively, per 5-mg/m3 increase in exposure). Conclusion: air pollution exposure does not seem to increase the overall risk of allergic sensitization; however, sensitization to birch as well as grass pollen Phl p 1 and cat Fel d 1 allergen molecules may be related to specific pollutants.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
Tytuł:
Gestational weight gain charts for different body mass index groups for women in Europe, North America, and Oceania
Autorzy:
Hertz-Picciotto, Irva Hertz-Picciotto
Jaddoe, Vincent W.V.
Trnovec, Tomas
Eggesbo, Merete
Voerman, Ellis
Heude, Barbara
Morgen, Camilla S.
Torrent, Maties
Pizzi, Costanza
van Buuren, Stef
Eekhout, Iris
Pac, Agnieszka
Jusko, Todd A.
Koletzko, Berthold
Santos, Susana
Magnus, Per
Chatzi, Leda
Thijs, Carel
Nybo Andersen, Anne-Marie
Thiering, Elisabeth
Gaillard, Romy
Richiardi, Lorenzo
Sorensen, Thorkild I.A.
Karvonen, Anne M.
Makela, Johanna
Santa-Marina, Loreto
Majewska, Renata
Inskip, Hazel
Georgiu, Vagelis
Porta, Daniela
Gori, Davide
Farchi, Sara
Hivert, Marie-France
Lehmann, Irina
Hryhorczuk, Daniel
Grote, Veit
Chrousos, George P.
Corpeleijn, Eva
Doyon, Myriam
Mommers, Monique
Oken, Emily
Lawlor, Debbie A.
Vrijheid, Martine
van Rossem, Lenie
van Gelder, Marleen M.H.J.
Stanislawski, Maggie
Fantini, Maria Pia
Papadopoulou, Eleni
Crozier, Sarah
Pekkanen, Juha
Roeleveld, Nel
Smit, Henriette A.
Standl, Marie
Murínova, Lubica
Costet, Nathalie
Lagstrom, Hanna
Chevrier, Cecile
von Berg, Andrea
Moschonis, George
Godfrey, Keith M.
Santos, Ana C.
Vrijkotte, Tanja G.M.
Barros, Henrique
Zvinchuk, Oleksandr
Rifas-Shiman, Sheryl L.
Hanke, Wojciech
Stoltenberg, Camilla
Forastiere, Francesco
Nohr, Ellen A.
Polanska, Kinga
Oostvogels, Adriette J.J.M.
Manios, Yannis
Gagliardi, Luigi
Huang, Rae-Chi
Lopez-Espinosa, Maria-Jose
Newnham, John
Charles, Marie-Aline
McDonald, Sheila W.
Tough, Suzanne C.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
Wyświetlanie 1-10 z 13

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