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Wyświetlanie 1-10 z 996
Tytuł:
Infection Control in the Post-Antibiotic Era
Autorzy:
Upla, Peter
Ukpanah, Mfonido
Gbadeyan, Femi
Uyi, Gerard
Dauda, Odenye
Tematy:
Infection control
antibiotic resistance
hand hygiene
nosocomial infection
tetratogenic infection
transposons
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Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Powiązania:
https://bibliotekanauki.pl/articles/1114109.pdf  Link otwiera się w nowym oknie
Opis:
Antibiotic resistance by pathogenic microorganisms has become a major clinical and public health problem in the 21st century. Countries across the world are faced with restricted healthcare resources, high demand for modern drugs and increasing antimicrobial resistance. This escalation in antibiotic resistance is attributed to the misuse and over use of antibiotics, poor isolation practices and long hospital stay of patients who then become susceptible to nosocomial infection. The misuse and overuse of antibiotics is now generating resistance to almost all classes. However, it is pertinent to emphasize that even with the pervasive nature of antibiotic resistance worldwide; infections acquired by patients in the hospital must be treated. Thus, this review article proposes some control options and recommendations to protect us against resistant bacterial strains.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Surgical site infection– the authors’ own prospective research
Autorzy:
Neuman, Danuta
Grzebieniak, Zygmunt
Tematy:
surgical site infection
risk factors of postoperative infection
surgical wound infection prophylaxis
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Wydawca:
Index Copernicus International
Powiązania:
https://bibliotekanauki.pl/articles/1395703.pdf  Link otwiera się w nowym oknie
Opis:
Surgical site infection is a common complication in surgery, which increases treatment cost, extends hospitalization time and can lead to septic complications. The aim of the study was analysis of postoperative infections in own material and finding significant risk factors with preserving the obligatory procedures in the clinic. Material and methods. Prospective analysis of 270 consecutively operated patients aged from 18 to 101 was performed with observation of early infection until 7th day postoperatively. Factors judged included: age, sex, BMI, operation type: elective or urgent, physical preparation for surgery, antibiotic prophylaxis, length and type of surgery. Wound observation card was used. Data were analysed statistically (t-Student’s test, chi2 test, U Mann Whitney test and logistic regression analysis). Results. Wound infection was observed in 33 patients (12.22% of the entire group). In 24 (8.88%) it was a superficial infection and in 9 (3.33%) deep infection. Statistically significant risk factors were age, presence of diabetes, operation time and operations on large bowel. The average age of patients with present infection was 61.2. In the group without infection there were 6,3% patients with diabetes and 20.8% in the group with infection. In our study diabetes increased the risk of infection four times. The longer the operation time the higher was the risk of deep infection (without complications 76.2 minutes, superficial 94.9 minutes, deep 148.9 minutes). Operations on large bowel were performed in 11.9%of all study patients. In the group of 33 patients with surgical wound infection, 39.4% had colon surgery, 39.4% of all deep infections and 29.2% of all superficial infections. Conclusions. In own study material significant risk factors of surgical wound infection were: age, presence of diabetes, length of operation, large bowel surgery. In preoperative course risk factors should be identified to perform certain prophylactic procedures to lower the risk of infectious complications.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Research on the possibility of treating streptococcal infections with hyperbaric oxygenation
Autorzy:
Wolański, Władysław
Tematy:
streptococcus
mouse
general infection
local infection
hyperbaric therapy
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Wydawca:
Polskie Towarzystwo Medycyny i Techniki Hiperbarycznej
Powiązania:
https://bibliotekanauki.pl/articles/1375129.pdf  Link otwiera się w nowym oknie
Opis:
The aim of the study was to determine the effect of the application of hyperbaric oxygen therapy on the course of an infection with group A type T-3 hemolytic β streptococcus. Experiments were carried out on Porton white mice and in vitro blood plates. General and local infections with streptococci were induced in animals. The infected animals were treated with hyperbaric oxygenation. The lethal effect of infection was significantly inhibited using hyperbaric oxygenation on the first and second day following the infection.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Immunosuppression during Leishmania donovani infection: a potential target for the development of therapy
Autorzy:
Flora, R.
Aghazadeh-Dibavar, S.
Bandyopadhyay, M.
Dasgupta, S.
Tematy:
immunosuppression
Leishmania donovani
parasite
infection
therapy
leishmanial infection
leishmaniasis
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Wydawca:
Polskie Towarzystwo Parazytologiczne
Powiązania:
https://bibliotekanauki.pl/articles/5556.pdf  Link otwiera się w nowym oknie
Opis:
Dysfunction of T-helper 1 mediated immune responses is a hallmark of the progression of visceral leishmaniosis (VL). Several factors such as altered antigen presentation, and abnormalities in MHC/HLA, antigen processing, and T cell receptor recognition regulate the onset of immunosuppression. Recent investigations on VL patients suggest that susceptibility to visceral leishmaniosis is genetically determined and varies between populations in different geographical locations. Emerging evidence also indicates the importance of the role played by myeloid derived suppressor cells in progressive VL. This study provides a mechanistic view of means to target the signaling mechanisms of immunosuppression to determine potential therapeutic interventions.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The level of knowledge of, attitude toward and emphasis given to HBV and HCV infections among healthcare professionals: Data from a tertiary hospital in Turkey
Autorzy:
Cekin, Ayhan H.
