Temat: phytochemical - Prolib Integro

Skocz do pozycji: 1.

Tytuł:: Phytochemical studies on Achyranthes aspera
Autorzy:: Abhaykumar, Kamble
Tematy:: Achyranthes aspera
phytochemical
solvents; Pokaż więcej
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Powiązania:: https://bibliotekanauki.pl/articles/1177749.pdf Link otwiera się w nowym oknie
Opis:: Phytochemical analysis was carried out on the plant Achyranthes aspera which revealed the presence of medicinally important bioactive compounds. The presence of phytochemical compounds in the plant Achyranthes aspera was evaluated in root using different solvents such as Petroleum ether, Chloroform, Methanol In the present study, the preliminary phytochemical screening of leaf and flower extracts of Achyranthes aspera showed the presence of phytochemicals such as alkaloids, carbohydrates, flavonoids, proteins, aminoacids, tannins, phenols, steroids, glycosides and saponins.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Evaluation of phytochemical composition and in vitro antioxidant potential of Cyathea latebrosa leaves
Autorzy:: Ikpa, Chinyere B. C.
Maduka, Tochukwu D. O.
Ikpa, Chinomnso Uzoamaka
Tematy:: Characterization
Cyathea latebrosa
GC/MS analysis
Phytochemical
Treatment
antioxidant
in vitro
phytochemical composition; Pokaż więcej
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Powiązania:: https://bibliotekanauki.pl/articles/1193436.pdf Link otwiera się w nowym oknie
Opis:: Phytochemicals and antioxidant potentials of chloroform extract of leaves of Cyathea latebrosa have been investigated. The metabolites detected are Carbohydrates, starch, glycosides, saponins, alkaloids, tannins, flavonoids, sterols, terpenes, and polyuronides. Quantitative Phytochemical analysis gave alkaloid (0.08×102 ±0.02), saponins (0.16×102 ±0.02), tannin (0.11×102 ±0.01), flavonoid (0.16×102 ±0.01), and phenol (0.18×102 ±0.01). FT-IR (KBr) cm-1 analysis showed -NH-(3433.41 weak), -OH- (3851.01 sharp), -C-F (1408.8 strong) –SO-(1101.39) and Ar (1646.3 weak), GC/MS characterization revealed the extract contained [2-Aziridinylethyl]amine (70.7%), Benzeneethamine, 3-fluoro-β,5-dihydroxy-N-methyl (14.0%), N-Methyltaurine (10.7%) and (R)-(-)-2-Amino-1-propanol (3.15%). The presence of these compounds exposed the leaves as a potential remedy for alleviated cold, cancer, malaria and to regulate immune functions. At 400 µg/ml concentration the extract and ascorbic acid produced 54.34% and 96.02% antioxidant activity respectively. The FRAP values were significantly (p < 0.05) low than the value of ascorbic acid (2µ M). The plant extracts showed low antioxidant potential even on higher concentrations when compared to reference standard ascorbic acid.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Phytochemical and Antifungal Activity of Leaf Extracts of Corchorus olitorius and Gongronema latifolium on Fungi Associated with Post-Harvest Deterioration of Maize (Zea mays) Seeds in Oban Community, Nigeria
Autorzy:: Akwaji, P. I.
Umana, E. J.
Okon, E. I.
Tematy:: phytochemical
antifungal
extracts
maize
fungi; Pokaż więcej
