Temat: controlled release - Prolib Integro

Skocz do pozycji: 1.

Tytuł:: A multicarotenoid beadlet for human nutrition - proof of concept of in vitro timed release
Autorzy:: Gellenbeck, Kevin
Salter-Venzon, Dawna
Lala, Rajendra
Chavan, Jayanthi
Tematy:: dissolution
carotenoid
bioavailability
controlled release; Pokaż więcej
Wydawca:: Polskie Towarzystwo Biochemiczne
Powiązania:: https://bibliotekanauki.pl/articles/1039766.pdf Link otwiera się w nowym oknie
Opis:: Since the 1980's when the predominate focus of study and use of carotenoids in human nutritional formulations was solely on beta-carotene, there has been a steady increase in research aimed to understand the role of a wide variety of carotenoids in human health. This work has increasingly demonstrated the benefits of a number of carotenoids, and there has been a corresponding increase in the number of carotenoids provided in nutritional supplements (multicarotenoids). Numerous published observations in both human and animal studies suggest significant interaction and competition between various carotenoids during absorption and metabolism, resulting in the inhibition of uptake of one over the other. This competition has the end result of reducing the beneficial effects of the inhibited carotenoid. To limit such competition and maximize carotenoid uptakes, a layered beadlet was designed to release a defined ratio of carotenoids sequentially. Preliminary dissolution testing is presented showing the release profile in simulated digestive conditions of a combination of beta-carotene, alpha carotene, lutein, zeaxanthin, lycopene and astaxanthin derived from natural sources. Comparison is made to an immediate release beadlet formulation using the same combination of carotenoids. These results will be used to guide proof of concept clinical testing for effectiveness in humans.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Ethylcellulose as a coating material in controlled-release fertilizers
Autorzy:: Lubkowski, Krzysztof
Smorowska, Aleksandra
Sawicka, Marta
Wróblewska, Elwira
Dzienisz, Alicja
Kowalska, Małgorzata
Sadłowski, Marcin
Tematy:: mineral fertilizers
controlled release
ethylcellulose; Pokaż więcej
Wydawca:: Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie
Powiązania:: https://bibliotekanauki.pl/articles/778115.pdf Link otwiera się w nowym oknie
Opis:: Ethylcellulose polymer was used as a coating material in the preparation of controlled release fertilizers. The materials have been prepared with the use of an immersion method. The mass ratio of polymer to fertilizer was in the range of 0.165–0.285 and the layer thickness was in the range of 204–244 μm. Mechanical properties of the prepared materials were significantly better in comparison with the initial fertilizer. Measurements of time and the degree of release of mineral components from the obtained materials were determined with a standard method. Ethylcellulose-coated materials have met the requirements of controlled release fertilizers.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Coated NPK Fertilizer Based on Citric Acid-Crosslinked Chitosan/Alginate Encapsulant
Autorzy:: Mesias, Vince St. D.
Agu, Anne Bernadette S.
Benablo, Precious Japheth L.
Chen, Chun-Hu
Penaloza Jr., David P.
Tematy:: controlled release
crosslinking
encapsulation
NPK fertilizer; Pokaż więcej
Wydawca:: Polskie Towarzystwo Inżynierii Ekologicznej
Powiązania:: https://bibliotekanauki.pl/articles/124714.pdf Link otwiera się w nowym oknie
Opis:: A coated nitrogen-phosphorus-potassium (NPK) fertilizer was prepared via crosslinking chitosan and alginate using citric acid. Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), particle size analysis, and zeta potential measurement showed the successful crosslinking, appropriate size, and colloidal stability of the coated NPK fertilizer. The encapsulation capability of the crosslinked chitosan/alginate (Chi/Alg) was studied using fluorescence spectroscopy and NPK analysis. The release behavior studies under various pH conditions showed that Chi/Alg NPK conformed to the standards of controlled release fertilizer with a maximum release rate of 40% for 30 days. The investigation of the release mechanism using Korsemeyer-Peppas mathematical model showed that the release of nutrients is governed by both coating material relaxation and diffusion process.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Three dimensional printing in pharmaceutical and medical practice
Technika druku przestrzennego w praktyce farmaceutycznej i medycznej
Opis:: Three-dimensional printing (3DP) is a method of rapid prototyping, classified to the solid freeform fabrication technologies or an additive printing processes. Due to its advantages such as: precision, flexibility and capability of manufacturing complicated objects in a short time, this technology is applied to science and engineering. The attempts have been made to use 3DP method in pharmaceutical technology to prepare drug delivery devices with complicated shapes, complex inner structures, containing different active substances and excipients. The precisely defined architecture allows a programming of the desired drug release profiles. The three-dimensional printing technique is suitable for manufacturing of matrix or coated systems, multilayer tablets, orodispersible tablets and implants. The other medical applications include the design of surgical procedures or manufacturing of artificial tissues and organs.
Dostawca treści:: Repozytorium Uniwersytetu Jagiellońskiego

