Temat: methanolic extract - Prolib Integro

Skocz do pozycji: 1.

Tytuł:: DIPSACUS FULLONUM L. LEAVES AND ROOTS - IDENTIFICATION OF THE COMPONENTS OF THE ESSENTIAL OILS AND ALPHA-AMYLASE INHIBITORY ACTIVITIES OF METHANOLIC EXTRACTS
Autorzy:: Witkowska-Banaszczak, Ewa
Tematy:: essential oil composition
methanolic extract
alpha-amylase inhibition; Pokaż więcej
Wydawca:: Polskie Towarzystwo Farmaceutyczne
Powiązania:: https://bibliotekanauki.pl/articles/895320.pdf Link otwiera się w nowym oknie
Opis:: Abstract: Dipsacus fullonum L. syn. D. sylvestris is a biennial plant from the Dipsacaceae family. It grows in Europe, North Africa and Asia Minor. It has been used in folk medicine mainly to treat Lyme disease. This study was undertaken to identify and compare the components of the essential oils from dried and fresh roots, which are usually applied as medicinal agents, as well as those of the essential oils from dried and fresh leaves, used less frequently. The essential oils from the Dipsacus fullonum leaves and roots were analysed by the GC and GC-MS analysis. 18 components were identified in the essential oil from the fresh leaves, whereas 37 were recognised in the oil from the dried leaves; 10 components were identified in the essential oil from the fresh roots and 40 in that from the dried roots. Phytol was the main component in the essential oil from the leaves, whereas n-hexadecanoic acid was predominant in the roots. The α -amylase inhibition has been proven for methanolic extracts of D. fullonum leaves and roots. The strongest activity was demonstrated by the extract from fresh leaves of D. fullonum and showed an effect about one hundred times weaker than acarbose.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Effect of the solvent on the extraction of polyphenols from distillery stillage and on their antioxidant activity
Autorzy:: Mikucka, Wioleta
Zielińska, Magdalena
Tematy:: DPPH assay
Folin-Ciocalteu
phenolic content
methanolic extract
ethanolic extract; Pokaż więcej
Wydawca:: Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
Powiązania:: https://bibliotekanauki.pl/articles/1830630.pdf Link otwiera się w nowym oknie
Opis:: The increase in the costs of storage and disposal of post-production residues has resulted in the search for new directions for their recycling, which is closely related to the necessity of protecting the natural environment and promoting a circular economy. Moreover, the apparent interest shown by the food market in raw materials with high antioxidant activity implies an increasing use of by-products. The objective of the study was to determine the effect of the type and concentration of the solvent on the efficiency of extracting polyphenols from distillery stillage as well as their antioxidant activity by using several solvents: methanol:water (70:30 v/v), methanol:water (100:0 v/v), ethanol:water (70:30 v/v) or ethanol:water (100:0 v/v). The DPPH radical method was used to determine the antioxidant activity of the obtained extracts. The normalised variable (NV) and statistical measure (MS) were determined, based on which the effectiveness of the solvents was evaluated. The highest polyphenolic content and the antioxidant activity were obtained by using ethanol:water (70:30 v/v) as a solvent in the extraction of polyphenolic compounds from distillery stillage.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Analysis of indole compounds in "Armillaria mellea" fruiting bodies
Autorzy:: Ekiert, Halina
Maślanka, Anna
Muszyńska, Bożena
Sułkowska-Ziaja, Katarzyna
Opis:: A TLC method with densitometric detection for identification and quantitation of indole compounds in methanolic extracts of fruiting bodies of Armillaria mellea (Vahl.) P. Kumm. (Basidiomycota) ñ Honey mushroom has been developed. The TLC method with densitometric detection was validated for determination of tryptamine and serotonin contents. The use of this chromatographic-densitometric method for analysis of extracts allowed for a precise, easy and quick determination of the compounds under study. We identified three physiologically active indole compounds: tryptamine, L- tryptophan and serotonin. This analysis demonstrated the highest contents of L-tryptophan (4.467 mg/100 g d.w.). The contents of tryptamine were comparable with the contents of serotonin and amounted to: 2.740 and 2.207 mg/100 g d. w.
Dostawca treści:: Repozytorium Uniwersytetu Jagiellońskiego

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Skocz do pozycji: 4.

