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Wyszukujesz frazę "sensitivity analysis" wg kryterium: Temat


Tytuł:
Sensitivity analysis of deterministic signaling pathways models
Autorzy:
Puszyński, K.
Lachor, P.
Kardyńska, M.
Śmieja, J.
Tematy:
signaling pathways
sensitivity analysis
Pokaż więcej
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Powiązania:
https://bibliotekanauki.pl/articles/201589.pdf  Link otwiera się w nowym oknie
Opis:
The paper is focused on application of sensitivity methods to analysis of signaling pathway models. Two basic methods are compared: local, based on standard sensitivity functions, and global, based on Sobol indices. Firstly, a general outline of modeling of signaling pathways by means of ordinary differential equations is briefly described. Afterwards, the methods of sensitivity analysis, known from literature, are introduced and illustrated with a simple example of a dynamical system of the second order. Subsequently, the analysis of the p53/Mdm2 regulatory module, which is a key element of any pathway involving p53 protein, is presented. The results of this analysis suggest that no single method should be chosen for investigation of any signaling pathway model but several of them should be applied to answer important questions about sources of heterogeneity in cells behavior, robustness of signaling pathways and possible molecular drug targets.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Economic analysis of implementing VMI model using game theory
Autorzy:
Stehel, Vojtěch
Vochozka, Marek
Kliestik, Tomas
Bakes, Vladimir
Tematy:
VMI
game theory
sensitivity analysis
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Wydawca:
Instytut Badań Gospodarczych
Powiązania:
https://bibliotekanauki.pl/articles/19090921.pdf  Link otwiera się w nowym oknie
Opis:
Research background: The article deals with implementing VMI between the supplier and customer. To assess whether the system will be implemented, the evolution game theory is used. The contribution is based on the limitations of the study of the evolutionary game theory approach to modelling VMI policies (Torres et al., 2014) and its later extension, The evolutionary game theory approach to modelling VMI policies (Torres & García-Díaz, 2018). It aims is to complement the studies and provide a comprehensive picture of the issue. Purpose of the article: The main objective of the contribution is to respond to the question whether the VMI system will be introduced between the supplier and customer. Methods: In the first phase, the matrix is analysed from the point of view of the game meaning and its limit parameters. The limit parameters are set taking into account the economic reality. The only examined states of the matrix are those where the result is not obvious. For the purposes of the contribution, we work with a 5-year period. A new software capable of calculating evolutionary focus and their stability is created. Sensitivity analysis is carried out for the individual parameters that affect the system behaviour. Findings & Value added: Value added is a complex description of the system and complementation of previous studies in this field. VMI is confirmed. The results obtained can be used for practical management, so that the managers are able to identify what the actual costs are and what the probability of introducing the system is. At the same time, they can identify the parameters that can be influenced by them and observe their impact on the shift of the system introduction probability.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
High order sensitivity analysis of a mistuned blisk including intentional mistuning
Autorzy:
Pohle, L.
Tatzko, S.
Panning-von Scheidt, L.
Wallaschek, J.
Tematy:
turbine blades
mistuning
sensitivity analysis
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Wydawca:
Polskie Towarzystwo Mechaniki Teoretycznej i Stosowanej
Powiązania:
https://bibliotekanauki.pl/articles/281842.pdf  Link otwiera się w nowym oknie
Opis:
Small deviations between turbine blades exist due to manufacturing tolerances or material inhomogeneities. This effect is called mistuning and usually causes increased vibration amplitudes and also a lower service life expectancy of bladed disks or so called blisks (bladed integrated disk). The major resulting problem is to estimate the maximum amplitude with respect to these deviations. Due to the probability distribution of these deviations, statistical methods are used to predict the maximum amplitude. State of the art is the Monte-Carlo simulation which is based on a high number of randomly re-arranged input parameters. The aim of this paper is to introduce a useful method to calculate the probability distribution of the maximum amplitude of a mistuned blisk with respect to the random input parameters. First, the applied reduction method is presented to initiate the sensitivity analysis. This reduction method enables the calculation of the frequency response function (FRF) of a Finite Element Model (FEM) in a reasonable calculation time. Based on the Taylor series approximation, the sensitivity of the vibration amplitude depending on normally distributed input parameters is calculated and therewith, it is possible to estimate the maximum amplitude. Calculating only a single frequency response function shows a good agreement with the results of over 1000 Monte-Carlo simulations.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sensivity and design of fiber layout in composites
Autorzy:
Dems, K.
Tematy:
sensitivity analysis
composites
fiber layout
optimization
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Wydawca:
Polskie Towarzystwo Mechaniki Teoretycznej i Stosowanej
Powiązania:
https://bibliotekanauki.pl/articles/279497.pdf  Link otwiera się w nowym oknie
Opis:
For a linear structure reiforced with elastic fibers, the first variation of an arbitrary behavioral functional corresponding to variation of shape or orientation of fibers is derived by using the direct approach to sensivity analysis. The relevant optimality conditions for optimal design and identification problems are then derived. Both the static and dynamic loading cases are considered. Some simple examples illustrate the applicability of the presented approach.