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Powiązania:: https://bibliotekanauki.pl/articles/1182869.pdf Link otwiera się w nowym oknie
Opis:: This study was carried out to investigate the fungal pathogens associated with post-harvest deterioration of maize seeds in storage in Oban community, Cross River State, Nigeria, determine the effect of the pathogens on the nutritional content of the maize seeds through biochemical analysis as well as evaluate the phytochemical contents and antifungal activity of ethanolic leaf extracts of Corchorus olitorius and Gongronema latifolium in controlling the isolated fungi in vitro. The fungal pathogens isolated as the causative agents of post-harvest deterioration of maize seeds in this study were Penicillium sp., Fusarium sp., Aspergillus sp., and Rhizopus stolonifer. The result of biochemical analysis of fungal infected and non-infected maize seeds carried out showed a significant increase (P ≤ 0.05) in the moisture content of the fungal infected maize seeds as compared to healthy ones (control), while there was a significant decrease (P ≤ 0.05) in the crude fibre, fat, ash, protein and carbohydrate contents of the fungal infected maize seeds as compared to the healthy ones (control). For the in vitro antifungal assay, various concentrations of the extracts ranging from 20g/200ml, 40g/200 ml, 60g/200 ml, 80g/200 ml and 100g/200 ml were separately added to PDA media. Results shows that at 60g/200 ml and 80g/200 ml and 100g/200 ml concentrations, ethanolic leaf extracts of C. olitorius completely inhibited the radial growth of Penicillium sp., Fusarium sp., Aspergillus sp., and R. stolonifer after seven days observation period while those of ethanolic extracts of G. latifolium completely inhibited the redial growth of the fungal pathogens at 40g/200 ml, 60g/200 ml, 80g/200 ml and 100g/200 ml concentrations. Results, however, shows that the extracts had a significant effect (P ≤ 0.05) on the radial growth of the fungal pathogens at all the different concentrations tested as compared with the control. Phytochemical screening of the extracts revealed the presence of cardiac glycosides, reducing sugars, flavonoids, saponnins, tannins, hydocyanin, and anthraquinones with traces of alkaloids.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Phytochemical Study of Selected Medicinal plant, Solanum Nigrum, the Algerian Desert
Autorzy:: Djaafar, Z.
Ridha, O. M.
Tematy:: Medicinal plants
Solamun Nigrum
Phytochemical analysis; Pokaż więcej
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Powiązania:: https://bibliotekanauki.pl/articles/412362.pdf Link otwiera się w nowym oknie
Opis:: Solanum Nigrum plant contains many compounds of High utility, such as: alkaloids, saponin, and others. Through this study in the field of plant chemistry that we can know all the components of the various parts (leaves, twigs, flowers, fruits and roots) of the plant Solanum Nigrum, and enhance the classification of the operations during the disclosure of the components of the plant and contents of secondary metabolism and some of which adopted the newly particularly alkaloids and terpenes as genetic indicators.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 5.

