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Wyszukujesz frazę "biosynthesis" wg kryterium: Temat


Tytuł:
Evidence for the presence of the Kennedy and Bremer- Greenberg pathways in Caenorhabditis elegans.
Autorzy:
Lochnit, Günter
Geyer, Rudolf
Tematy:
nematodes; choline metabolism; phosphatidylcholine biosynthesis
Pokaż więcej
Wydawca:
Polskie Towarzystwo Biochemiczne
Powiązania:
https://bibliotekanauki.pl/articles/1043417.pdf  Link otwiera się w nowym oknie
Opis:
Nematodes were found to synthesize phosphorylcholine-containing molecules not present in higher organisms, i.e. phosphorylcholine-substituted glycosphingolipids and (glyco)proteins. Investigations on the biosynthesis of these structures provided first biochemical evidence for the presence of the Kennedy and Bremer-Greenberg pathways in the model organism Caenorhabditis elegans.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Magnoflorine - a compound with anti-tumour activity
Autorzy:
Baran, M.
Miziak, P.
Bonio, M.
Tematy:
biosynthesis
alkaloids
antitumour activity
magnoflorin
Pokaż więcej
Wydawca:
Instytut Medycyny Wsi
Powiązania:
https://bibliotekanauki.pl/articles/2097708.pdf  Link otwiera się w nowym oknie
Opis:
Introduction. Alkaloids are a large group of organic compounds of natural origin. One of the most popular alkaloids is magnoflorine. This compound is synthesized by plants from the Ranunculaceae, Menispermaceae and Magnoliaceae families. Magnoflorine has unique biological properties and a broad spectrum of physiotherapeutic activity. It has antibacterial, antifungal, antidiabetic, immunomodulating and anticancer properties. Objective.The aim of the study is to present magnoflorine as a compound with anti-cancer potential. Brief description of the state of knowledge. Magnoflorine is a compound belonging to the isoquinolone alkaloids. Metabolized by secondary metabolism it is most commonly collected in the roots, rhizomes, tubers and bark of plants. It can be isolated from all plant elements by chromatographic methods. Magnoflorine has a number of therapeutic properties, including anti-cancer. Magnoflorine has been shown to inhibit cell proliferation, migration and cause apoptosis. The possibility of using this compound in the treatment of breast and stomach cancer has been confirmed. Results. The combination of DOX with magnoflorine reduces the expression of Bcl-2 and enhances the cleavage of caspase-9 and -3, causing apoptosis in breast cancer cells. Moreover, they block the activation of PI3K / AKT / mTOR signaling, which play an important role in regulating tumour growth. Magnoflorine inhibits the activity of caspases in liver cancer cells, resulting in inhibition of proliferation. Conclusion. Magnoflorine is an interesting research target due to its unique anticancer properties. Detailed knowledge of the pharmacological possibilities of magnoflorine will enable its effective use in the prevention and treatment of many civilization diseases.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Trehaloza – właściwości, biosynteza, zastosowanie
Trehalose – properties, biosynthesis and applications
Autorzy:
Burek, M.
Waśkiewicz, S.
Wandzik, I.
Kamińska, K.
Tematy:
trehaloza
bioprotekcja
biosynteza
trehalose
bioprotection
biosynthesis
Pokaż więcej
Wydawca:
Stowarzyszenie Inżynierów i Techników Przemysłu Chemicznego. Zakład Wydawniczy CHEMPRESS-SITPChem
Powiązania:
https://bibliotekanauki.pl/articles/143174.pdf  Link otwiera się w nowym oknie
Opis:
α,α-Trehaloza jest naturalnie występującym disacharydem, zbudowanym z dwóch cząsteczek glukozy połączonych wiązaniem α,α- 1,1’-O-glikozydowym. Znana jest głównie ze zdolności do stabilizacji białek w warunkach stresu środowiskowego oraz hamowania ich agregacji. Po opracowaniu wielkotonażowej, biotechnologicznej metody produkcji, trehaloza znalazła liczne zastosowania w różnych gałęziach przemysłu, głównie w przemyśle spożywczym, kosmetycznym, farmaceutycznym i medycynie. Dowiedziono, że właściwości bioprotekcyjne trehalozy zostają zintensyfikowane w przypadku jej glikopolimerów.
α,α -Trehalose is naturally occurring disaccharide composed of two glucose molecules linked by α,α -1,1’-O-glycosydic bond. It is primarily known from its ability to protect proteins during environmental stresses and inhibition of their aggregation. The development of largescale bioprocess has allowed to use trehalose in various applications, mainly in the food, cosmetic and pharmaceutical industry as well as in medicine. It was reported that bioprotective properties are amplified when trehalose is incorporated in polymer chain as a pendant group.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Regulation of melatonin biosynthesis in the vertebrate pineal gland - role of the retinal dopaminergic signal
Regulacja biosyntezy melatoniny w szyszynce kregowców - rola siatkówkowego sygnału dopaminergicznego
Autorzy:
Berezińska, Małgorzata
Współwytwórcy:
Zawilska, Jolanta B.
