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Tytuł:
Dyslipidemia management in patients with coronary artery disease. Data from the POLASPIRE survey
Autorzy:
Setny, Małgorzata
Kozieł, Paweł
Kosior, Dariusz A.
Paniczko, Marlena
Kotseva, Kornelia
Banach, Maciej
Kamiński, Karol
Haberka, Maciej
De Backer, Guy
De Bacquer, Dirk
Gąsior, Zbigniew
Jankowski, Piotr
Pająk, Andrzej
Wood, David
Opis:
Lipid-lowering in patients with coronary artery disease (CAD) is related to a lower risk of cardiovascular events. We evaluated factors related to the management of hypercholesterolemia in patients with established CAD. Patients were interviewed 6–18 months after hospitalization for an acute coronary syndrome (ACS) or a myocardial revascularization procedure. Statins were prescribed at discharge to 94.4% of patients, while 68.1% of the patients hospitalized for an ACS were prescribed a high-dose statin. Hospitalization in a teaching hospital, percutaneous coronary intervention, cholesterol measurement during hospitalization and the male sex were related to prescription of statins at discharge. The intensity of lipid-lowering therapy in the post-discharge period increased in 17.3%, decreased in 11.7%, and did not change in 71.0% of the patients. The prescription of a lipid-lowering drug (LLD) at discharge (odds ratio 5.88 [95% confidence intervals 3.05–11.34]) and a consultation with a cardiologist (2.48 [1.51–4.08]) were related to the use of LLDs, while age (1.32 [1.10–1.59] per 10 years), loneliness (0.42 [0.19–0.94]), professional activity (1.56 [1.13–2.16]), and diabetes (1.66 [1.27–2.16]) were related to achieving an LDL cholesterol goal 6–18 months after discharge. In conclusion, health-system-related factors are associated with the LLD utilization, whereas mainly patient-related factors are related to the control of hypercholesterolemia following hospitalization for CAD.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
Tytuł:
Częstość palenia tytoniu wśród osób z chorobą niedokrwienną serca w latach 1997–2007. Wyniki Krakowskiego Programu Wtórnej Prewencji Choroby Niedokrwiennej Serca oraz polskich części badań EUROASPIRE II i EUROASPIRE III
Autorzy:
Jankowski, Piotr
Kawecka-Jaszcz, Kalina
Surowiec, Sławomir
Loster, Magdalena
Wolfshaut, Renata
Pająk, Andrzej
Tematy:
coronary artery disease, risk factors, secondary prevention, smoking
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Wydawca:
Uniwersytet Jagielloński. Wydawnictwo Uniwersytetu Jagiellońskiego
Powiązania:
https://bibliotekanauki.pl/articles/635169.pdf  Link otwiera się w nowym oknie
Opis:
Smoking rates in coronary patients over the decade 1997–2007. Results of Cracovian Program for Secondary Prevention of Ischaemic Heart Disease and Polish parts of EUROASPIRE II and EUROASPIRE III surveysBackground: Smoking is one of the most important risk factors. Persisting smoking after an coronary event is related to significantly higher risk of the future cardiovascular complications. Studies performed in late nineties showed that a considerable percentage of patients continue with smoking after an coronary event. The aim of the present paper was to compare smoking rates in coronary patients in the post-discharge period in Krakow in 1997/1998, 1999/2000 and 2006/2007.Methods: Consecutive patients hospitalized from July 1, 1996 to September 31, 1997 (first survey), from March 1, 1998 to March 30, 1999 (second survey), and from April 1, 2005 to July 31, 2006 (third survey) due to acute myocardial infarction, unstable angina or for myocardial revascularization procedures, below the age of < 71 years were identified and then followed up, interviewed and examined 6–18 months after discharge. Self-reported smoking and breath carbon monoxide was analysed.Results: The number of patients who participated in the follow-up examinations were: 418 (78.0%) in the first survey, 427 (82.9%) in the second and 427 (79.1%) in the third survey. There was no significant change in smoking (self-reported) rates (16% vs 16% vs 19%; p = NS). When breath carbon monoxide was also analysed once again the difference did not reach significance (18% in 1999–2000 and 23% in 2006–2007; p = NS). Nicotine replacement therapy, bupropion or varenicline were also not used (0% vs 0.2% vs 0.5%; p = NS).Conclusion: The smoking rate in coronary patients over the decade from 1997/1998 to 2006/2007 did not changed significantly. The pharmacotherapy for smoking is almost not used in coronary patients.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Adherence to nutrition guidelines in patients with cardiovascular diseases as a secondary prevention
Autorzy:
Wozniak, A.
Krotki, M.
Anyzewska, A.
Gornicka, M.
Wawrzyniak, A.
