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Wyszukujesz frazę "susceptibility" wg kryterium: Temat


Tytuł:
Microfluidics for antibiotic susceptibility testing
Autorzy:
Garstecki, Piotr
Postek, Witold
Pacocha, Natalia
Wydawca:
Royal Society of Chemistry
Cytata wydawnicza:
Lab Chip, 2022, 10.1039/d2lc00394e
Opis:
The rise of antibiotic resistance is a threat to global health. Rapid and comprehensive analysis of infectious strains is critical to reducing the global use of antibiotics, as informed antibiotic use could slow down the emergence of resistant strains worldwide. Multiple platforms for antibiotic susceptibility testing (AST) have been developed with the use of microfluidic solutions. Here we describe microfluidic systems that have been proposed to aid AST. We identify the key contributions in overcoming outstanding challenges associated with the required degree of multiplexing, reduction of detection time, scalability, ease of use, and capacity for commercialization. We introduce the reader to microfluidics in general, and we analyze the challenges and opportunities related to the field of microfluidic AST.
Narodowe Centrum Nauki (NCN), Polish National Agency for Academic Exchange (NAWA), Foundation for Polish Science (FNP)
Dostawca treści:
Repozytorium Centrum Otwartej Nauki
Artykuł
Tytuł:
Immune response gene polymorphisms in tuberculosis
Autorzy:
Fol, Marek
Druszczynska, Magdalena
Wlodarczyk, Marcin
Ograczyk, Elzbieta
Rudnicka, Wieslawa
Tematy:
tuberculosis
susceptibility/resistance genes
Pokaż więcej
Wydawca:
Polskie Towarzystwo Biochemiczne
Powiązania:
https://bibliotekanauki.pl/articles/1038871.pdf  Link otwiera się w nowym oknie
Opis:
Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis (M.tb), remains a leading public health problem in most parts of the world. Despite the discovery of the bacilli over 100 years ago, there are still many unanswered questions about the host resistance to TB. Although one third of the world's population is infected with virulent M.tb, no more than 5-10% develop active disease within their lifetime. A lot of studies suggest that host genetic factors determine the outcome of M.tb-host interactions, however, specific genes and polymorphisms that govern the development of TB are not completely understood. Strong evidence exists for genes encoding pattern recognition receptors (TLR, CD14), C-type lectins, cytokines/chemokines and their receptors (IFN-γ, TNF-α, IL-12, IL-10, MCP-1, MMP-1), major histocompatibility complex (MHC) molecules, vitamin D receptor (VDR), and proton-coupled divalent metal ion transporters (SLC11A1). Polymorphisms in these genes have a diverse influence on the susceptibility to or protection against TB among particular families, ethnicities and races. In this paper, we review recent discoveries in genetic studies and correlate these findings with their influence on TB susceptibility.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Antimicrobial resistance in Rhodococcus equi
Autorzy:
Cisek, Agata
Rzewuska, Magdalena
Witkowski, Lucjan
Binek, Marian
Tematy:
antimicrobial susceptibility
Rhodococcus equi
Pokaż więcej
Wydawca:
Polskie Towarzystwo Biochemiczne
Powiązania:
https://bibliotekanauki.pl/articles/1039187.pdf  Link otwiera się w nowym oknie
Opis:
Rhodococcus equi is an important etiologic agent of respiratory- and non-respiratory tract infections, diseases of animals and humans. Therapy includes the use of various group of chemotherapeutic agents, however resistance acquirement is quite common. To date there is no preferred treatment protocol for infections caused by isolates resistant to macrolides and rifampicin. The resistance acquirement is a result of many molecular mechanisms, some of which include alterations in the cell envelope composition and structure, activity of the efflux pumps, enzymatic destruction or inactivation of antibiotics, and changes in the target site. This paper contains an overview of antimicrobial susceptibility of R. equi, and explains the possible molecular mechanisms responsible for antimicrobial resistance in this particular microorganism.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Cluster Superconductivity in the Magnetoelectric $Pb(Fe_{1//2}Sb_{1//2})O_3$ Ceramics
Autorzy:
Laguta, V.
Marysko, M.
Stephanovich, V.
Raevsky, I.
Olekhnovich, N.
Pushkarev, A.
Radyush, Yu.
Raevskaya, S.
Kuzian, R.
Chlan, V.
Štěpánková, H.
Tematy:
Multiferroics
Superconductivity
magnetic susceptibility
Pokaż więcej
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Powiązania:
https://bibliotekanauki.pl/articles/1398326.pdf  Link otwiera się w nowym oknie
Opis:
We report the observation of cluster (local) superconductivity in the magnetoelectric $Pb(Fe_{1//2}Sb_{1//2})O_3$ ceramics prepared at a hydrostatic pressure of 6 GPa and temperatures 1200-1800 K to stabilize the perovskite phase. The superconductivity is manifested by an abrupt drop of the magnetic susceptibility at the critical temperature $T_{c}$ ≈7 K. Both the magnitude of this drop and $T_{c}$ decrease with magnetic field increase. Similarly, the low-field paramagnetic absorption measured by EPR spectrometer drops significantly below $T_{c}$ as well. The observed effects and their critical magnetic field dependence are interpreted as manifestation of the superconductivity and the Meissner effect in metallic Pb nanoclusters existing in the ceramics. Their volume fraction and average size were estimated as 0.1-0.2% and 140-150 nm, respectively. The superconductivity related effects disappear after oxidizing annealing of the ceramics.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Multi parametric GIS analysis to assess gully erosion susceptibility : a test in southern Sicily, Italy
Autorzy:
Agnesi, V.
Angileri, S.
Cappadonia, C.
Conoscenti, C.
Rotigliano, E.