Tytuł:: Berberine from Argemone mexicana L exhibits a broadspectrum antibacterial activity
Autorzy:: More, Nilesh
Kharat, Kiran
Kharat, Arun
Tematy:: antibacterial potentiality
Argemone mexicana
aqueous
methanolic extract
HPLC
NMR and phytochemical analysis; Pokaż więcej
Wydawca:: Polskie Towarzystwo Biochemiczne
Powiązania:: https://bibliotekanauki.pl/articles/1038553.pdf Link otwiera się w nowym oknie
Opis:: The Argemone mexicana L, commonly found on desolate land in the Marathwada region of Maharashtra state, India, has been used for treating oral cavity infections. We sought to investigate the antimicrobial potential of A. mexicana L. In this study, cold aqueous and methanolic extracts were prepared from the A. mexicana L leaves. These extracts were tested for their antibacterial activities against selected bacterial isolates. The antibacterial activity and MICs were tested using the agar well diffusion method and broth dilution method, respectively. The cold aqueous and methanolic extracts of A. mexicana L leaves inhibited growth of clinical isolates of Staphylococcus aureus, Bacillus cereus, Escherichia coli and Pseudomonas aeruginosa.The antibacterial potentiality of A. mexicana L extracts was compared with Streptomycin - the reference antibiotic used in this study. The active ingredient of antibacterial potentiality within the A. mexicana L extract was purified and characterized by TLC, HPLC and NMR analysis. Structural elucidation of Berberine and its bioactivity both, from the A. mexicana L and commercial preparation, is investigated.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 5.

Tytuł:: Preliminary study on the impact of methanolic extract of Elephantopus scaber Linn. on hair growth promoting effect in rats
Wstępne badanie wpływu wyciągu metanolowego z Elephantopus scaber Linn. na proces wspomagania wzrostu owłosienia u szczurów
Autorzy:: Sahoo, H.B.
Sagar, R.
Bhattamisra, S.K.
Bhaiji, A.
Tematy:: methanolic extract
Elephantopus scaber
hair growth
promoting effect
rat
hair loss
baldness zob.alopecia
alopecia; Pokaż więcej
Wydawca:: Instytut Włókien Naturalnych i Roślin Zielarskich
Powiązania:: https://bibliotekanauki.pl/articles/72781.pdf Link otwiera się w nowym oknie
Opis:: Methanolic extract of Elephantopus scaber leaves was investigated for its role in hair growth in experimental rats. The 2% and 5% solution of prepared formulation using methanolic extract was studied for hair growth on wistar rats for 30 days. Minoxidil (2% solution) was taken as a reference standard. The prepared hair oil formulation of methanolic extract significantly (p<0.01) potentiated the hair growth initiation and completion time with dosedependent improvement in skin biopsy, hair length and hair weight. In vitro hair follicles development study showed the significant (p<0.05) improvement in the initiation of new hair follicles. Above mentioned results indicated that the methanolic extract of E. scaber rendered significant hair growth promotive effect.
Badano wpływ wyciągu metanolowego z liści Elephantopus scaber na wzrost włosów u szczurów laboratoryjnych. Przez 30 dni badano wzrost włosów u szczurów Wistar po podaniu 2% i 5% preparatu sporządzonego z użyciem ekstraktu metanolowego. Substancją kontrolną był minoksidil (roztwór 2 %). Preparat z ekstraktu metanolowego przygotowany na bazie oleju istotnie (p<0,01) zwiększał inicjację wzrostu włosów i przyspieszał jego zakończenie. Podczas biopsji odnotowano też zależną od dawki poprawę stanu skóry, długości włosów i zwiększenie masy włosów. Podczas badaniu in vitro wykazano istotną (p<0,05) poprawę tworzenia się nowych mieszków włosowych. Powyższe wyniki wskazują, że wyciąg metanolowy z E. scaber może istotnie zwiększać porost włosów.
Dostawca treści:: Biblioteka Nauki

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Tytuł:: Evaluation of antiepileptic activity of methanolic leaves extract of Tragia involucrata Linn. in mice
Autorzy:: Varma, G.G.
Mathai, B.K.
Das, K.
Gowda, G.
Rammohan, S.
Einstein, J.W.
Tematy:: antiepileptic drug
antiepileptic activity
methanolic extract
leaf
plant extract
Tragia involucrata
Indian stinging nettle
mice
mouse
anticonvulsant action
pentylenetetrazol
picrotoxin; Pokaż więcej
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Powiązania:: https://bibliotekanauki.pl/articles/11927.pdf Link otwiera się w nowym oknie
Opis:: The present investigation was aimed to study an antiepileptic activity of methanolic extract of Tragia involucrata Linn in mice. In vivo screening models like maximal electroshock-induced convulsion (MES), pentylenetetrazole (PTZ) and picrotoxin (PTX) induced models are used to evaluate the antiepileptic effects of the extracts. The biochemical estimation was done by measuring the lipid peroxidation and reduced glutathione (GSH). In the MES induced convulsion, methanolic extract of Tragia involucrata (METI) at high dose (800 mg/kg body weight), showed high significant inhibition on tonic hind limb extension (THLE, 6.83 ±0.30***) and decrease in duration of stupor period (108.7 ±6.53***). In PTZ and PTX induced model METI (400 mg/kg and 800 mg/kg) showed significant delay on the onset of convulsions, decreased duration of convulsion and reduced mortality significantly. It also showed significant decrease in brain MDA level in lipid peroxidation profile, and increase in the brain glutathione levels in mice against PTZ induced convulsion. The results confirmed that Tragia involucrata Linn possesses dose dependent antiepileptic activity.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 7.