Tematy:
human nutrition
human disease
patient
cardiovascular disease
secondary prevention
disease prevention
Pokaż więcej
Wydawca:
Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
Powiązania:
https://bibliotekanauki.pl/articles/877122.pdf  Link otwiera się w nowym oknie
Opis:
Background. The appropriate nutrition is an important component of the secondary prevention of cardiovascular diseases (CVD). Objectives. The aim of the study was to investigate if the patients with cardiovascular disease were informed of the role of appropriate nutrition in prevention or received nutrition guidelines and to assess the dietary intake compared to recommendations for patients with cardiovascular disease who received or not nutrition guidelines. Material and Methods. The study was conducted among patients with cardiovascular disease (n = 127) of cardiological hospital clinic, aged 62 ± 11. The questionnaire was used to obtain personal and anthropometric details, information if patients had received nutrition guidelines. The method of 3-day food records was used for dietary assessment. Results. 20% of subjects had not received nutrition guidelines and almost 40% of subjects did not recognize the nutrition effect on cardiovascular disease development. Compared to the diets of the subjects who had not received nutrition guidelines, the diets of those who had received them were of significantly lower intake of: energy from saturated fatty acids (15%, p = 0.006), cholesterol (21%, p = 0.012) and higher intake (14-26%) of potassium (p = 0,003), sodium (p = 0.013), phosphorus (p = 0.044), magnesium (p = 0.003), iron (p = 0.005), copper (p = 0.001), zinc (p = 0.046). Among the patients who had received nutrition guidelines, percentage of the subjects whose intake of nutrients was consistent with recommendations was higher. Conclusions. Not all subjects had received nutrition guidelines. Diets of those who had received them were more balanced, but in neither group nutrition guidelines were complied with.
Wprowadzenie. Prawidłowe żywienie jest ważnym elementem w ochronie wtórnej u pacjentów z chorobami układu sercowo-naczyniowego (CVD). Cel. Celem badania była ocena czy pacjenci ze zdiagnozowanymi chorobami układu sercowo-naczyniowego zostali poinformowani o roli odżywiania podczas leczenia oraz czy otrzymali zalecenia żywieniowe w ramach profilaktyki wtórnej, jak też ocena porównawcza sposobu żywienia osób, które otrzymały lub nie zalecenia żywieniowe. Materiał i metody. Badanie przeprowadzono wśród 127 pacjentów kliniki kardiologicznej jednego z warszawskich szpitali, pacjenci byli w wieku 62 ± 11 lat. Informacje nt. danych socjo-demograficznych i antropometrycznych oraz otrzymania zaleceń żywieniowych zostały zebrane za pomocą autorskiego kwestionariusza. Badane osoby wypełniły również kwestionariusz 3-dniowego bieżącego notowania spożycia żywności w celu oceny sposobu żywienia. Wyniki. Dwadzieścia procent osób nie otrzymało zaleceń żywieniowych, a prawie 40% osób nie dostrzegło wpływu żywienia na rozwój choroby. Odnotowano statystycznie istotne różnice w sposobie żywienia pomiędzy osobami, które uzyskały zalecenia żywieniowe a osobami, które takich zaleceń nie otrzymały, tj. niższy udział energii z nasyconych kwasów tłuszczowych (SFA) o 15%, niższe o 21% średnie spożycie cholesterolu oraz wyższe o 14-26% spożycie składników mineralnych, tj. potasu, sodu, fosforu, magnezu, żelaza, miedzi i cynku. Ponadto grupa osób, która otrzymała zalecenia żywieniowe charakteryzowała się lepszą realizacją norm na składniki żywieniowe i większą prawidłowością sposobu żywienia. Wnioski. Pomimo kluczowej roli, jaką odgrywa żywienie w profilaktyce i leczeniu chorób układu sercowo-naczyniowego, nie wszystkie badane osoby otrzymały wskazówki jak powinny się odżywiać. Osoby, które otrzymały zalecenia żywieniowe odżywiały się lepiej od tych, którym takich zaleceń nie przekazano, jednak ich sposób żywienia również odbiegał od norm i zaleceń.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Knowledge and prevalence of risk factors for coronary artery disease in patients after percutaneous coronary intervention and coronary artery bypass grafting
Autorzy:
Matysek, Mikołaj
Wójcicki, Krzysztof
Dudek, Dariusz
Dziewierz, Artur
Tokarek, Tomasz
Bartuś, Stanisław
Rakowski, Tomasz
Opis:
Background: Percutaneous coronary intervention (PCI) is associated with a short hospital stay and fast recovery. However, it might be related to insufficient implementation of lifestyle changes after the procedure. Conversely, coronary artery bypass grafting (CABG) is a highly invasive technique that requires a prolonged hospital stay and long rehabilitation with more opportunities for education. This study aimed to evaluate the impact of CABG on adherence to lifestyle modifications and knowledge about coronary artery disease (CAD) in comparison with PCI. We also evaluated the level of education and tried to define groups of patients that might require targeted education. Methods: Data was collected using a self-designed 56-item questionnaire. Questions assessed the knowledge of CAD risk factors and the level of their control. Results: The study group consisted of 155 consecutive patients admitted to the Cardiology Department. Patients with a history of PCI (68%) (at least 8 weeks before) were included in the prior-PCI group, and patients with previous surgical revascularization (also at least 8 weeks before) were assigned to the prior-CABG group (32%). The knowledge score was higher in the prior-CABG group. The median (IQR) results in the prior-PCI vs. prior-CABG group were, respectively: 20 (12–24) vs. 22 (19–25) [points, per 31 max.]; p = 0.01. Similar results were obtained in the level of risk control (prior-PCI vs. prior-CABG, respectively: 6 (4–7) vs. 7 (6–8) [points, per 15 max.]; p = 0.002). Conclusions: The method of treatment of CAD might impact the implementation of lifestyle modifications after the procedure. More effort is required to improve secondary prevention, especially in PCI patients.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
Tytuł:
Lipid-lowering therapy after acute coronary syndrome in outpatient practice - how to achieve goal
Autorzy:
Bobrowska, Beata
Rajtar-Salwa, Renata
Batko, Jakub
Bartuś, Stanisław
Petkow-Dimitrow, Paweł
Krawczyk-Ożóg, Agata
Opis:
Background: Secondary prevention of cardiovascular disease involves the use of optimal pharmacological treatment and modification of risk factors through lifestyle changes. Recent evidence demonstrates that the major initiating event in atherogenesis is the storage of low-density lipoproteins. Objectives: We aimed to compare the efficacy in achieving the therapeutic lipid target in relation to the frequency of follow-up at selected time points and to determine the safety and tolerability of cholesterol-lowering drugs (statins, ezetimibe). Methods: This was a prospective analysis of 72 consecutive patients hospitalized for acute coronary syndrome: ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction (NSTEMI). Patients were consecutively divided into two groups: first, with follow-up and laboratory tests at 1, 3, 6 and 12 months after hospital discharge, including 32 patients; second, including 40 patients with follow-up and laboratory tests 12 months after hospital discharge. Results: A significant reduction in LDL-C level was observed at 12 months in both groups. LDL-C level was significantly lower in group 1 than in group 2 after 12 months (p = 0.02). Total cholesterol level was significantly lower in group 1 than in group 2 after 12 months. After 12 months of therapy, 21 (65.6%) patients in group 1 and 17 (42.5%) in group 2 had LDL-C < 1.4 mmol/L. In group 1, we observed a significant decrease in LDL-C, triglyceride, and total cholesterol levels at 1, 3, 6 and 12 months (p < 0.05). Conclusions: The group of patients with more frequent follow-up visits showed a greater reduction in LDL-C level than the group with only one visit after a 12-month hospital discharge.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
Tytuł:
Subsequent event risk in individuals with established coronary heart disease : design and rationale of the GENIUS-CHD consortium
Autorzy:
Sun, Yan
Delgado, Graciela
Carpeggiani, Clara
Pilbrow, Anna
Lee, Vei-Vei
Kofink, Daniel
Wallentin, Lars
Fox, Keith
Lang, Chim
Nikus, Kjell
Patel, Riyaz
Mahmoodi, B.
Simon, Tabassome
Gong, Yan
Pare, Guillaume
Al Ali, Lawien
Deloukas, Panos
Mons, Ute
James, Stefan
Laurikka, Jari
Szczeklik, Wojciech
ten Berg, Jurrien
Holmes, Michael
Kaminski, Karol
van der Graaf, Yolanda
Quyyumi, Arshed
Muehlschlegel, Jochen
Stender, Steen
Dube, Marie-Pierre
Stewart, Alexandre
Brenner, Hermann
Hartiala, Jaana
Hovingh, G.
Brugts, Jasper
Jukema, J.
Dudbridge, Frank
Richards, A.
Baranova, Ekaterina
Van de Werf, Frans
Scholz, Markus
Fitzpatrick, Natalie
Cresci, Sharon
Gijsberts, Crystel
Niemcunowicz-Janica, Anna
McPherson, Ruth
Lotufo, Paulo
Tang, W.H.