Cekin, Yesim
Ozdemir, Aygul
Tematy:
knowledge
attitude
HBV infection
HCV infection
healthcare workers
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Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Powiązania:
https://bibliotekanauki.pl/articles/2179797.pdf  Link otwiera się w nowym oknie
Opis:
Objectives: To evaluate the level of knowledge of, to investigate the attitudes toward, and to determine the emphasis given to the national prevalence of HBV/HCV infections among healthcare professionals. Materials and Methods: A total of 206 healthcare professionals (mean (SD) age: 37.0 (6.3) years; 86.9% – females) including medical laboratory technicians (N = 54) and nurses (N = 152) employed in the Antalya Training and Research Hospital, Antalya, Turkey. Laboratory (N = 53), operating room (N = 41) and in-patient clinic (N = 112) staff were included in this descriptive study. A 33-questionnaire composed of questions related to their level of knowledge and attitudes toward HBV/HCV infections, the sources of their knowledge of HBV/HCV infections and the emphasis given to the national and global importance of the diseases was administered via a face–to-face interview method with each subject; participation was volunteer based. Results: The participants working in the in-patient clinic (18.0 (3.2)) had the highest mean (SD) knowledge level compared to the laboratory (16.4 (3.1), p < 0.05) and operating room (17.0 (2.8), p < 0.05) staff. The participants from the in-patient clinic (44.6%) had a more advanced level of knowledge compared to the participants working in the laboratory (27.8%, p < 0.05) and the operating room (30.0%, p < 0.05). Most of the subjects (60.7%) had education concerning HBV/HCV infections in the past. There was no signifi cant difference between the hospital units in terms of the attitudes of healthcare workers (HCWs) toward HBV/HCV infections and the level of education concerning them. Conclusions: Our fi ndings revealed a moderate level of knowledge in most HCWs, regardless of their exposure to risk. While the highest knowledge scores and vaccination rates were noted among the in-patient clinic staff, there was no signifi cant difference between the hospital units in terms of the attitudes of HCWs towards a patient or a colleague with an HBV/HCV infection.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Descending necrotizing mediastinitis in patients with deep neck phlegmon due to oropharyngeal infection
Autorzy:
Sheiko, Vladymyr
Nebaba, Sergey
Loburets, Andriy
Cherkun, Oleksii
Ohanezian, Aikanush
Levytskyi, Heorhii
Tematy:
deep neck infection
descending necrotizing mediastinitis
oropharyngeal infection
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Wydawca:
Index Copernicus International
Powiązania:
https://bibliotekanauki.pl/articles/58907777.pdf  Link otwiera się w nowym oknie
Opis:
Introduction: Among the diseases leading to deep neck infection (DNI) and descending necrotizing mediastinitis (DNM), odontogenic causes are the most prevalent, accounting for 40–70% of cases. Tonsillo-pharyngeal causes follow at 16–30%, while other etiologies do not exceed 6%. Materials and methods: A retrospective analysis was conducted, examining the clinical course, diagnostic measures, and treatment strategies of 139 patients with DNI due to oropharyngeal inflammatory diseases. These patients were treated at the Poltava Regional Clinical Hospital from 2012 to 2023. Based on the primary source of infectious/purulent inflammation, patients were divided into two groups. Group I included 25 patients with tonsillo-pharyngeal origin of DNI; Group II consisted of 114 patients with dental origin of DNI. The study assessed the course, diagnosis, and treatment outcomes based on the parameters of gender, age, etiological factor, underlying pathology, disease duration before hospitalization, initiation of antibiotic therapy, type of DNM based on spread pattern, causative agent, severity of condition upon admission, signs of sepsis, type of surgical intervention, postoperative complications, duration of treatment in the intensive care unit, overall hospitalization duration, and mortality. Results: Oropharyngeal infection is the predominant cause of DNI and DNM. Notably, odontogenic DNI is more frequently observed than tonsillopharyngeal DNI (82.0% vs. 18.0%). Its progression is characterized by lower mortality (13.2% vs. 24.0%) and a reduced risk of DNM onset (7.0% vs. 44.0%). However, odontogenic DNM is more often associated with adverse outcomes (50.0% vs. 9.1%). Conclusions: Thus, frequency and severity of DNM in patients with DNI depends on the etiology of the disease, but the adverse consequences of treatment are largely influenced by weak concomitant pathology and sepsis during hospitalization.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of different contents of proteins and vitamin B2 in the feed on the prevalence and infection intensity of Ascaridia galli in chickens
Autorzy:
Jabłonowski, Z.
Sudoł, K.
Dziekońska-Rynko, J.
Dzika, E.
Tematy:
parasite
infection prevalence
Ascaridia galli
content
vitamin B2
protein
parasitic infection
infection intensity
chicken
feed
Pokaż więcej
Wydawca:
Polskie Towarzystwo Parazytologiczne
Powiązania:
https://bibliotekanauki.pl/articles/2147829.pdf  Link otwiera się w nowym oknie
Opis:
A group of 10-day-old chickens was experimentally infected with a dose of 500 infective eggs of Ascaridia galli (Schrank, 1788) (Nematoda). Forty-nine days post infection the chickens were necropsied and the infection intensily and prevalence were determined. The group maintained on the feed containing 11% of protein showed higher infection intensity and prevalence compared to the chickens fed a diet containing 19% of protein. The addition of vitamin B₂ to the feed containing 11% protein resulted in lower intensity and prevalence of the infection. In both series of experiments no effect of Zn-bacitracin or vitamin B₂ on infection intensity or prevalence was observed for chickens fed feed containing 19% of protein.
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-10 z 996

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