Temat: Antibacterial activity

Skocz do pozycji: 1.

Tytuł:: Synthesis, antiprotozoal and antibacterial activity of nitro- and halogeno-substituted benzimidazole derivatives.
Autorzy:: Kazimierczuk, Zygmunt
Upcroft, Jacqueline
Upcroft, Peter
Górska, Agata
Starościak, Bohdan
Laudy, Agnieszka
Tematy:: antibacterial activity
antiprotozoal activity
benzimidazoles; Pokaż więcej
Wydawca:: Polskie Towarzystwo Biochemiczne
Powiązania:: https://bibliotekanauki.pl/articles/1043825.pdf Link otwiera się w nowym oknie
Opis:: Two series of benzimidazole derivatives were sythesised. The first one was based on 5,6-dinitrobenzimidazole, the second one comprises 2-thioalkyl- and thioaryl-substituted modified benzimidazoles. Antibacterial and antiprotozoal activity of the newly obtained compounds was studied. Some thioalkyl derivatives showed remarkable activity against nosocomial strains of Stenotrophomonas malthophilia, and an activity comparable to that of metronidazole against Gram-positive and Gram-negative bacteria. Of the tested compounds, 5,6-dichloro-2-(4-nitrobenzylthio)-benzimidazole showed the most distinct antiprotozoal activity.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Nanosilver - does it have only one face?
Autorzy:: Likus, Wirginia
Bajor, Grzegorz
Siemianowicz, Krzysztof
Tematy:: silver nanoparticles
antibacterial activity
toxicology; Pokaż więcej
Wydawca:: Polskie Towarzystwo Biochemiczne
Powiązania:: https://bibliotekanauki.pl/articles/1039429.pdf Link otwiera się w nowym oknie
Opis:: Silver nanoparticles (NPs) have at least one dimension of a particle smaller than 100 nm and contain 20-15,000 silver atoms. Due to its antibacterial activity nanosilver (NS) is used for medical purposes. NS particles can be obtained by various methods. Potentially, the best method of the NS synthesis for medical purposes is based on a brief flow of electric current between two silver electrodes placed in deionized water. It is accepted that the major antibacterial effect of silver is its partial oxidation and releasing silver ions, which interact with thiol groups of peptidoglicans of bacterial cell wall, and proteins of the cell membrane causing cell lysis. Silver ions can also bind to bacterial DNA preventing its replication and stopping synthesis of bacterial proteins. The rise in exposure to silver NPs has spurred interest into their toxicology. NS undergoes a set of biochemical transformations including accelerated oxidative dissolution in gastric acid, binding to thiol groups of serum and tissue proteins, exchange between thiol groups, sulfides and selenides, binding to selenoproroteins and photoreduction in skin to zerovalent metallic silver. Animal studies have shown that exposure to NS may lead to liver and spleen damage. NS can also stimulate an increased secretion of proinflammatory cytokines by monocytes. As a spectrum of NS applications is still growing, the complex evaluation of a safety of its use becomes an important task. This requires an elucidation of not only the influence of NS on human cells and organism, but also its biotransformation in organism and in environment.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Biomaterials with antibacterial activity
Autorzy:: Wysocka, K.
Buzalewicz, I.
Wieliczko, A.
Kowal, K.
Stręk, W.
Podbielska, H.
Tematy:: biomaterials
silver nanoparticles
antibacterial activity; Pokaż więcej
Wydawca:: Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Powiązania:: https://bibliotekanauki.pl/articles/284386.pdf Link otwiera się w nowym oknie
Opis:: The sol-gel derived silica spheres with surfaces modified by silver nanoparticles were used to enhance the photodynamic effect. The silica nanoparticles were prepared by modified Stöber synthesis. The diameter of obtained silica spheres was ca. 100 nm. These silica spheres we used as a carrier for noble nanoparticles. It was shown that Ag-Au nanoparticles have an antibacterial activity against Escherichia coli. This effect depends on the nanoparticles concentration and it is stronger for higher concentrations. Laser irradiation enhances this effect, and starting from certain concentration it is possible to kill Escherichia coli, totally, when using laser light.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Chitosan-silver nanocomposites : modern antibacterial materials
Nanokompozyty chitozanowo-srebrowe : nowoczesne materiały antybakteryjne
Autorzy:: Kyzioł, Agnieszka
Arruebo, Manuel
Regiel-Futyra, Anna
Opis:: One of the most threatening problem of nowadays civilization are bacterial infections. Often unjustified administration of antibiotics have forced bacterial strains to develop evolutionary adaptations which make them more resistant for traditional drugs. Recently hybrid materials, based on silver nanoparticles and biodegradable polymers (e.g. chitosan), have gathered much of scientists attention. In this paper we summarize current achievements of chitosan-silver nanocomposites efficacy in bacterial infection control
Dostawca treści:: Repozytorium Uniwersytetu Jagiellońskiego

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Skocz do pozycji: 5.

