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Wyszukujesz frazę "RAT" wg kryterium: Temat


Tytuł:
Response to spatial and nonspatial change in wild (WWCPS) and Wistar rats
Autorzy:
Stryjek, Rafał
Modlińska, Klaudia
Pisula, Wojciech
Tematy:
Wild rat
laboratory rat
domestication
exploratory behavior
neophobia
Pokaż więcej
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Powiązania:
https://bibliotekanauki.pl/articles/430459.pdf  Link otwiera się w nowym oknie
Opis:
The purpose of the experiment was to investigate the effects of domestication on exploration in rats. The comparison was made between wild Warsaw-Wild-Captive-Pisula-Stryjek (WWCPS) rats and Wistar laboratory rats. The study used a purpose-built maze divided into zones connected with a corridor. Objects were placed in two out of four zones. Their location and shape were subject to experimental manipulation. Transporter used to move rats to the maze provided the opportunity for spontaneous exploration of the experimental arena. Rats were subjected to a series of 10 sessions (habituation), followed by a spatial or nonspatial change in the experimental arena, after which another 5 experimental sessions were conducted. The study revealed that wild rats had much higher exploration latency than their laboratory counterparts. At each analyzed stage, WWCPS rats spent much more time in the transporter than Wistar rats. Wistar rats spent much more time during the experiment on object interaction in the experimental arena. In post-manipulation sessions, however, it was wild rats that explored object zones relatively longer than laboratory rats. No differences in the animals’ behavior depending on the type of change were observed. Results suggest that wild rats tend to explore much more cautiously than laboratory rats and are more sensitive to changes in their environment. The underlying cause of these differences is likely to be the higher level of stress in wild rats, resulting from threats in their natural habitat.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Warsaw Wild Captive Pisula Stryjek rats (WWCPS) - Establishing a breeding colony of Norway Rat in captivity
Autorzy:
Stryjek, Rafał
Pisula, Wojciech
Tematy:
wild rat
wild-type rat
Rattus norvegicus
domestication
Pokaż więcej
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Powiązania:
https://bibliotekanauki.pl/articles/55994149.pdf  Link otwiera się w nowym oknie
Opis:
It is believed that the history of laboratory rat dates back to 1820-ies, which is about 300 generations. This relatively short evolutionary distance, drastically different environment and selective breeding could have caused differences in behaviour between the laboratory rat and his wild counterpart - Norway rat (Rattus norvegicus). The vast majority of research concerning differences between wild and laboratory rats was conducted over 30 years ago. The knowledge acquired as a result of that research seems far from being complete. Over a quarter of a century could have deepened the described differences. Nowadays the change in experimental approach, in favour of low stress conditions, can give a new insight into this problem. This article describes process of establishing a laboratory line of wild Norway rat, which will take part in a broad series of comparative studies. 16 wild rats were trapped in 5 distant parts of Warsaw. Most of wild rats successfully adapted to captive conditions, mating successfully and producing litters, which have survived to adolescence.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Marko Perković jako symbol pokolenia Domovinskog rata we współczesnej Chorwacji
Marko Perkovic as a symbol of generation of the Domovinski rat in a contemporary Croatia.
Autorzy:
Pacek, Mateusz
Opis:
Autor opisuje przyczyny popularności artysty w Chorwacji, analizuje zjawiska związane z gatunkiem "turbofolk" a także przywołuje wydarzenia z historii Chorwacji, które wpłynęły na postrzeganie rzeczywistości w świadomości Chorwatów.
The author describes the popularity of the artist in Croatia, examines the phenomena related to genre ' turbofolk "and recalls events from the history of Croatia, which influenced the perception of reality in the consciousness of the Croats.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Inne
Tytuł:
Animal models of hypertension - revisited
Autorzy:
Polak, A.
Harasim-Symbor, E.
Chabowski, A.