Tytuł:: Phytochemical Screening, Antioxidant and Antimicrobial Activities of Indoneesiella echioides (L.) Nees Leaves
Autorzy:: Elaiyaraja, A.
Chandramohan, G.
Mariajancyrani, J.
Jayabharathi, G.
Tematy:: Antimicrobial activity
Antioxidant activity
Indoneesiella echioides
Phytochemical screenings; Pokaż więcej
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Powiązania:: https://bibliotekanauki.pl/articles/1193940.pdf Link otwiera się w nowym oknie
Opis:: Indoneesiella echioides (or) Andrographis echioides (L) Nees is an important herb widely distributed in south India. This is commonly known as False Water willow. Indoneesiella echioides (L) Nees is a traditional Indian medicine; the whole plant is highly medicinal value such as the leaf juice of this plant is used to cure fever. The plant was extracted using n-hexane, chloroform, ethyl acetate, acetone, butanol, ethanol and methanol. The present study was to be determined the preliminary phytochemical screening, antioxidant and antimicrobial activities of Indoneesiella echioides (L) Nees leaves.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 6.

Tytuł:: Aqueous Extracts of Ginger (Zingiber officinale Roscoe) and Garlic (Allium satium L.) Bulbs: Phytochemical Screening and In vivo Antitrypanosomal Effect
Autorzy:: Adesola, Ridwan Olamilekan
Ogbole, Esther
Itodo, Akogmu Emmanuel
Salami, Oyiza
Abdulazeez, Modinat Dasola
Tematy:: Ginger
Garlic
Parasitaemia
Phytochemical screening
Trypanosoma brucei brucei; Pokaż więcej
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Powiązania:: https://bibliotekanauki.pl/articles/1839427.pdf Link otwiera się w nowym oknie
Opis:: Aims: To evaluate the phytoconstituent and antitrypanosomal effects of aqueous extracts of Ginger and Garlic bulbs in mice experimentally infected with Trypanosoma brucei brucei. Design: A total of 30 adult male mice (weighing 25-40 g) were randomly grouped into six groups (I, II, III, IV, V, and VI) of 5 animals each. Five Groups (II-VI) were intraperitoneally injected with T. brucei brucei (5×105 cells/ml). Methods and Material: Aqueous extract of ginger and garlic bulbs were obtained using the procedure described by Wabo Pone and the extracts were subjected to phytochemical screening using the standard screening method of Silva. Also, each mice was inoculated with 0.1 ml of blood containing approximately 5×105 cells/ml as described by Herbert and Lumsden. Finally, the aqueous extracts were tested on the inoculated mice. Statistical analysis used: Data obtained were expressed as mean ± standard error of the mean (SEM), and subjected to one-way analysis of variance (ANOVA), SPSS 17.0 statistical software. p<0.05 was considered significant. Results: The aqueous extracts increased the survival time, packed cell volume, rectal temperature, and body weight (Ginger extract only) of mice infected with Trypanosoma brucei brucei. Phytochemical analysis revealed alkaloids, steroids, cardiac glycosides, phenol, and saponins in both Ginger and Garlic. Conclusions: Aqueous extracts of Ginger and Garlic bulbs do not have an anti-trypanosomal effect on Trypanosoma brucei brucei. Consequently, geographical location and time of collection of plants are factors that accept therapeutic on ginger and garlic on tryps and should be considered when testing the plants' efficacy on Trypanosoma brucei brucei.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 7.

Tytuł:: Possible Rhodiola kirilowii use in modern phytotherapy
Możliwości wykorzystania różeńca Kiryłowa (Rhodiola kirilowii) w nowoczesnej fitoterapii
Autorzy:: Furmanowa, Mirosawa
Buchwald, Waldemar
Krajewska-Patan, Anna
Mielcarek, Sebastian
Czerny, Bogusław
Gryszczyńska, Agnieszka
Mrozikiewicz, Przemysław
Mikołajczak, Przemysław Ł
Wydawca:: Borgis
Opis:: Rhodiola kirilowii (Regel) Maxim (Crasssulaceae family) is a plant used in traditional East Asian medicine, mainly in China, to prevent damages due to hypoxic environment of high altitude. The authors present - on the basis of own investigations and wide review of the literature - the present status of phytochemical investigations carried out on R. kirilowii plant. The interesting perspectives of medicinal use of extracts from R. kirilowii are also presented.
Agnieszka Gryszczyńska
Dostawca treści:: Repozytorium Centrum Otwartej Nauki

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Skocz do pozycji: 8.

Tytuł:: Phytochemical Screening and Antimicrobial Activity of Ethanol and Methanol Extracts of Lantana camara Leaf
Autorzy:: Ezebo, R. O.
Okonkwo, C. C.
Ozoh, C. N.
Nwankwo, C. A.
Nwafor, E. C.
Esimai, B. G.
Achonye, C. C.
Obienyem, J. N.
Tematy:: Phytochemical
Antimicrobial
Activity
Ethanol
Methanol
Lantana camara
leaf; Pokaż więcej
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Powiązania:: https://bibliotekanauki.pl/articles/1839418.pdf Link otwiera się w nowym oknie
Opis:: This study investigated the phytochemical composition and antimicrobial activities of ethanol and methanol leaf extracts of Lantana camara Linn against some clinical pathogens. The ethanol and methanol extracts were obtained by soaking each of the powdered leaf in each solvent. The soaked powdered leaf was allowed to stand for four days at room temperature and later filtered using Whatman filter paper. The filtrate was further concentrated using rotary evaporator and then freeze-dried. The minimum inhibitory concentration (MIC) of the ethanol and methanol leaf extracts was carried out using agar well diffusion method. The phytochemical analysis was done using standard techniques. Data were analysed using Analysis of Variance (ANOVA) to test for significance. Means were separated using Duncan’s Multiple Range Test (DMRT). The results of the antimicrobial activity revealed that V. cholerae was the most susceptible while E. coli was the most resistant to plant extracts. The phytochemicals present in the plant leaf had antimicrobial properties and may serve as a good substitute for resistant human pathogens.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 9.