Tytuł:: Bioactive glasses enriched with zinc and strontium: synthesis, characterization, cytocompatibility with osteoblasts and antibacterial properties
Autorzy:: Ciołek, Lidia
Chraniuk, Milena
Bollin, Piotr
Biernat, Monika
Panasiuk, Mirosława
Nidzworski, Dawid
Gromadzka, Beata
Jaegermann, Zbigniew
Pamuła, Elżbieta
Tematy:: bioglass
bioactivity
cytotoxicity
antibacterial activity; Pokaż więcej
Wydawca:: Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Powiązania:: https://bibliotekanauki.pl/articles/56032097.pdf Link otwiera się w nowym oknie
Opis:: The aim of the presented work was to characterize the new obtained bioglasses and assess their biological performance in vitro. Bioglasses were produced using the sol-gel method in the SiO2-P2O5-CaO system, for the purpose as composite ingredients. Their chemical composition was enriched with ZnO to introduce antibacterial properties and SrO with osteoinductive effect. The properties of bioglasses were compared and the effect of chemical composition and particle size on their biological properties was assessed. Methods: The bioglasses were evaluated via TG-DTA, FTIR, SEM-EDS analyses before and after incubation in SBF solution. LDH and WST-1 tests were used to determine the level of cytotoxicity of the tested bioglasses on hFOB1.19 osteoblasts. Results: The results show that the developed bioglasses release Ca2+, are bioactive in SBF solution, not cytotoxic and show antibacterial activity in contact with Pseudomonas aeruginosa and Staphylococcus aureus strains. Bioglasses enriched with ZnO show the highest bactericidal activity. All tested bioglasses enhanced hFOB 1.19 cells proliferation. Particle size has a lower effect on biological performance of the bioglasses than their chemical composition. Conclusions: The conducted research showed that bioglass modification with SrO and ZnO can be considered particularly for the development of biomaterials supporting bone regeneration and the treatment of infected bone defects.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 6.

Tytuł:: Formation and properties of dbc/pla microfibres
Autorzy:: Biniaś, Dorota
Biniaś, Włodzimierz
Machnicka, Alicja
Janicki, Jarosław
Hałuszka, Patrycja
Tematy:: PLA
antibacterial activity
dibutyrylchitin
electrospinning
microfibres; Pokaż więcej
Wydawca:: Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Powiązania:: https://bibliotekanauki.pl/articles/1034598.pdf Link otwiera się w nowym oknie
Opis:: In this study, a solution of dibutyrylchitin (DBC)/polylactide (PLA) blend micro and nanofibres were successfully fabricated using blends of 2,2,2-trifluoroethanol (TFE) as solvents. Fibres were produced from the solutions by electrospinning. The DBC/PLA blend solutions in various ratios were studied for electrospinning into micro/nanofibres. The morphology of the micro and nanofibres was observed by scanning electron microscope (SEM). The biggest diameters of DBC/PLA fibres were obtained for the blended microfibres in ratios of 10/90 and 25/75. The smallest diameter was observed for pure polymers. The antibacterial properties were examined for materials obtained by electrospinning. In the experiments, materials with antibacterial properties were made. It is likely that the electrospun micro and nanofibres will be used in the native extracellular matrix for tissue engineering.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 7.

Tytuł:: Highly developed construction of Heterostructured InWO3-InMoO3 loaded-TiO2 nanomaterial and Expanding multi-application
Autorzy:: Kamalakkannan, J.
Senthilvelan, S.
Tematy:: HR-TEM
Photocatalytic
antibacterial activity
electrochemical study; Pokaż więcej
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Powiązania:: https://bibliotekanauki.pl/articles/1178704.pdf Link otwiera się w nowym oknie
Opis:: InWO3-InMoO3 loaded-TiO2 nanomaterial was synthesised by co-precipitation method and sonication technique. The nanomaterial was characterized by High-resolution scanning electron microscopy (HR-SEM) with elementary dispersive X-ray (EDX), High-resolution transmission electron microscopy (HR-TEM), photoluminescence spectroscopy (PL) and UV-Vis diffuse reflectance spectroscopy (DRS). The photocatalytic activity of InWO3-InMoO3 loaded-TiO2 nanomaterial was studied from the photodegradation of methyl green (MEG) and methylene blue (MB) under UV-light irradiation at 365 nm. The hydroxyl radical formation in the mechanism was confirmed by fluorescence quenching technique. The mineralization confirmed by chemical oxygen demand measurements. A flaxisible mechanism is proposed for higher catalytic activity of InWO3-InMoO3-TiO2 under UV-light for 365 nm. This catalyst was found to be stable and reusable without appreciable loss of catalytic activity up to five cycles. The InWO3- InMoO3 loaded-TiO2 nanomaterial on MEG was high photocatalytic activity that of MB so high photocatalytic activity has been discussed by first order kinetics, rate constant value and high quantum yield. This material was showed increased hydrophobicity that of TiO2 electrochemical study and antibacterial activity of the analysis was also studied.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 8.