Tytuł:: Effect of heating on antioxidative activity of rapeseed and evening primrose extracts
Autorzy:: Zadernowski, R.
Nowak-Polakowska, H.
Konopka, I.
Tematy:: evening primrose
Oenothera biennis
heating
food technology
methanolic extract
natural antioxidant
plant oil
polyphenol
antioxidant activity
phenolic acid
plant
rapeseed; Pokaż więcej
Wydawca:: Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk w Olsztynie
Powiązania:: https://bibliotekanauki.pl/articles/1372684.pdf Link otwiera się w nowym oknie
Opis:: The composition and effect of heating (60°-110°C) on antioxidative activity in plant oil of rapeseed (RE) and evening primrose (EPE) methanolic extracts were studied. Different phenolics characterized the extracts. The EPE contained about 10-fold higher amount of phenolics (862.2 g/kg extract) than RE; flavanols (683.8 g/kg) and proanthocyanidins (760.1 g/kg) prevailed in the former and phenolic acid derivatives in the latter. The phenolic compounds of both extracts differed with the fenolic acids composition. Sinapic acid prevailed in rapeseed phenolics and protocatechic and gentisic acids in evening primrose phenolics. Both extracts had generally similar antioxidative activity in the temperature ranging from 60°C to 80°C with the oil peroxide values from 3.5 mmol O/kg to 5.0 mmol O/kg compared to the range of 6.0-7.0 mmol O/kg in control oils. The temperatures above 80°C decreased the antioxidative activity of both extracts and even made them to be prooxidative.
Badano skład i wpływ temperatury (60-110°C) na właściwości przeciwutleniające ekstraktów metanolowych nasion rzepaku i wiesiołka. Stwierdzono, że olej tych nasion zawierał tokoferole, głównie α- i y-, w ilości 0,65 g/kg (rzepak) i 0,45 g/kg (wiesiołek) (tab. 1), a ekstrakty metanolowe nasion charakteryzowały się różnymi formami związków fenolowych. W porównaniu z ekstraktem rzepakowym, ekstrakt wiesiołka zawierał około 10-krotnie więcej związków fenolowych, wśród których dominowały flawanole i proantocyjanidyny (tab. 2). Kwasy fenolowe i ich pochodne dominowały w ekstrakcie rzepakowym. Związki fenolowe ekstraktów różniły się składem kwasów fenolowych (rys. 1). Ekstrakty metanolowe obu nasion wykazywały się generalnie taką samą aktywnością przeciwutleniającą (rys. 2). W temperaturze powyżej 80°C aktywność przeciwutleniająca ekstraktów zanikała lub nawet obserwowano przyśpieszenie procesu utleniania oleju roślinnego.
Dostawca treści:: Biblioteka Nauki

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Tytuł:: Effects of Artemisia annua methanolic extract on the enzymatic components of intermediary metabolism and the antioxidant system of Pseudococcus viburni Signoret
Autorzy:: Ramzi, S.
Seraji, A.
Gonbad, R.A.
Mirhaghparast, K.
Mojib-Haghghadam, Z.
Tematy:: Artemisia annua
methanolic extract
enzymatic component
intermediary metabolism
antioxidant system
Pseudococcus viburni
mealybug
obscure mealybug
tuber mealybug zob.obscure mealybug
plant pest; Pokaż więcej
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Powiązania:: https://bibliotekanauki.pl/articles/65893.pdf Link otwiera się w nowym oknie
Opis:: Toxicity and physiological alterations were determined in Pseudococcus viburni nymphs treated with Artemisia annua methanolic extract. The leaf dipping bioassay showed LC50 values of 0.287% and 0.194% 24 and 48 hours post-exposure. Activities of general esterases were significantly higher in the control nymphs than in those which had been treated except for the 48 h time interval using α-naphtyl acetate. The activity of glutathione S-transferase using CDNB (1-chloro-2,4-dinitrobenzene) in the control nymphs, was significantly higher than in the control at both time intervals while no significant difference was observed after 24 h in addition to the higher enzymatic activity in the treated nymphs after 48 h. All three aminotransferases were significantly more active in the control nymphs except for time intervals of 24 h for γ-glutamyl transferase and 48 h for alanine aminotransferase. Higher activities of lactate dehydrogenase, acid- and alkaline phosphatase were found in the control nymphs than in treated nymphs for all time intervals. Activities of the enzymes involved in the antioxidant system including catalase, peroxidase, superoxide dismutase, ascorbate peroxidase and glucose-6-phosphate dehydrogenase was increased in the treated nymphs compared to the control. Results of the current study demonstrated toxic effects of A. annua methanolic extract on P. viburni nymphs causing mortality and physiological turbulences.
Dostawca treści:: Biblioteka Nauki

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