- Tytuł:
- The viscoelasticity, anisotropy and location-dependence of mechanical properties of rabbit iris investigated using uniaxial tensile tests
- Autorzy:
-
Li, Tan
Qin, Xiao
Liu, Zhicheng
Zhang, Haixia
Li, Lin - Tematy:
-
iris
uniaxial tensile test
stress relaxation
anisotropic mechanical property
location-dependence - Pokaż więcej
- Wydawca:
- Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
- Powiązania:
- https://bibliotekanauki.pl/articles/55622201.pdf Link otwiera się w nowym oknie
- Opis:
- Abnormal iris mechanical properties have been considered to be an important cause of pupillary-block and angle-closure glaucoma. In this research, viscoelasticity, anisotropy and location-dependence of mechanical properties of rabbit iris were investigated using uniaxial tensile test. Methods: Iris strips were taken along three directions: inner-circumferential direction (ICD), outer-circumferential direction (OCD) and radial direction (RD), respectively. Quasi-static tensile tests and stress–relaxation tests were applied on the iris strips. Then, the stress–stretch data was fitted with third order Ogden model; the stress–relaxation data was fitted with the third order Prony series model. Through comparing the tangent modulus and relaxation limit of the strips from different directions and locations, the viscoelasticity, anisotropy and location-dependence of mechanical properties of rabbit iris were explored. Results: The tangent moduli of iris at the stretch of 1.05 along ICD, OCD, and RD were 3.2 ± 1.4 kPa, 4.2 ± 2.6 kPa, 1.5 ± 0.8 kPa, respectively. Iris strips in ICD and OCD were found to have almost the same stress–relaxation behavior, and both relaxed slower than iris strips in RD. Conclusions: The mechanical properties of the iris were typically nonlinear, viscoelastic, anisotropic and location-dependent. The stress growth rate of the circumferential direction iris strip is significantly lower than that of RD and the stress–relaxation rate is significantly higher than that of the RD. That is, the iris is more prone to deformation in RD and the stress–retention ability after deformation in RD is weak, which is consistent with the fact that the iris bombe more likely happens in RD in vivo. The results of this study may also help us to establish a more accurate finite element model to simulate the flow field of humor aqueous and find the key factor of pupillary-block.
- Dostawca treści:
- Biblioteka Nauki
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