Tematy:
Dahl salt-sensitive rat
Deoxycorticosterone acetate-salt rat
Hypertension
Spontaneously hypertensive rat
Two-kidney one-clip model
Pokaż więcej
Wydawca:
Uniwersytet Medyczny w Białymstoku
Powiązania:
https://bibliotekanauki.pl/articles/1918606.pdf  Link otwiera się w nowym oknie
Opis:
Nowadays, civilization diseases, such as hypertension, are one of the biggest global health problems. In 2017 the threshold for hypertension diagnosis was set at 130/80 mmHg, which resulted in its increased prevalence, reaching nearly 50% of the human population. Therefore, strategies for hypertension prevention and treatment have been recently extensively developing. Nonetheless, growing body of factors which can affect blood pressure and induce hypertension is constantly prompting researchers to conduct experiments in this field. For this purpose, animal models seem to be appropriate and necessary. The present report reviews current findings related to hypertension types and causes. It also presents the main guidelines for high blood pressure prevention and describes different experimental models introduced to be carried out in such studies.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The embryonic development of the submandibular and sublingual salivary glands in the white rat; Rozwój zarodkowy ślinianki podszczękowej i podjęzykowej szczura białego
Autorzy:
Szymańska, Z.
Powiązania:
Acta Theriologica
Opis:
Autorka obserwowała rozwój ślinianki podszczękowej i podjęzykowej szczura białego na materiale składającym się z 42 zarodków długości 22-29 mm.
Dostawca treści:
RCIN - Repozytorium Cyfrowe Instytutów Naukowych
Książka
Tytuł:
Effect of cadmium on collagen content and solubility in rat bone.
Autorzy:
Galicka, Anna
Brzóska, Małgorzata
Średzińska, Krystyna
Gindzienski, Andrzej
Tematy:
rat
collagen
bone
cadmium
Pokaż więcej
Wydawca:
Polskie Towarzystwo Biochemiczne
Powiązania:
https://bibliotekanauki.pl/articles/1041563.pdf  Link otwiera się w nowym oknie
Opis:
The toxic action of cadmium in the bone tissue is known, but its mechanisms are still unexplained. We examined whether Cd influences collagen content and its solubility in the femoral bone of three-week-old female rats exposed to 5 or 50 mg Cd/l in drinking water. Non-cross linked collagen was extracted with 0.5 M acetic acid, and two acid-insoluble collagen fractions were extracted with pepsin and 4.0 M guanidine hydrochloride, respectively. SDS/PAGE showed the presence of two collagen types, I and V, in all three extracted fractions. Exposure of rats to Cd for 6 months increased the amount of acid-soluble collagens type I and V and decreased the level of acid-insoluble collagens. The amount of total collagen extracted from the bones of rats exposed to 50 mg Cd/l was reduced by about 14% as compared to control and those intoxicated with 5 mg Cd/l. The solubility of type I bone collagen (determined as the percentage of acetic-soluble fraction of total collagen) was increased 2.9- and 3.0-fold in rats intoxicated with 5 and 50 mg Cd/l, respectively. Similarly, the solubility of type V collagen was increased 2.3- and 2.7-fold, respectively. Our results indicate that Cd treatment affects bone collagen by decreasing its content and increasing its solubility.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Rat skin as an experimental model in medicine
Autorzy:
Niczyporuk, M.
Tematy:
Rat
skin
experimental medicine
Pokaż więcej
Wydawca:
Uniwersytet Medyczny w Białymstoku
Powiązania:
https://bibliotekanauki.pl/articles/1918822.pdf  Link otwiera się w nowym oknie
Opis:
Scientific experiments due to safety and ethical limitations regarding research human are often based on animal models. Rats are laboratory animals which are commonly used for these purposes. It should be remembered that morphologi- cal and functional differences between rat skin and human skin may refer to the correct interpretation of scientific results.
Dostawca treści:
Biblioteka Nauki
Artykuł

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