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Skocz do pozycji: 5.

Tytuł:: Preparation of micro-encapsulated strawberry fragrance and its application in the aromatic wallpaper
Autorzy:: Xiao, Z.
Zhang, Y.
Zhu, G.
Niu, Y.
Xue, Z.
Zhu, J.
Tematy:: micro-encapsulation
fragrance
wallpaper
controlled release; Pokaż więcej
Wydawca:: Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie
Powiązania:: https://bibliotekanauki.pl/articles/778533.pdf Link otwiera się w nowym oknie
Opis:: Micro-encapsulated strawberry fragrance was successfully prepared with wall materials including maltodextrin, sodium octenylsuccinate and gum Arabic. The micro-capsule was added to wallpaper and aromatic wallpaper with strawberry characteristics was obtained. The particle distribution, surface morphology, chemical structure, thermal property and controlled release performance of micro-encapsulated fragrance and aromatic wallpaper were investigated using laser particle size analyzer, scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-TR), thermal gravity analysis (TGA) and chromatography-mass spectrometer (GC-MS). The results showed that the average diameter of micro-capsule was 2 μm and the particles mainly distributed in the tissues of wallpaper. The result of TGA showed that the micro-capsule had a good stability. Meanwhile, the aromatic wallpaper had strawberry aroma more than 3 months and took on excellent controlled release performance.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 6.

Tytuł:: Modified dibutyrylchitin films as matrices for controlled ibuprofen release
Autorzy:: Mucha, Maria
Michalak, Iwona
Draczyński, Zbigniew
Tematy:: controlled release
dibutyrylchitin
ibuprofen
nanoclay
transdermal systems; Pokaż więcej
Wydawca:: Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Powiązania:: https://bibliotekanauki.pl/articles/1035223.pdf Link otwiera się w nowym oknie
Opis:: In view of ongoing interest in biodegradable polymers, dibutyrylchitin was used as a matrix for controlled release of a model substance. Transdermal systems (films) are presently more commonly used as an alternative to standard forms of drug delivery. The presented results are concerned with the release of ibuprofen from dibutyrylchitin film. The obtained transdermal films were modified by applying a control layer to slow down the release process. The matrices were also modified by adding nanoclay (Nanofil 2). Dibutyrylchitin matrices were tested for swelling and release kinetics using UV-Vis spectrophotometer. The drug kinetics release was studied in phosphorus buffer of pH=5.5 at the temperature of 35˚C. Structural investigations of the obtained matrices were carried out by optical microscopy and FTIR spectrophotometry. An appropriate mathematical model was also fitted to the obtained experimental data
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 7.