Wydawca:
Zakład Farmakologii Uniwersytetu Medycznego w Łodzi
Centrum Biologii Medycznej PAN
Opis:
Bibliogr. s.143-165
165 s. : ryc. ; 30 cm
Dostawca treści:
RCIN - Repozytorium Cyfrowe Instytutów Naukowych
Książka
Tytuł:
Herbal Extract-Induced Silver Nanoparticles for Antibacterial Cotton Fabric
Autorzy:
Rajput, Sanjeev Kumar
Singh, Mukesh Kumar
Shakyawar, Dinesh Babu
Tematy:
biosynthesis
nanoparticles
natural dye
antibacterial property
Pokaż więcej
Wydawca:
Sieć Badawcza Łukasiewicz - Instytut Biopolimerów i Włókien Chemicznych
Powiązania:
https://bibliotekanauki.pl/articles/24200967.pdf  Link otwiera się w nowym oknie
Opis:
Herbal extract-induced metallic nanoparticles have replaced the traditionally synthesized nanoparticles to achieve sustainability in antimicrobial textiles. Silver nanoparticles (NPs) were created by the bio-reducion of silver nitrate with eucalyptus corymbia leaf extract. The bi-lateral activities of herbal extract, like the reduction and capping of silver nanoparticles, have added new dimensions in the bactericidal sector. Silver nanoparticles were characterized by UV-visible spectroscopy, a particle size analyzer, Fourier transform infrared spectroscopy (FTIR), field emission scanning electron microscopy (FESEM), energy dispersive X-ray (EDX) and X-ray diffractometry. In this study these biosynthesized nanoparticles were applied on cotton fabric alone and along with chitosan by the pad-dry-cure method to create antibacterial clothing. Antibacterial efficiency was characterized using the colony counting method (serial dilution method). The treated fabric shows excellent antibacterial efficiency.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The influence of cholesterol precursor : desmosterol : on artificial lipid membranes
Autorzy:
Flasiński, Michał
Wydro, Paweł
Hąc-Wydro, Katarzyna
Olechowska, Karolina
Mach, Marzena
Opis:
The disorders in cholesterol biosynthesis pathway and various diseases manifest in the accumulation of cholesterol precursors in the human tissues and cellular membranes. In this paper the effect of desmosterol--one of cholesterol precursors--on model lipid membranes was studied. The investigations were performed for binary SM/desmo and POPC/desmo and ternary SM/POPC/desmo monolayers. Moreover, the experiments based on the gradual substitution of cholesterol by desmosterol in SM/POPC/chol=1:1:1 system were done. The obtained results allowed one to conclude that desmosterol is of lower domains promoting and stabilizing properties and packs less tightly with the lipids in monolayers. Moreover, desmosterol probably could replace cholesterol in model membranes, but only at its low proportion in the system (2%), however, at a higher degree of cholesterol substitution a significant decrease of the monolayer stability and packing and alterations in the film morphology were detected. The results collected in this work together with those from previous experiments allowed one to analyze the effect of a double bond in the sterol side chain as well as its position in the ring system on membrane activity of the molecule and to verify Bloch hypothesis.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
Tytuł:
Herbal Extract-Induced Silver Nanoparticles for Antibacterial Cotton Fabric
Autorzy:
Singh, Mukesh Kumar
Rajput, Sanjeev Kumar
Shakyawar, Dinesh Babu
Wydawca:
Sciendo
Cytata wydawnicza:
Rajput SK, Singh MK, Shakyawar DB. Herbal Extract-Induced Silver Nanoparticles For Antibacterial Cotton Fabric. Fibres & Textiles in Eastern Europe. Sciendo, 2023;31}(3): 22-29. https://doi.org/10.2478/ftee-2023-0024
Opis:
Herbal extract-induced metallic nanoparticles have replaced the traditionally synthesized nanoparticles to achieve sustainability in antimicrobial textiles. Silver nanoparticles (NPs) were created by the bio-reducion of silver nitrate with eucalyptus corymbia leaf extract. The bi-lateral activities of herbal extract, like the reduction and capping of silver nanoparticles, have added new dimensions in the bactericidal sector. Silver nanoparticles were characterized by UV-visible spectroscopy, a particle size analyzer, Fourier transform infrared spectroscopy (FTIR), field emission scanning electron microscopy (FESEM), energy dispersive X-ray (EDX) and X-ray diffractometry. In this study these biosynthesized nanoparticles were applied on cotton fabric alone and along with chitosan by the pad-dry-cure method to create antibacterial clothing. Antibacterial efficiency was characterized using the colony counting method (serial dilution method). The treated fabric shows excellent antibacterial efficiency.
Dostawca treści:
Repozytorium Centrum Otwartej Nauki
Artykuł

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