Wrażliwość i projektowanie ułożenia włókien w kompozycie. W pracy rozpatrzono pierwszą wariację dowolnego funkcjonału związaną z wariacją kształtu lub orientacji wzmacniających włókien w płaskiej liniowo-sprężystej tarczy. Wrażliwości rozpatrywanego funkcjonału wyznaczono wykorzystując metodę bezpośrednią analizy wrażliwości. Następnie sformułowano typowy problem optymalnego projektowania oraz problem identyfikacyjny i wyznaczono odpowiednie warunki optymalności. Rozpatrzono zarówno przypadek obciążeń statycznych, jak i dynamicznych.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sensitivity Analysis and Optimization for Selected Supply
Autorzy:
Marjasz, Rafał
Kasperska, Elżbieta
Mateja-Losa, Elwira
Wydawca:
Wyższa Szkoła Biznesu - National Louis Univeristy
Cytata wydawnicza:
Kasperska, E., Mateja-Losa, E., Marjasz, R., Sensitivity Analysis and Optimization for Selected Supply Chain Management Issues in the Company – Using System Dynamics and Vensim. Journal of Entrepreneurship, Management and Innovation (JEMI), 2013, vol. 9, nr 2 : System Theories and Practice. Ed. by M. Baran, K. Śliwa, s. 29-44
Opis:
The aim of our paper is to present the new results of research work on optmizaton and simulaton for some logistc problems in the company. The System Dynamics (SD) method and the Vensim simulaton language are applied in order to solve specifc managerial problems described by Forrester in the model of supply chain. The historical model of Customer-Producer-Employment System by Forrester (Forrester, 1961) has not been examined with the sensitvity analysis, from the “automatc” testng perspectve. Optmizaton experiments have not been conducted, either. It is surprising, since the model is old and widely known. The opportunites offered by the Vensim language allow us to perform such analysis. The visualizaton called “confdence bounds“ is used, to show the behaviour of chosen variables over a period of tme. The Monte-Carlo method is applied for sampling a set of numbers from within bounded domains (distributon for each searching parameters is specifed). The authors of this paper conducted numerous experiments in this scope. This paper presents their results and offers some conclusions formulated at the end.
Dostawca treści:
Repozytorium Centrum Otwartej Nauki
Artykuł
Tytuł:
Exploring the role of socio-economic and built environment driving factors in shaping the commuting modal share: a path-analysis-based approach
Autorzy:
Boukarta, Soufiane
Berezowska-Azzag, Ewa
Tematy:
commuting
questionnaire
sensitivity analysis
path analysis
Djelfa (Algeria)
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Wydawca:
Uniwersytet im. Adama Mickiewicza w Poznaniu
Powiązania:
https://bibliotekanauki.pl/articles/1050982.pdf  Link otwiera się w nowym oknie
Opis:
This paper explores the role of the built environment and socio-economic drivers in shaping the modal share of commuting. For this, we have identified through our literature review 67 potential variables categorised into two groups; the built environment and the households’ socio-economic characteristics. We have considered the city of Djelfa as a case study and used the questionnaire as a data collection tool. The questionnaire processing of the 700 questionnaires provided to the households allowed us to select 184 questionnaires for our analysis. The sensitivity analysis protocol is designed for two stages; (i) an exploratory stage, conducted by principal component analysis and bivariate correlation analysis; (ii) and a confirmatory stage conducted by a path analysis. The first step allowed us to hypothesise several causal pathways that could explain, directly or indirectly, the modal share of commuting. The results of the path analysis show that the modal shares of walking, private car and public transit are controlled by 13, 16 and 12 explanatory variables, respectively. Overall, the socio-economic characteristics of households discourage walking and transit use, and encourage private car commuting. On the other hand, the variables identified in this paper related to the built environment discourage walking, but encourage the use of public transit rather than private cars for commuting.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A remark on sensitivity in linear programming and Gale-Samuelson nonsubstitution theorem
Autorzy:
De Giuli, M. E.
Giorgi, G.