Tematy:
gully erosion
GIS
susceptibility
Sicily
Pokaż więcej
Wydawca:
Stowarzyszenie Geomorfologów Polskich
Powiązania:
https://bibliotekanauki.pl/articles/294669.pdf  Link otwiera się w nowym oknie
Opis:
A GIS+analysis was carried out in a test basin of southern Sicily, the Magazzolo River basin, in order to assess susceptibility conditions to gully erosion phenomena. The linear density of ephemeral and permanent gullies computed within each class of nine environmental variables was used to generate a gully erosion susceptibility map for the area. A validation procedure carried out in order to test the reliability of the adopted method highlighted a clear correlation between the occurrence of gullies and the computed susceptibility levels.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Magnetic classification of meteorites and application to the Sołtmany fall
Autorzy:
Rochette, P.
Gattacceca, J.
Lewandowski, M.
Tematy:
magnetic susceptibility
meteorite classification
Sołtmany
Pokaż więcej
Wydawca:
Polskie Towarzystwo Meteorytowe
Powiązania:
https://bibliotekanauki.pl/articles/411478.pdf  Link otwiera się w nowym oknie
Opis:
We review the use of magnetic susceptibility measurements to classify meteorites, showing that magnetic susceptibility of meteorites vary over 3 orders of magnitude and shows often a narrow range for a given meteorite group, especially in chondrites. Weathering of metal may bias the magnetic classification. For ordinary chondrite falls, the method is quite robust, as shown by its application to the recent Sołtmany fall.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Pollution Determined by Using Magnetic Susceptibility Measurements: A Case Study from İzmir-Aliağa
Autorzy:
Kamaci, Z.
Uysal, G.
Tematy:
environmental geophysics
pollution
magnetic susceptibility
Pokaż więcej
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Powiązania:
https://bibliotekanauki.pl/articles/1031417.pdf  Link otwiera się w nowym oknie
Opis:
Wherever industrial development exists, environmental pollution increases day by day. The heavy metals play an important role in soil and environmental pollutions and directly affect the human being lives. In this study, we determine pollutions resulting from heavy metal particles emanating from the brake discs pads of the vehicles on high ways and nearby factories. The field work was carried out in İzmir-Aliağa industrial area. Magnetic susceptibility measurements were done at a long profile crossing the İzmir-Çanakkale highway that goes through the study area. Here, we have determined the effect of heavy metals causing pollution in the surroundings. The studies indicate that the average acceptable values of magnetic susceptibility in such areas is about 0-50×10¯⁵ SI. Here we show that the magnetic susceptibility measurement values obtained along our study profile are about 18 times the acceptable ranges.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Antimicrobal susceptibility pattern of methicillin resistant Staphylococcus aureus isolatetd from pediatric clinical samples at Webuye District Hospital
Autorzy:
Kibaba, P. W.
Louis, H.
Kering, K. K.
Matiru, V. N.
Tematy:
Antimicrobial
MRSA
Staphyoloccocus aureus
Susceptibility
Pokaż więcej
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Powiązania:
https://bibliotekanauki.pl/articles/1179606.pdf  Link otwiera się w nowym oknie
Opis:
Methicillin Resistant Staphylococcus aureus (MRSA) is an important nosocomial pathogen causing a significant mortality and morbidity. The main objective of the study was to establish antibiotic susceptibility pattern MRSA isolated from pediatrics clinical samples at Webuye District Hospital. A total of 96 clinical samples that include blood, abscess, ear swabs, and urine and wound/pus swabs were collected by simple random techniques. These samples were cultured onto Blood agar and MacConkey agar respectively and incubated at 37oC for 24 hours. In the result 83 (86.5%) clinical samples had pure colonies of S. aureus which were identified morphologically and biochemically by standard laboratory procedures using Bergey’s Manual of Clinical Microbiology. All confirmed positive isolates were screened for MRSA whereby 18 (21.7%) were MRSA and these were subjected to susceptibility testing to common antibiotics by modified Kirby-Bauer disc diffusion method. The susceptibility was interpreted according to National Clinical laboratory Standard guidelines. From the study the prevalence of MRSA was 18 (21.7%) with the highest obtained in the wound/pus swab. Almost all MRSA was resistant to penicillin (92.8%) and cephalexin (96.6%) and amoxicillin (91%). The most effective antibiotics against the of MRSA strain were vancomycin (98.97%), ciprofloxacin (88.4%) and gentamycin (83.06%). Vancomycin was the most effective drug showed the largest inhibition zone.
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The magnetic susceptibility of soils and alluvial sediments from Gdansk region (northern Poland)
Autorzy:
Nawrocki, J.
Lis, J.
Grabowski, J.
Pasieczna, A.
Tematy:
Gdańsk region
magnetic susceptibility
pollution
Pokaż więcej
Wydawca:
Państwowy Instytut Geologiczny – Państwowy Instytut Badawczy
Powiązania:
https://bibliotekanauki.pl/articles/2059451.pdf  Link otwiera się w nowym oknie
Opis:
Volume magnetic susceptibility of soils and alluvial sediments from the eastern Pomeranian region near Gdańsk was investigated. Full set of geochemical analyses had been previously performed for all the samples studied. The results are presented in the form of the susceptibility maps of the topsoil horizon, the subsoil at the depth between 40 and 60 cm and the alluvial sediments. Additionally the differential susceptibility map between topsoil horizon and the subsoil at the depth 40-60 cm has been also constructed. A close correlation is observed between positive anomalies of differential susceptibility and urban areas. This is interpreted as surface anthropogenic pollution. Magnetic susceptibility values higher than 1200 x 10-6 SI units, observed in topsoil horizon, might reflect high contents of such elements as Ba, Co, Mg, Mn and Ni.
Dostawca treści:
Biblioteka Nauki
Artykuł

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