Tytuł:: Encapsulation of hydroxycitronellal in β-cyclodextrin and the characteristics of the inclusion complex
Autorzy:: Zhu, Guangyong
Xiao, Zuobing
Zhou, Rujun
Liu, Junhua
Zhu, Guangxu
Tematy:: food additives
encapsulation
aroma
controlled release
flavor; Pokaż więcej
Wydawca:: Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie
Powiązania:: https://bibliotekanauki.pl/articles/2204143.pdf Link otwiera się w nowym oknie
Opis:: Hydroxycitronellal has been widely used in foods, beverages, perfumery and cosmetics. It can also be used to treat anxiety. The major drawbacks regarding the use of hydroxycitronellal are related to water insolubility, volatility, instability, and sensitization. To overcome these concerns, β-cyclodextrin was adopted as wall material to encapsulate hydroxycitronellal in this work. Hydroxycitronellal-β-cyclodextrin inclusion complex was prepared and the product was characterized. The interaction of hydroxycitronellal and β-cyclodextrin, and the assembly of hydroxycitronellal-β-cyclodextrin inclusion complex were investigated by molecular simulation (MM). The results showed that hydroxycitronellal loading capacity was 8.5%. The thermal stability and lastingness of hydroxycitronellal were im-proved by the formation of the inclusion complex. The minimum binding energy was –151.2 kJ/mol. Among the perpendicular, staggered parallel and ideally parallel orientation of the inclusion complexes, the minimum energy value was found for the staggered parallel arrangement. These basic data are useful to understand the interaction between hydroxycitronellal and β-cyclodextrin.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 8.

Tytuł:: The Perspectives on the Application of Biopolymers for a Sustainable Agriculture
Autorzy:: Kończak, Beata
Białowąs, Małgorzata
Tematy:: agriculture
biopolymer
sodium alginate
slow-release fertilizer
controlled-release fertilizer; Pokaż więcej
Wydawca:: Polskie Towarzystwo Inżynierii Ekologicznej
Powiązania:: https://bibliotekanauki.pl/articles/59113833.pdf Link otwiera się w nowym oknie
Opis:: One of the main challenges for modern agriculture is to seek methods for improvement of crop growth and quality which is based on the sustainable agriculture to provide the growing population with access to high-quality food. Controlled-release fertilizers (CRF) and slow-release fertilizers (SRF) are the answer to these challenges, as they constitute an alternative means of achieving higher agronomic efficiency relative to traditional fertilizers. The focus of this paper is to review the changes and trends regarding the CRF/SRF, with a particular focus on biopolymer-coated fertilizers, specifically sodium alginate as both the biopolymer for coating and a soil conditioner. The presented literature review reveals the promising prospects related to the necessity of developing fertilizers with a controlled/slow release of minerals, involving materials that provide the appropriate mineral release rate and which are characterized by properties ensuring a substantial reduction in the negative impact on the natural environment. This finds confirmation in the clear tendency for applying biodegradable materials, particularly originating from natural sources, which may become the appropriate materials used for fertilizer coating when considering the new requirements concerning environmental issues.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 9.