Tytuł:: The in vitro effects of probiotic bacteria on genital pathogens of female dogs
Autorzy:: Szydło, Marlena
Golińska, Edyta
Witka, Natalia
Lenarczyk, Joanna
Arent, Zbigniew
Sowińska, Natalia
Strus, Magdalena
Opis:: Background An important aspect in the microbiology of the reproductive system of small animals is the potential occurrence of probiotic bacteria, such as lactic acid bacteria (LAB) of the genus Lactobacillus. The presence of these microorganisms is significant due to their strong antibacterial and antifungal properties. This study aimed to select probiotic strains from the oral cavity and vagina that have outstanding antibacterial properties against typical genital pathogens of the female dog reproductive tract. Results The antagonistic activity of ten LAB strains was tested against seven etiological agents isolated from the genital tract of female dogs with signs of inflammation. LAB strains with the greatest ability to inhibit the growth of indicator bacteria were Lactobacillus plantarum and L. acidophilus, while L. fermentum and L. brevis strains inhibited growth the least. Almost all strains showed a complete lack of adherence to Caco-2 epithelial cells. Conclusions All tested LAB isolates inhibited the in vitro growth of either Gram-positive or Gram-negative pathogens, suggesting that potential probiotic strains could contribute to the balance of the normal vaginal microbiota. Furthermore, they could be considered for use as prophylactic agents or as an alternative to antibiotic therapy for infections in dogs.
Dostawca treści:: Repozytorium Uniwersytetu Jagiellońskiego

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Skocz do pozycji: 9.

Tytuł:: Biological activities and chemical composition of solvent extracts of Stoechospermum marginatum (C. Agardh)
Autorzy:: Esmaeili, Akbar
Khakpoor, Marjan
Tematy:: brown seaweed
antibacterial activity
Stoechospermum marginatum
extract
antioxidant activity; Pokaż więcej
Wydawca:: Polskie Towarzystwo Biochemiczne
Powiązania:: https://bibliotekanauki.pl/articles/1039656.pdf Link otwiera się w nowym oknie
Opis:: The objective of this study was to evaluate the chemical composition CH3OH-CH2Cl2 (1:1) extract and biological activities of various extracts derived from the aerial parts of the brown marine alga Stoechospermum marginatum (C. Agardh). Gas chromatography (GC) and gas chromatography-mass spectroscopy (GC-MS) were used to analyze the composition of the essential oil. Total phenolics assay demonstrated a high value in hexane extract (HE), with a lower value for chloroform extract (CE), and the lowest value for methanol extract (ME). DPPH (2,2-diphenyl-1-picrylhydrazyl) assay showed that extracts of S. marginatum possess radical scavenging activity (RSA). Tests of the antioxidant property of the extracts revealed both electron and hydrogen transfer mechanisms. The antibacterial activity of the ME, CE, and HE as well as an ethanol extract was estimated against seven Gram-positive and Gram-negative bacteria. The ethanol extract showed the highest antibacterial activity, and the HE showed the lowest.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 10.

Tytuł:: Synthesis and antimicrobial activity of substituted (E)-1-(4-fluoro-3-methylphenyl)-3-phenylprop-2-en-1-one compounds
Autorzy:: Balaji, S.
Senbagam, R.
Rajarajan, M.
Vijayakumar, R.
Manikandan, V.
Vanangamud, G.
Thirunarayanan, G.
Tematy:: Antibacterial activity
Antifungal activity
Bacillus subtilis
vibrio cholera; Pokaż więcej
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Powiązania:: https://bibliotekanauki.pl/articles/1189942.pdf Link otwiera się w nowym oknie
Opis:: In an effort to develop antimicrobial agents, a series of substituted (E)-1-(4-fluoro-3-methylphenyl)-3-phenylprop-2-en-1-one compounds were synthesized by crossed-aldol condensation reaction of 4-fluoro-3-methyl acetophenone with various substituted benzaldehydes in the presence of sodium hydroxide. The synthesized compounds were characterized by means of their UV, IR and NMR spectral data. The synthesized substituted (E)-1-(4-fluoro-3-methylphenyl)-3-phenylprop-2-en-1-one compounds were tested for their antibacterial and antifungal activities by the Bauer-Kirby disc diffusion method.
Dostawca treści:: Biblioteka Nauki

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