Tytuł:: Phytochemical composition and antibacterial activity of ethanolic extract from trunk of Rothmannia wittii (Craib) Bremek. (Rubiaceae) newly found in Vietnam
Autorzy:: Van, H.T.
Nguyen, T.T.
Ton, H.T.T.
Dinh, K.T.T.
Le, V.S.
Pham, T.V.
Tran, G.B.
Tematy:: Rothmannia wittii
extract
phytochemical composition
antibacterial activity
LC-MS; Pokaż więcej
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Powiązania:: https://bibliotekanauki.pl/articles/2096309.pdf Link otwiera się w nowym oknie
Opis:: Rothmannia wittii, which is found in Binh Chau-Phuoc Buu Nature Reserve, Bung Rieng ward, Xuyen Moc District, Ba Ria-Vung Tau Province, Vietnam, is a rare species of Rubiaceae family. The present study aimed to determine the phytochemical composition and antimicrobial activity of the ethanolic extract of the R. wittii trunk. A total of 10 compounds were identified by liquid chromatography-mass spectrophotometry (LC-MS), including 1) benzene, 1-(1,5-dimethyl-4- hexenyl)-4-methyl, 2) diphenylsulfone, 3) 6β-hydroxy-10-O-acetylgenipin, 4) cinnamyl-cinnamate, 5) genipin, 6) megastigmatrienone, 7) ethyl p-methoxy-trans-cinnamate, 8) rothalazepane, 9) 1,3,6-trimethylpyrano[2,3-d ]imidazole-2,5(1H,3H)-dione, and 10) shanzhiol. The extract also exhibited an antibacterial activity against six bacterial strains: Bacillus cereus, Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, Salmonella typhimurium and Salmonella enteritidis, as determined via disk diffusion agar method.
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 10.

Tytuł:: Identification of anti-cyanobacterial leads targeting carbonic anhydrase from phytochemical database using in silico approach
Autorzy:: Padhiary, Archana
Mir, Showkat A.
Tete, Sheary S.
Baitharu, Iswar
Nayak, Binata
Tematy:: phytochemical database
lead optimizations
ADMET analysis
molecular docking simulations; Pokaż więcej
Wydawca:: Polska Akademia Nauk. Czasopisma i Monografie PAN
Powiązania:: https://bibliotekanauki.pl/articles/16704466.pdf Link otwiera się w nowym oknie
Opis:: In cyanobacteria, carbonic anhydrase (zinc metalloenzyme) is a major enzyme that converts CO2 to HCO3 maintaining the carbon concentration around the vicinity of RuBisCo, leading to cyanobacterial biomass generation. Anthropogenic activities, disposal of leached micro nutrients effluents from industries into the aquatic environment results in cyanobacterial blooms. The harmful cyanobacteria release cyanotoxins in open-water system which on ingression through oral route causes major health issues like hepatotoxicity and immunotoxicity. A database was prepared consisting of approximately 3k phytochemicals curated from previous literatures, earlier identified by GC-MS analysis. The phytochemicals were subjected to online servers to identify the novel lead molecules which followed ADMET and drug-like candidates. The identified leads were optimized by density functional theory method using B3YLP/G* level of theory. Carbonic anhydrase chosen as target to observe the binding interaction through molecular docking simulations. From the molecules included in the database the highest binding energy exhibited by alpha-tocopherol succinate and mycophenolic acid were found to be -9.23 kcal/mol and -14.41 kcal/mol and displayed interactions with GLY A102, GLN B30, ASP A41, LYS A105 including Zn2+ and their adjacent amino acids CYS 101, HIS 98, CYS 39 in both chain A and chain A-B of carbonic anhydrase. The identified molecular orbitals decipher computed global electrophilicity values (Energy gap, electrophilicity and Softness) of alpha tocopherol succinate and mycophenolic acid were found to be (5.262, 1.948, 0.380) eV and (4.710, 2.805, 0.424) eV demonstrates both molecules are effective and stable. The identified leads may serve as a better anti-carbonic anhydrase agent because they accommodate in the binding site and hampers the catalytic activity of Carbonic anhydrase thus inhibiting the generation of cyanobacterial biomass. This identified lead molecules may serve as a substructure to design novel phytochemicals against carbonic anhydrase present in cyanobacteria. Further in vitro study is necessary to evaluate the efficacy of these molecules.
Dostawca treści:: Biblioteka Nauki

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