Tytuł:: Polymeric Microcapsules as Carriers of Biological Agents
Mikrokapsuły polimerowe jako nośniki substancji biologicznie czynnych.
Autorzy:: Sowińska, Katarzyna
Opis:: W niniejszej pracy skupiono się na otrzymaniu stabilnych kapsuł polimerowych na ciekłym rdzeniu stabilizowanych przez amfifilowy kopolimer szczepiony, zbadano zdolność enkapsulacji związków hydrofobowych w olejowym rdzeniu oraz ich uwalnianie z wykorzystaniem fluorescencyjnego barwnika czerwieni Nilu. Wykorzystano kapsuły o ciekłym rdzeniu ze względu na szereg zalet w stosunku do ograniczeń stosowania kapsuł na stałym rdzeniu, tj. niskiej wydajności ładowania czynnika aktywnego do pustych kapsułek, możliwości uszkodzenia i niekontrolowanej modyfikacji powłoki kapsułek podczas wytrawiania rdzenia czy też długiego czasu otwierania i zamykania otoczki podczas ładowania.Celem poprawy stabilności uzyskanych kapsuł pokrywano je wielowarstwowymi filmami polimerowymi wykorzystując metodę warstwa po warstwie (ang. Layer by Layer, LbL), która opiera się na naprzemiennej adsorpcji polianionów i polikationów na naładowanej powierzchni. Następnie skorzystano z metody dynamicznego rozpraszania światła (ang. Dynamic Light Scattering, DLS), która posłużyła do charakteryzacji tak otrzymanych kapsuł. Przeprowadzone badania pozwoliły na potwierdzenie zdolności stabilizacji emulsji typu olej w wodzie za pomocą amfifilowego kopolimeru szczepionego, udało się otrzymać stabilne kapsuły zdolne do enkapsulacji hydrofobowych barwników oraz ich przedłużonego uwalniania z olejowego rdzenia.
Polymers are macromolecular compounds that occur both naturally and are produced by chemical synthesis. The present study focuses on receiving a stable capsule core liquid polymer stabilized at the amphiphilic graft copolymer, further investigating the ability of the encapsulation of hydrophobic compounds in the oil core and the release of the fluorescent dye using the Nile red. The liquid core of the capsule were used due to a number of advantages over the restrictions on the use of a solid core capsules, i.e. reduced core removal efficiency, poor charging efficiency of the active agent into empty capsules, the possibility of damage and uncontrolled modification of the coating during etching of the core capsules or long opening and closing the shell during charging. To improve the stability of the capsule covers they were multilayerd with polymer films using a layer-by-layer method (LbL), which is based on alternating adsorption of polyanions and polycations on the charged surface. Then the dynamic light scattering method (DLS) was applied to characterize the so obtained capsules. The studies allowes confirming the ability of stabilization of the emulsion of oil in water using an amphiphilic graft copolymer, both with successfuly obtaining a stable capsules capable of encapsulating the hydrophobic dye with their sustained release of the oil core.
Dostawca treści:: Repozytorium Uniwersytetu Jagiellońskiego

Inne

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Skocz do pozycji: 10.

Tytuł:: Impact of Controlled-Release Fertilizer on Avaibility of Phosphorus, Sulphur, Iron, Copper, Zinc, Manganese and Production of Red Onion (Allium ascalonicum L.)
Autorzy:: Suwardi, Suwardi
Suryaningtyas, Dyah Tjahyandari
Ghofar, Abdul
Rosjidi, Mochamad
Mustafa, Anwar
Saputra, Hens
Tematy:: controlled release fertilizer
food security
micronutrients
red onion; Pokaż więcej
Wydawca:: Polskie Towarzystwo Inżynierii Ekologicznej
Powiązania:: https://bibliotekanauki.pl/articles/59114331.pdf Link otwiera się w nowym oknie
Opis:: Fertilization plays a crucial role in meeting the nutrient requirements of plants to achieve optimal production. The application of controlled-release fertilizer (CRF) on red onion cultivation holds the potential to enhance fertilizer efficiency while reducing water pollution. This study aimed to investigate the impact of CRF application on the availability of essential nutrients of P, S, Fe, Cu, Zn, Mn, and production of red onion (Allium ascalonicum L.). The research was conducted in two stages, an incubation experiment in laboratories and field experiments. The treatments included three types of fertilizers, P1: NPKCaMgS (13-8-10-5-9-2), P2: NPKS (19-12-15-4), and Mutiara: NPK (16-16-16). For the incubation experiment, two fertilizer doses were used: D6 (600 kg/ha), D12 (1200 kg/ha), along with a control group. For the field experiments, four fertilizer doses were employed: D3 (300 kg/ha), D6 (600 kg/ha), D9 (900 kg/ha), D12 (1200 kg/ha), also with a control group. The results indicated that the availability of P, Cu, and Mn increased with a longer incubation period, while the availability of Fe and Zn decreased over time. The availability of S exhibited irregular patterns with an extended incubation period. Notably, the highest onion production was achieved using NPKCaMgS (13-8-10-5-9-2) at a dose of 300 kg/ha.
Dostawca treści:: Biblioteka Nauki

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