Drexel, Heinz
Alver, Maris
Danchin, Nicolas
Burkhardt, Ralph
Wilde, Arthur
Anderson, Jeffrey
McCubrey, Raymond
Marziliano, Nicola
Pereira, Alexandre
Pepine, Carl
Pilote, Louise
Saely, Christoph
Carlquist, John
Grobbee, Diederick
Kleber, Marcus
Direk, Kenan
Lindholm, Daniel
Martinelli, Nicola
Sandesara, Pratik
Ardissino, Diego
Girelli, Domenico
Leiherer, Andreas
Johnson, Julie
Bogaty, Peter
Lagerqvist, Bo
Lehtimaki, Terho
Arsenault, Benoit
Levin, Daniel
Bots, Michiel
Kaczor, Marcin
Doughty, Robert
Virani, Salim
Sinisalo, Juha
Siegbahn, Agneta
Boersma, Eric
Wauters, Els
Algra, Ale
Duarte, Nubia
Lokki, Marja-Liisa
Engert, James
Smith, J.
Schmidt, Amand
Trompet, Stella
Marz, Winfried
Kettner, Jiri
van Setten, Jessica
Hagstrom, Emil
Sanak, Marek
Boeckx, Bram
Lenzini, Petra
Klungel, Olaf
Cooper-DeHoff, Rhonda
Body, Simon
Kahonen, Mika
Hingorani, Aroon
Breitling, Lutz
van der Laan, Sander
Tragante, Vinicius
Pitha, Jan
Samman-Tahhan, Ayman
Szpakowicz, Anna
Nelson, Christopher
Tanck, Michael
Deanfield, John
Spertus, John
Held, Claes
Tfelt-Hansen, Jacob
Condorelli, Gianluigi
Horne, Benjamin
Ballantyne, Christie
Sattar, Naveed
Melander, Olle
Metspalu, Andres
Tardif, Jean-Claude
Visseren, Frank
Ford, Ian
Teren, Andrej
Allayee, Hooman
Waltenberger, Johannes
Foco, Luisa
Hoefer, Imo
Maitland-van der Zee, Anke
Jabbari, Reza
Muhlestein, Joseph
Akerblom, Axel
Kuukasjarvi, Pekka
Palmer, Colin
Stott, David
Engstrom, Thomas
Thanassoulis, George
Eriksson, Niclas
de Faire, Ulf
Hubacek, Jaroslav
Lambrechts, Diether
Hazen, Stanley
Boerwinkle, Eric
Glinge, Charlotte
Heydarpour, Mahyar
Pasterkamp, Gerard
Dufresne, Line
Bezzina, Connie
Newton-Cheh, Christopher
Behlouli, Hassan
Anselmi, Chiara
Casu, Gavino
Lyytikainen, Leo-Pekka
Leander, Karin
Vlachopoulou, Efthymia
Gigante, Bruna
Andreassi, Maria
Bergmeijer, Thomas
Cameron, Vicky
Asselbergs, Folkert
Kiliszek, Marek
Carruthers, Kathryn
Thiery, Joachim
Brophy, James
Braund, Peter
Fox, Kim
Almgren, Peter
Hemingway, Harry
Briguori, Carlo
Timmis, Adam
van der Harst, Pim
Opolski, Grzegorz
Samani, Nilesh
Vilmundarson, Ragnar
Howe, Laurence
Ploski, Rafal
Torp-Pedersen, Christian
Olivieri, Oliviero
Kotti, Salma
Opis:
BACKGROUND: The Genetics of Subsequent Coronary Heart Disease (GENIUS-CHD) consortium was established to facilitate discovery and validation of genetic variants and biomarkers for risk of subsequent CHD events, in individuals with established CHD. METHODS: The consortium currently includes 57 studies from 18 countries, recruiting 185 614 participants with either acute coronary syndrome, stable CHD, or a mixture of both at baseline. All studies collected biological samples and followed-up study participants prospectively for subsequent events. RESULTS: Enrollment into the individual studies took place between 1985 to present day with a duration of follow-up ranging from 9 months to 15 years. Within each study, participants with CHD are predominantly of self-reported European descent (38%-100%), mostly male (44%–91%) with mean ages at recruitment ranging from 40 to 75 years. Initial feasibility analyses, using a federated analysis approach, yielded expected associations between age (hazard ratio, 1.15; 95% CI, 1.14-1.16) per 5-year increase, male sex (hazard ratio, 1.17; 95% CI, 1.13-1.21) and smoking (hazard ratio, 1.43; 95% CI, 1.35-1.51) with risk of subsequent CHD death or myocardial infarction and differing associations with other individual and composite cardiovascular endpoints. CONCLUSIONS: GENIUS-CHD is a global collaboration seeking to elucidate genetic and nongenetic determinants of subsequent event risk in individuals with established CHD, to improve residual risk prediction and identify novel drug targets for secondary prevention. Initial analyses demonstrate the feasibility and reliability of a federated analysis approach. The consortium now plans to initiate and test novel hypotheses as well as supporting replication and validation analyses for other investigators.
Dostawca treści:
Repozytorium Uniwersytetu Jagiellońskiego
Artykuł
Wyświetlanie 1-10 z 56

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