Tematy:
linear programming
sensitivity analysis
nonsubstitution theorem
Pokaż więcej
Wydawca:
Polska Akademia Nauk. Instytut Badań Systemowych PAN
Powiązania:
https://bibliotekanauki.pl/articles/969906.pdf  Link otwiera się w nowym oknie
Opis:
The main purpose of this paper is to show that David Gale's result (1960, Lemma 9.3 on sensitivity in linear programming) is not generally valid. In this lemma, additional assumptions, that are instead required, are not made. We give some correct versions of the above mentioned lemma, and with these an elementary proof of the Gale-Samuelson nonsubstitution theorem.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sensitivity Analysis and Optimization for Selected Supply Chain Management Issues in the Company – Using System Dynamics and Vensim
Autorzy:
Kasperska, Elżbieta
Mateja-Losa, Elwira
Marjasz, Rafał
Tematy:
System Dynamics
sensitivity analysis
optimization
Vensim
Pokaż więcej
Wydawca:
Fundacja Upowszechniająca Wiedzę i Naukę Cognitione
Powiązania:
https://bibliotekanauki.pl/articles/475034.pdf  Link otwiera się w nowym oknie
Opis:
The aim of our paper is to present the new results of research work on optimization and simulation for some logistic problems in the company. The System Dynamics (SD) method and the Vensim simulation language are applied in order to solve specific managerial problems described by Forrester in the model of supply chain. The historical model of Customer-Producer-Employment System by Forrester (Forrester, 1961) has not been examined with the sensitivity analysis, from the “automatic” testing perspective. Optimization experiments have not been conducted, either. It is surprising, since the model is old and widely known. The opportunities offered by the Vensim language allow us to perform such analysis. The visualization called “confidence bounds“ is used, to show the behaviour of chosen variables over a period of time. The Monte-Carlo method is applied for sampling a set of numbers from within bounded domains (distribution for each searching parameters is specified). The authors of this paper conducted numerous experiments in this scope. This paper presents their results and offers some conclusions formulated at the end.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Constructing improvement plan for inputs through dialogue with DM about DEA-Efficiency for DMUs
Autorzy:
Uemura, Y.
Tematy:
evaluation efficiency
partial improvement plan
sensitivity analysis
Pokaż więcej
Wydawca:
Polska Akademia Nauk. Instytut Badań Systemowych PAN
Powiązania:
https://bibliotekanauki.pl/articles/206812.pdf  Link otwiera się w nowym oknie
Opis:
Evaluation of efficiency of the DMUs (Decision Making Units) in a company is a very important problem. Thus, the studies of evaluation of efficiency are being actively carried out on the basis of the production functions, for example Cobb-Douglas production function and fuzzy loglinear production function (fuzzy Cobb-Douglas model). Recently, DEA (Data Envelopment Analysis) was applied to evaluation of efficiency, in the sense of benchmarking evaluation. After having evaluated DMUs by DEA, we obtain the improvement plan for every input in the inefficient DMUs. Though we many not be able to decrease inputs at one time according to the DEA plan, it is natural to construct some phased improvement plans for decreasing the inputs. First, we propose to support the construction of some phased improvement plans by the sensitivity analysis for the evaluated efficiency by applicatiion of definite limits to the decrease of inputs. Second, we evaluate this method by applying it to the case of bank data.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sensitivity analysis of biological tissue freezing process with respect to the radius of spherical cryoprobe
Analiza wrażliwości procesu zamrażania tkanki biologicznej ze względu na promień kriosondy sferycznej
Autorzy:
Majchrzak, E.
Kałuża, G.
Tematy:
freezing process
boundary element method
sensitivity analysis
Pokaż więcej
Wydawca:
Polskie Towarzystwo Mechaniki Teoretycznej i Stosowanej
Powiązania:
https://bibliotekanauki.pl/articles/280301.pdf  Link otwiera się w nowym oknie
Opis:
Application of the shape sensitivity analysis to the case of problems of the biological tissue freezing process is discussed. The freezing process described by a strongly non-linear bioheat transfer equation in which an additional term controlling the evolution of latent heat appears. Using the approach called 'the one domain method', one finally obtains a partial differential equation containing the substitute thermal capacity of tissue. The boundary and initial conditions determine the thermal interaction between the tissue and cryoprobe tip. In the paper, we consider a spherical internal cryoprobe. In order to estimate the influence of cryoprobe geometry on the course of the process, the shape sensitivity analysis is applied. In particular, a direct approach is used (explicit differentiation method). The results of numerical modeling (the boundary element method is applied) allow one to formulate essential practical conclusions concerning the course of cryosurgery treatments.
Praca dotyczy zastosowania analizy wrażliwości kształtu w zagadnieniach modelowaniaprocesuzamrażania tkanki biologicznej. Proces ten jest opisany silnie nieliniowym równaniem przepływu biociepła, w którym pojawia się dodatkowy składnik związany z wydzielaniem się utajonego ciepła zamrażania. Formalne przekształcenia wyjściowego równania opisującego proces prowadzi do równania różniczkowego, w którym występuje zastępcza pojemność cieplna tkanki (tzw. metoda jednego obszaru). Odpowiednio przyjęte warunki brzegowe determinują oddziaływania termiczne między tkanką a końcówką kriosondy. W pracy rozważa się sferyczną kriosondę wewnętrzną. VV celu oszacowania wpływu geometrii kriosondy na przebieg procesu zamrażania wykorzystano podejście bezpośrednie analizy wrażliwości kształtu. Wyniki obliczeii numerycznych otrzymane za pomocą metody elementów brzegowych pozwoliły na sformułowanie wniosków przydatnych w praktyce kriochirurgicznej.
Dostawca treści:
Biblioteka Nauki
Artykuł

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